Inherited thrombocytopenias predisposing to hematological malignancies

EHA Library, Hana Raslova, 137029

Panel Discussion

EHA Library, Faculty / Presenters, 137627

Predictors of bleeding in thrombocytopenic patients

EHA Library, PAOLO GRESELE, 137028

New treatment approaches in Hodgkin lymphoma in 2016

EHA Library, Igor Aurer, 136643

Risk adapted treatment of early stage HL

EHA Library, Marc Andre, 136642

Pathogenesis of HL

EHA Library, Ralf Küppers, 136641

Treatment of the elderly CLL patients

EHA Library, Barbara Eichhorst, 136640

Prognostic and predictive factors in the era of new targeted therapies

EHA Library, Davide Rossi, 136639

B-cell receptor structure and function in CLL

EHA Library, Francesco Forconi, 136638

Evidence based transfusion medicine for coagulopathy in patients with CLD

EHA Library, Pratima Choudary, 136637

Transfusion management of coagulation abnormalities in CLD: From bench to bedside

EHA Library, Armando Tripodi, 136636

Hemostasis and thrombosis in patients with liver disease

EHA Library, Ton Lisman, 136635

Primary CNS Lymphoma

EHA Library, Andres Jose Maria Ferreri, 136634

Histiocytic disorders of children and adults

EHA Library, Maarten Egeler, 136633

Systemic Mastocytosis for the Hematologist

EHA Library, Hanneke Kluin-Nelemans, 136632

Immunological predictors of successful treatment discontinuation

EHA Library, Satu Mustjoki, 136631

What have we learned from stopping TKI treatment in CML?

EHA Library, Susanne Saussele, 136630

Modeling CML blast crisis

EHA Library, Brian Huntly, 136629

Primary cutaneous B-cell lymphomas

EHA Library, Rein Willemze, 136628

Intravascular Large B-cell Lymphoma

EHA Library, Maurilio Ponzoni, 136627

NF-kappaB cooperating events in mature B cell derived malignancies

EHA Library, Dinis Calado, 136626

Smoldering MM

EHA Library, Maria Victoria Mateos, 136625

Pathophysiology and diagnosis of MM bone disease

EHA Library, Evangelos Terpos, 136624

Molecular architecture of MM

EHA Library, Brian Walker, 136623

USE OF VOXEL-BASED MORPHOMETRY TO DETECT CEREBRAL VOLUMES ABNORMALITIES IN LONG TERM SURVIVORS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA.

EHA Library, Rosanna Parasole, 132411

HYPER-CVAD COMPARED TO BFM-LIKE CHEMOTHERAPY FOR THE TREATMENT OF ADULT ACUTE LYMPHOBLASTIC LEUKEMIA. A RETROSPECTIVE SINGLE CENTER ANALYSIS

EHA Library, Jean El Cheikh, 132412

BFM REGIMEN OFFERS SIMILAR EVENT FREE SURVIVAL COMPARED TO HYPERCVAD BUT WITH LESS TOXICITY IN ADOLESCENTS AND YOUNG PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Arturo Vega, 132413

PATTERN OF CNS RELAPSE IN ACUTE LYMPHOBLASTIC LEUKEMIA BCR-ABL POSITIVE, THE IMPORTANCE OF CHARACTERIZATION OF ABL1 MUTATIONS IN CEREBROSPINAL FLUID.

EHA Library, Joaquin Martinez-Lopez, 132414

PROGNOSTIC IMPACT OF COPY NUMBER ALTERATIONS IN A SERIES OF PEDIATRIC PATIENTS WITH DE NOVO B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA IN A SINGLE CENTER

EHA Library, Mireia Camós, 132415

COMBINED BLINATUMOMAB + DASATINIB/IBRUTINIB THERAPY OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS – ANTILEUKEMIC EFFECT ON THE T-HELPER AND T-REGULATORY CELLS REDUCTION BACKGROUND.

EHA Library, Andrey Sokolov, 132416

LOW EXPRESSION OF LYMPHOID ENHANCER-BINDING FACTOR-1 (LEF1) ASSOCIATES WITH POOR PROGNOSTIC FACTORS IN PEDIATRIC ACUTE LEUKEMIA

EHA Library, Mireia Camós, 132417

CHARACTERISTICS OF PONATINIB THERAPY FOR PHILADELPHIA-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA (PH+ ALL) PATIENTS IN REAL-WORLD CLINICAL PRACTICE COMPARED TO THE PACE TRIAL

EHA Library, Michael Mauro, 132418

RISK FACTORS IN PEDIATRIC T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA: A COLLABORATIVE STUDY OF THE BIOLOGICAL COMMITTEE OF THE LEUKEMIA GROUP OF THE SPANISH HEMATOLOGY AND ONCOLOGY PEDIATRIC SOCIETY

EHA Library, Mireia Camós, 132419

MANAGEMENT AND OUTCOME OF CENTRAL NERVOUS SYSTEM (CNS) INVOLVEMENT IN ACUTE LYMPHOBLASTIC LEUKEMİA (ALL): PRE AND POST TRANSPLANT

EHA Library, Pinar Ataca, 132420

NOVEL DYNAMIN2 MUTATION IN ADULT T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Zheng Ge, 132421

LONG-TERM OUTCOME OF RELAPSED ADULT PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH CONTINUOUS IMATINIB PLUS COMBINATION CHEMOTHERAPY

EHA Library, Sungnam Lim, 132422

HEMATOPOIETIC STEM CELLS CAN BE SEPARATED FROM LEUKEMIC CELLS IN A SUBGROUP OF ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS

EHA Library, Christoph Lutz, 132423

DOES TIMING OF CENTRAL VENOUS LINE REPLACEMENT MATTER DURING INDUCTION IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA?

EHA Library, Eda Ataseven, 132424

TYROSINE KINASE INHIBITORS IN PHILADELPHIA-CHROMOSOME POSITIVE ADULT ACUTE LYMPHOBLASTIC LEUKEMIA IN REAL CLINICAL PRACTICE

EHA Library, Frantisek Folber, 132425

LPS STIMULATION INDUCES ROS FORMATION, APOPTOSIS, DNA DAMAGE AND OXIDATION OF CYSTEINE RESIDUES IN FLT3-ITD POSITIVE CELL LINES RESULTING IN FLT3-TYROSINE KINASE INHIBITOR RESISTANCE

EHA Library, Christian Mueller, 132426

ANALYSIS OF SNORNA EXPRESSION AND FUNCTION IN ACUTE MYELOID LEUKEMIA

EHA Library, Dennis Gerloff, 132427

PERSISTENCE AND EXPANSION OF HEMATOPOIETIC CLONES IN POST CHEMOTHERAPY AML ASSESED BY TARGET SEQUENCING

EHA Library, Daniela Soriano, 132428

IDENTIFICATION OF NOVEL PUTATIVE SNORNAS IN AML PATIENT SAMPLES

EHA Library, Dennis Gerloff, 132429

INHIBITION OF CXCR4 BY THE HIGH AFFINITY ANTAGONIST BL-8040 IN AML DOWNREGULATES BCL-2 THROUGH REGULATION OF MIR-15A/16-1 EXPRESSION

EHA Library, Michal Abraham, 132430

AML ORCHESTRATES MITOCHONDRIAL METABOLISM IN BONE MARROW MESENCHYMAL STROMAL CELLS THROUGH AN INCREASE OF PGC-1Α.

EHA Library, Christopher Marlein, 132431

PML-RARΑ REGULATES AKT THROUGH HSP90 INHIBITION IN APL BLASTS

EHA Library, Nélida Noguera, 132432

RUNX1-MUTATED AML SHOW A HIGH FREQUENCY OF TRISOMY 8 AND TRISOMY 13 AND ARE ASSOCIATED WITH MUTATIONS IN ASXL1 AND COMPONENTS OF THE RNA-SPLICING MACHINERY

EHA Library, Anna Stengel, 132433

REACTIVE OXYGEN SPECIES (ROS) MODULATES SENSITIVITY TO FLT3-TYROSINE KINASE INHIBITORS IN MURINE AND HUMAN FLT3-ITD POSITIVE AML CELL LINES.

EHA Library, Christian Mueller, 132434

COMBINING DOT1L INHIBITOR EPZ-5676 WITH SORAFENIB TO TREAT MLL-REARRANGED (MLL-R) PEDIATRIC ACUTE MYELOID LEUKEAMIA (AML)

EHA Library, Annalisa Lonetti, 132435

WHOLE EXOME SEQUENCING IDENTIFIES NOVEL MUTATIONS IN RELAPSED OR REFRACTORY ACUTE PROMYELOCYTIC LEUKAEMIA (APL) UNRESPONSIVE TO ORAL ARSENIC TRIOXIDE

EHA Library, Harry Gill, 132436

IMPROVING NELARABINE EFFICACY IN REFRACTORY/RELAPSED T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BY TARGETING ABERRANT PI3K/MTOR SIGNALING

EHA Library, Francesca Chiarini, 132387

ACTIVATION OF NRF2 IN BONE MARROW MESENCHYMAL STROMAL CELLS MEDIATES SURVIVAL AND CHEMOTHERAPY RESISTANCE IN ACUTE MYELOID LEUKAEMIA BLASTS

EHA Library, Niamh Loughran, 132438

MICRORNAS HSA-LET-7A AND MIR-142-3P IN T CELLS IN PATIENTS PRESENTING WITH ACUTE MYELOID LEUKAEMIA – A MEANS OF REPAIRING TUMOUR-INDUCED T CELL DEFECTS?

EHA Library, Robert Petty, 132439

TP-1287, AN ORAL PRODRUG OF THE CYCLIN-DEPENDENT KINASE-9 INHIBITOR ALVOCIDIB

EHA Library, Clifford Whatcott, 132440

POST-INDUCTION MINIMAL RESIDUAL DISEASE ASSESSMENT BY BOTH MULTIPARAMETER FLOW CYTOMETRY AND RT-PCR PREDICTS OUTCOME IN ACUTE MYELOID LEUKEMIA

EHA Library, Claire Bories, 132441

PHARMACOLOGICAL INHIBITION OF THE PI3K/AKT/MTOR AND NF-KB CANCER PROMOTING PATHWAYS FOR TARGETED TREATMENT OF ACUTE MYELOID LEUKEMIA PATIENTS

EHA Library, Andre Deslauriers, 132442

NPM1 MUTATION AND FLT3/ITD IN A DOUBLE TRANSGENIC ZEBRAFISH RECAPITULATES FEATURES OF HUMAN ACUTE MYELOID LEUKEMIA

EHA Library, Jeng-Wei Lu, 132443

THE MIR-128A/LIN28A AXIS REGULATES MYELOMONOCYTIC DIFFERENTIATION IN ACUTE MYELOID LEUKEMIA

EHA Library, Luciana De Luca, 132444

DEEP SEQUENCING OF 23 GENES DESIGNATED BY TCGA STUDY IN ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE

EHA Library, Mariam Ibañez, 132445

CD97 EXPRESSION MEDIATES MIGRATION AND ADHESION OF FLT3-ITD POSITIVE ACUTE MYELOID LEUKEMIA CELLS AND MODULATES THE BONE MARROW STROMAL MICROENVIRONMENT

EHA Library, Manja Wobus, 132446

REPOSITIONING OF QUINACRINE FOR TREATMENT OF ACUTE MYELOID LEUKEMIA - SYNERGIES AND IN VIVO EFFECTS

EHA Library, Anna Eriksson, 132447

PRIMARY ACUTE MYELOID LEUKEMIA CELLS WITH OVEREXPRESSION OF EVI-1 ARE SENSITIVE TO ALL TRANS RETINOIC ACID

EHA Library, Linda Smit, 132448

GENOME-WIDE ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM (SNPS) IN PATIENTS WITH DE NOVO ACUTE MYELOID LEUKEMIA WITH NORMAL KARYOTYPE

EHA Library, Mariam Ibañez, 132449

A NON-FUCOSYLATED FULLY HUMAN MONOCLONAL ANTIBODY AGAINST IL-3RΑ, KHK2823, SHOWS PROMISING PHARMACOLOGICAL CHARACTERISTICS IN NONCLINICAL STUDIES.

EHA Library, Tomonori Tawara, 132450

HETEROTYPIC SIGNALLING BETWEEN BONE MARROW STROMAL CELLS AND BLASTS PROVIDES INSIGHT INTO THE CELLULAR COMMUNICATION IN ACUTE MYELOID LEUKAEMIA

EHA Library, Arran Dokal, 132451

ONO-5390556 AS POTENTIAL TARGETED THERAPY FOR ACUTE MYELOID LEUKAEMIA WITH ETV6-NTRK3 FUSION GENE

EHA Library, Ryohei Kozaki, 132452

ASSESSMENT OF THE ALLELIC RATIO OF DNMT3A R882 MUTATIONS IN ACUTE MYELOID LEUKEMIA BY DIGITAL DROPLET PCR

EHA Library, Juliane Grimm, 132453

USE OF NGS MULTIGENIC PANEL IN MOLECULAR DIAGNOSTIC OF MYELOID MALIGNANCIES TO STRATIFY PATIENTS FOR PERSONALIZED THERAPIES

EHA Library, Eugenia Franchini, 132454

BIOLOGICAL MARKERS OF RELAPSE IN ELDERLY PATIENTS WITH AML IN CR AFTER INDUCTION-CONSOLIDATION CHEMOTHERAPY AND MAINTENANCE WITH 5-AZACITIDINE

EHA Library, Maria Cuzzola, 132455

PATTERNS OF INTERACTION BETWEEN MULTIPOTENT MESENCHYMAL STROMA CELLS (MSC) AND ACUTE MYELOID LEUKEMIA (AML) CELLS IN VITRO AND IN VIVO

EHA Library, Roland Schelker, 132456

THE ROLE OF THE NUCELOPHOSMIN-1 SPLICE VARIANT R2 IN ACUTE MYELOID LEUKEMIA DEVELOPMENT

EHA Library, Malgorzata Zajac, 132457

THE ROLE OF ADENOSINE DEAMINASE AND DNA METHYLATION IN ACUTE MYELOID LEUKEMIA

EHA Library, Nilgun Tekin-Bubenheim, 132458

NEW DELETION OF JAK2 DETECTED BY SNP ARRAY IN ACUTE MYELOID LEUKEMIA: A ROLE IN OVERALL SURVIVAL

EHA Library, Viviana Guadagnuolo, 132459

PHASE 1B/2 STUDY OF VENETOCLAX WITH LOW-DOSE CYTARABINE IN TREATMENT-NAÏVE PATIENTS AGED ≥65 YEARS WITH ACUTE MYELOGENOUS LEUKEMIA

EHA Library, Andrew H Wei, 132460

CLINICAL OUTCOME AND EFFECT OF ALLO-SCT IN ADULT PATIENTS WITH DE NOVO OR AML-RELATED MYELOID SARCOMA. RESULTS FROM AN ITALIAN MULTICENTER SURVEY.

EHA Library, Davide Lazzarotto, 132461

OVEREXPRESSION OF ADAM28 ENHANCES ACUTE MYELOID LEUKEMIC CELL MIGRATION AND INCREASES THE GROWTH OF XENOGRAFT TUMOURS IN MICE

EHA Library, Xiaohui Zhang, 132462

FLOW CYTOMETRY OF CEREBROSPINAL FLUID IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA AT DIAGNOSIS AND RELAPSE

EHA Library, Maria Gabelli, 132410

INTENSIVE VS. SEMI-INTENSIVE CHEMOTHERAPY IN OLDER ADULTS (55-65 YR) WITH PHILADELPHIA CHROMOSOME-NEGATIVE ACUTE LYMPHOBLASTIC LEUKEMIA.

EHA Library, Josep-Maria Ribera, 132409

PHASE I STUDY OF MOXETUMOMAB PASUDOTOX IN ADULT PATIENTS WITH RELAPSED OR REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Farhad Ravandi-Kashani, 132408

DETAILED CHARACTERIZATION OF LAIP PROFILE AND HETEROGENEITY AT TIME OF DIAGNOSIS PREDICTS MINIMAL RESIDUAL DISEASE IN B-CELL PRECURSOR ALL

EHA Library, Signe Modvig, 132407

KPT-8602 IS A SECOND-GENERATION XPO1 INHIBITOR WITH IMPROVED IN VIVO TOLERABILITY AND POTENT IN VIVO ACTIVITY AGAINST ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Jolien De Bie, 132406

SERIAL MONITORING OF BCR-ABL BY REAL-TIME POLYMERASE CHAIN REACTION IN NEWLY DIAGNOSED PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH IMATINIB

EHA Library, Sungnam Lim, 132405

DE-ESCALATION OF INTENSITY DID NOT AFFECT THE LONG-TERM OUTCOME NEITHER IN T-ALL NOR IN BCP-ALL IF NON-INTERRUPTIVE TREATMENT IS APPLIED: RESULTS OF THE RUSSIAN ALL STUDY GROUP.

EHA Library, Elena Parovichnikova, 132404

MOLECULAR DETECTION OF ALL IN THE PERIPHERAL BLOOD IS MORE SENSITIVE THAN FLOW CYTOMETRIC ANALYSIS OF THE BONE MARROW IN PATIENTS WITH TREATMENT-RELATED HYPOCELLULARITY

EHA Library, Ilan Kirsch, 132403

NEGATIVE PRE TRANSPLANT MINIMAL RESIDUAL DISEASE, ASSESSED BY FLOW CYTOMETRY, IMPROVES OUTCOME IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA, ESPECIALLY IF CLEARENCE IS ACHIEVED EARLY DURING INDUCTION

EHA Library, Massimiliano Gambella, 132402

IL7R OVEREXPRESSION IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): PROGNOSTIC IMPLICATIONS IN B-LINEAGE ALL WITHOUT RECURRENT FUSION TRANSCRIPTS

EHA Library, Valentina Gianfelici, 132401

ABNORMAL EXPRESSION OF THE CYSTEINE AND GLYCINE-RICH PROTEIN 2 GENE IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Shu-Juan Wang, 132400

DROPLET DIGITAL PCR ANALYSIS FOR DIAGNOSIS AND MINIMAL RESIDUAL DISEASE MONITORING IN ADULT PH+ ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Francesco ALBANO, 132399

OVEREXPRESSION OF PTP4A3 IN ETV6-RUNX1 ACUTE LEUKEMIA

EHA Library, Toni Grönroos, 132398

CALCINEURIN COMPLEX ISOLATED FROM T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (T-ALL) CELLS IDENTIFIES NEW SIGNALING PATHWAYS WHOSE INHIBITION SYNERGIZE WITH CALCINEURIN INHIBITION TO PROMOTE T-ALL CELL DEATH

EHA Library, Erich Piovan, 132397

DIFFERENT PROGNOSTIC ROLE OF RECURRENT COPY NUMBER ABERRATIONS IN B-LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA WITHOUT RECURRENT FUSION GENES IN 3 CONSECUTIVE AGE COHORTS

EHA Library, Monica Messina, 132396

SLOWER EARLY RESPONSE TO TREATMENT AND DISTINCT EXPRESSION PROFILE OF CHILDHOOD HIGH HYPERDIPLOID ACUTE LYMPHOBLASTIC LEUKAEMIA WITH DNA INDEX <1.16

EHA Library, Jan Zuna, 132395

IDENTIFICATION OF THE GENOMIC AND TRANSCRIPTOMIC CHANGES CORRELATED WITH THE EX VIVO RESISTANCE TO DAUNORUBICIN AND DOXORUBICIN IN PEDIATRIC ACUTE LEUKEMIAS

EHA Library, Joanna Laskowska, 132394

INFANT T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA SHOWS CHARACTERISTIC GENETIC FEATURES COMPARED TO CHILDHOOD CASES

EHA Library, Jessica Hoell, 132393

IDELALISIB SENSITIVITY AND MECHANISMS OF DISEASE PROGRESSION IN RELAPSED TCF3-PBX1 ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Samuli Eldfors, 132392

CHARACTERISATION OF JAK3 KINASE DOMAIN MUTANTS

EHA Library, Sandrine Degryse, 132391

THE WEE1 INHIBITION DEEPLY SENSITIZES ACUTE LYMPHOBLASTIC LEUKEMIA CELL LINES AND PRIMARY CELLS TO THE CYTOTOXIC EFFECT OF DIFFERENT ANTINEOPLASTIC COMPOUNDS

EHA Library, Andrea Ghelli Luserna Di Rora, 132390

DYNAMICS OF EARLY RESPONSE TO TREATMENT OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA IS ASSOCIATED WITH GENE DEFECTS

EHA Library, Agata Pastorczak, 132389

ROLE OF G9A AND EPIGENETIC CHANGES IN LEUKEMIA CELL MIGRATION AND THEIR REGULATION BY VLA4 INTEGRIN.

EHA Library, Javier Redondo Munoz, 132388

MOLECULAR LANDSCAPE OF PRIMARY AND RELAPSED ACUTE PROMYELOCYTIC LEUKEMIA

EHA Library, Annette Fasan, 132437