Autoimmunity checkpoints as therapeutic targets in B-cell malignancies

EHA Library, Markus MUSCHEN, 219183

José Carreras Award lecture: Research challenges and therapeutic perspectives in APL

EHA Library, Francesco Lo Coco, 219182

Jean Bernard Lifetime Achievement Award: Lecture

EHA Library, Charlotte Niemeyer, 219180

ATEZOLIZUMAB PLUS R-CHOP SHOWS ENCOURAGING ACTIVITY AND ACCEPTABLE TOXICITY IN PREVIOUSLY UNTREATED PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL): AN INTERIM ANALYSIS OF A PHASE I/II STUDY

EHA Library, Anas Younes, 214450

A NOVEL BAEVRLESS-PSEUDOTYPED GLOBIN LENTIVIRAL VECTOR DRIVES HIGH AND STABLE FETAL HEMOGLOBIN EXPRESSION IMPROVING THALASSEMIC ERYTHROPOIESIS IN VITRO

EHA Library, Nicholas P Anagnou, 214460

RECENT PROGRESS IN GENE THERAPY FOR SEVERE SICKLE CELL DISEASE: UPDATED INTERIM RESULTS FROM A PHASE 1 CLINICAL STUDY OF LENTIGLOBIN GENE THERAPY

EHA Library, Julie Kanter, 214456

A PHASE 2 STUDY TO ASSESS THE SAFETY AND EFFICACY OF UMBRALISIB (TGR-1202) IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) WHO ARE INTOLERANT TO PRIOR BTK OR PI3K DELTA INHIBITOR THERAPY

EHA Library, Anthony R. Mato, MD, 214453

ESTABLISHMENT OF A SIMPLE RISK SCORE TO PREDICT SYSTEMIC MASTOCYTOSIS (SM) IN ADULT PATIENTS WITH MASTOCYTOSIS IN THE SKIN (MIS)

EHA Library, David Fuchs, 214527

EVIDENCE FOR INTERCLONAL TUMOR COOPERATIVITY IN MEDIATING IBRUTINIB RESISTANCE BY BTK-C481SER EXPRESSING MYD88 MUTATED LYMPHOMA CELLS

EHA Library, Guang Yang, 214536

RAS MUTATIONS ARE THE DOMINANT MECHANISM OF SECONDARY RESISTANCE TO GILTERITINIB THERAPY FOR RELAPSED/REFRACTORY FLT3-MUTATED AML

EHA Library, Christine M McMahon, 214486

THE ROLE OF DONOR CLONAL HEMATOPOIESIS IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

EHA Library, Mareike Frick, 214494

THE RIBOSOMAL RPL10 R98S MUTATION DRIVES IRES-DEPENDENT BCL-2 TRANSLATION IN T-ALL

EHA Library, Kim Kampen, 214606

PULMONARY EMBOLISM SEVERITY INDEX (PESI) SCORE AS A PREDICTOR FOR READMISSION IN ACUTE PULMONARY EMBOLISM IN EMERGENCY DEPARTMENT?

EHA Library, Dwip Prajapati, 214608

CART19-BE-01: A EUROPEAN ACADEMIC TRIAL ON THE USE OF ARI-0001 CELLS (A3B1:CD8:4-1BB:CD3Z CAR19 CELLS) IN PATIENTS WITH CD19+ RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Julio Delgado, 214539

IMPAIRMENT OF THE MESENCHYMAL STROMAL NICHE OF BETA-THALASSEMIA PATIENTS: IMPLICATIONS OF PROLONGED IRON EXPOSURE

EHA Library, Stefania Crippa, 214459

ADDING POLATUZUMAB VEDOTIN (POLA) TO BENDAMUSTINE AND RITUXIMAB (BR) TREATMENT IMPROVES SURVIVAL IN PATIENTS WITH RELAPSED/REFRACTORY DLBCL: RESULTS OF A PHASE 2 CLINICAL TRIAL

EHA Library, Laurie Sehn, 214489

A PHASE IB/II STUDY OF DUVELISIB IN COMBINATION WITH FCR (DFCR) FOR FRONTLINE THERAPY OF YOUNGER CLL PATIENTS

EHA Library, Matthew Davids, 214523

PATIENTS’ ABILITY TO INDUCE APOPTOSIS IN MSC PREDICTS CLINICAL RESPONSES IN GRAFT-VERSUS-HOST DISEASE

EHA Library, Antonio Galleu, 214530

COMPREHENSIVE SCREENING OF B-OTHER ADULT ALL PATIENTS TREATED ON UKALL14 ESTIMATES FREQUENCY AND PROGNOSTIC IMPACT OF GENE ALTERATIONS AND IDENTIFIES JAK-STAT ABNORMALITIES AS MARKERS OF POOR OUTCOME.

EHA Library, Anthony Moorman, 214532

A SYSTEMATIC REVIEW OF PREDICTORS OF VENOUS THROMBOEMBOLISM IN ACUTE LEUKEMIA

EHA Library, Alejandro Lazo-Langner, 214541

INVESTIGATING THE ROLE OF INPP4B AS A THERAPEUTIC TARGET IN AML

EHA Library, John Woolley, 214604

PHASE 2 STUDY OF RUXOLITINIB IN COMBINATION WITH 5-AZACITIDINE IN PATIENTS WITH MYELOFIBROSIS

EHA Library, Lucia Masarova, 214526

REFINING DIFFUSE LARGE B CELL LYMPHOMA SUBGROUPS USING INTEGRATED ANALYSIS OF MULTI-LEVEL MOLECULAR PROFILES IN A PROSPECTIVE COHORT: A LYSA STUDY

EHA Library, Sydney Dubois, 214535

LONG-TERM OUTCOME OF A COHORT OF ELDERLY ACUTE MYELOID LEUKEMIA PATIENTS, NOT ELIGIBLE FOR ALLOGENEIC STEM CELL TRANSPLANTATION, INFUSED WITH ALLOREACTIVE NATURAL-KILLER CELLS AS CONSOLIDATION THERAPY

EHA Library, Sarah Parisi, 214538

EFFECT OF COVARIATES IN THE PHARMACOKINETIC/PHARMACODYNAMIC MODEL OF ANDEXANET ALFA USED TO PREDICT THE REGIMEN FOR REVERSAL OF ANTICOAGULATION BY FXA INHIBITORS IN PATIENTS WITH ACUTE MAJOR BLEEDING

EHA Library, Janet M. Leeds, 214457

PIM1 INHIBITION EFFECTIVELY ENHANCES AMD3100-INDUCED HSC MOBILIZATION

EHA Library, Tony Müller, 214529

IBRUTINIB LEAD-IN FOLLOWED BY VENETOCLAX IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA: PHASE 2 CAPTIVATE EARLY SAFETY AND EFFICACY RESULTS

EHA Library, Paolo Ghia, 214522

HIGH RECURRENCE OF FUSION GENES IN PHILADELPHIA-LIKE CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Grazia Fazio, 214454

THE EUTOS LONG-TERM SURVIVAL (ELTS) SCORE IS SUPERIOR TO THE SOKAL SCORE FOR PROGNOSIS OF SURVIVAL PROBABILITIES OF PATIENTS WITH CHRONIC-PHASE CHRONIC MYELOID LEUKAEMIA

EHA Library, Markus Pfirrmann, 214525

IMPROVEMENTS IN HEMOGLOBIN, QUALITY OF LIFE, AND SIX-MINUTE-WALK DISTANCE IN ADULTS WITH Β-THALASSEMIA TREATED WITH LUSPATERCEPT: LONG-TERM PHASE 2 STUDY

EHA Library, Antonio Piga, 214458

AXICABTAGENE CILOLEUCEL (AXI-CEL) IN PATIENTS WITH REFRACTORY LARGE B CELL LYMPHOMA: OUTCOMES BY PRIOR LINES OF THERAPY IN ZUMA-1

EHA Library, Olalekan O. Oluwole, 214449

EFFICACY OF VENETOCLAX AS A SINGLE AGENT AND IN COMBINATION WITH IBRUTINIB IN REFRACTORY OR RELAPSED T-PROLYMPHOCYTIC LEUKEMIA

EHA Library, Christoph Kornauth, 214534

PAX5-ELN ONCOPROTEIN PROMOTES MULTISTEP B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN MICE

EHA Library, Cyril Broccardo, 214531

MICRORNA-155 (MIR-155) INHIBIT T LYMPHOCYTE PRENYLATION TO PROTECT AGAINST ACUTE GRAFT VERSUS HOST DISEASE (AGVHD)

EHA Library, Xiaoxiao Wang, 214528

LENTIGLOBIN GENE THERAPY FOR TRANSFUSION-DEPENDENT Β-THALASSEMIA (TDT) IN PATIENTS WITH NON-Β0/Β0 GENOTYPES: UPDATED RESULTS FROM NORTHSTAR-2

EHA Library, Franco Locatelli, 214455

ARRAYED MOLECULAR BARCODING IDENTIFIES TNFSF13 AS A POSITIVE REGULATOR OF ACUTE MYELOID LEUKEMIA-INITIATING CELLS

EHA Library, Marion Chapellier, 214603

CHOICES: A RANDOMIZED PHASE II TRIAL FOR IMATINIB VS HYDROXYCHLOROQUINE PLUS IM FOR PATIENTS WITH CML IN MCYR WITH RESIDUAL DISEASE DETECTABLE BY Q-PCR

EHA Library, Gillian Horne, 214490

HEPCIDIN MIMETIC PTG-300 FOR TREATMENT OF INEFFECTIVE ERYTHROPOIESIS AND CHRONIC ANEMIA IN HEMOGLOBINOPATHY DISEASES

EHA Library, Greg Bourne, 214543

HIGH, DURABLE MINIMAL RESIDUAL DISEASE (MRD) NEGATIVITY WITH VENETOCLAX + RITUXIMAB IN RELAPSED/REFRACTORY CLL: MRD KINETICS AND RESPONSES IN CYTOGENETIC RISK GROUPS IN PTS FROM PHASE 3 MURANO STUDY

EHA Library, Peter Hillmen, 214452

UPDATED SAFETY & LONG TERM CLINICAL OUTCOMES IN TRANSCEND NHL 001, PIVOTAL TRIAL OF LISOCABTAGENE MARALEUCEL (JCAR017) IN R/R AGGRESSIVE NHL

EHA Library, Jeremy Abramson, 214448

COMPLEMENT C3 AND C4 ARE ASSOCIATED WITH POSTNATAL VENOUS THROMBOSIS

EHA Library, Anders Erik Astrup Dahm, 214540

HIGH RATE OF COMPLETE RESPONSE BUT MINIMAL RESIDUAL DISEASE STILL DETECTABLE AFTER FIRST-LINE TREATMENT COMBINING OBINUTUZUMAB AND IBRUTINIB IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): ICLL07 FILO TRIAL

EHA Library, Pierre Feugier, 214451

SYNTHETIC LETHAL SCREENING IDENTIFIES CHK1 INHIBITION AS AN EXPLOITABLE VULNERABILITY IN EZH2 DEFICIENT T-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA

EHA Library, Theresa Elizabeth Leon, 214495

REDUCED FIBROBLASTIC RETICULAR CELL EXPRESSION OF TISSUE-RESTRICTED ANTIGENS IMPAIRS PERIPHERAL REGULATION OF SELF-REACTIVE T CELLS DURING ACUTE GRAFT-VERSUS-HOST DISEASE

EHA Library, Simone Dertschnig, 214605

LUSPATERCEPT INHIBITS PSMAD2/3 SIGNALING AND PROMOTES ERYTHROID MATURATION THROUGH A GATA1 DEPENDENT MECHANISM

EHA Library, Pedro Martinez, 214542

IL1RAP POTENTIATES MULTIPLE ONCOGENIC SIGNALING PATHWAYS IN AML

EHA Library, Kelly Mitchell, 214602

PLATELET ADHESION UNDER FLOW CONDITION IS SIGNIFICANTLY AFFECTED BY HEMATOCRIT LEVELS IN POLYCYTHEMIA VERA PATIENTS

EHA Library, Sara Gamba, 214607

EFFICACY AND SAFETY OF CD22-DIRECTED CAR-T CELL THERAPY IN 15 PEDIATRIC REFRACTORY OR RELAPSED B ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS.

EHA Library, Jing Pan, 214537

AN UPDATED ANALYSIS OF JULIET, A GLOBAL PIVOTAL PHASE 2 TRIAL OF TISAGENLECLEUCEL IN ADULT PATIENTS WITH RELAPSED OR REFRACTORY (R/R) DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL)

EHA Library, Peter Borchmann, 214521

TH17 CELLS IN CLASSICAL HODGKIN LYMPHOMA ARE SUPPRESSED VIA THE PD1-PDL1 AXIS AND MAY PLAY AN IMPORTANT ROLE IN THE ACTION OF PD1 CHECKPOINT INHIBITORS

EHA Library, Joseph Taylor, 214533

FINAL RESULTS OF THE DESTINY STUDY OF DE-ESCALATION AND STOPPING TREATMENT IN CHRONIC MYELOID LEUKAEMIA

EHA Library, Richard Clark, 214524

CAR T cell therapies for cancer

EHA Library, Carl June, 219172

New strategies for relapsed/refractory Hodgkin lymphoma

EHA Library, John Kuruvilla, 219160

Molecular profiling in myeloma

EHA Library, Faith E. Davies, 219161

Immunotherapy in myeloma: Why, when and how?

EHA Library, Niels W. C. J. van de donk, 219162

Optimal sequencing in the management of relapsed/refractory myeloma patients

EHA Library, Philippe Moreau, 219163

Education session - MM: Chair

EHA Library, Michel Delforge, 219164

Inherited predisposition to MDS/AML

EHA Library, Jude FITZGIBBON, 219166

Recent developments in immunotherapy in AML

EHA Library, Marion Subklewe, 219167

PROs in solid tumours and hematological malignancies: How different are they?

EHA Library, Pushpendra Goswami, 219176

Regulatory authority guidelines for development and use of PRO instruments

EHA Library, Tatyana Ionova, 219175

Pathogenesis of cancer-associated thrombosis

EHA Library, Nigel Mackman, 219396

Clinical prediction scores for venous thromboembolism in patients with a hematological malignancy

EHA Library, Nick van Es, 219397

Cancer-associated thrombosis - Which lessons for the hematologist?

EHA Library, Simon Noble, 219398

Use of Patient Reported Outcomes (PRO) in hematology: Does it matter?

EHA Library, Anton Hagenbeek, 219174

Epigenetic therapy and beyond in AML

EHA Library, Andrew Wei, 219168

Optimization of the first line treatment in HD

EHA Library, Pauline Brice, 219159

Genetics of classical Hodgkin Lymphoma (cHL)

EHA Library, Enrico Tiacci, 219158

Platelets and their ability to affect innate and adaptive immunity

EHA Library, John Semple, 219155

Inherited platelet disorders caused by thrombopoietin mutations

EHA Library, Federica Melazzini, 219156

Transfusion in patients with acute major blood loss: Evidence when, for whom and what products are best

EHA Library, JJ Zwaginga, 219152

Potential perils of iron supplementation in low income countries

EHA Library, Andrew Prentice, 219149

Iron-sulfur protein biogenesis in health and disease

EHA Library, Roland Lill, 219147

Preventing relapse of transplant

EHA Library, Charles Craddock, 219145

Clinical implications of minimal residual disease

EHA Library, Jan Cornelissen, 219144

Methods to detect minimal residual disease

EHA Library, Torsten Haferlach, 219143

Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy

EHA Library, Marc Maegele, 219151

Clinical and laboratory evaluation of acute blood loss and hemorrhagic shock

EHA Library, Augusto Federici, 219150

Congenital sideroblastic anemia: Iron and heme lost in mitochondrial translation

EHA Library, Mark Fleming, 219148

From antibiotics to ibrutinib: An array of treatment modalities

EHA Library, Catherine Thieblemont, 219141

Deregulation of cell signaling in marginal zone lymphoma

EHA Library, Ming Qing Du, 219139

Marginal zone lymphoma: Differentiation among pathologically challenging entities

EHA Library, Maurilio Ponzoni, 219140

Current role of chemotherapy free drug combinations for chronic lymphocytic leukemia

EHA Library, Michael Hallek, 219095

Translating genetic and epigenetic knowledge into clinical utility

EHA Library, Richard Rosenquist Brandell, 219094

Pathogenesis of CLL: the view from the lymph node

EHA Library, Adrian Wiestner, 219093

TARGETING WNT10B*R-MEDIATED AUTOCRINE WNT SIGNALING ACTIVATION IN ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Adriana Cassaro, 214663

CIRCULAR RNAOME VARIATION IN NORMAL HEMATOPOIESIS AND MLL REARRANGED ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Stefania Bortoluzzi, 214658

COMBINATORIAL CSF3R AND RUNX1 MUTATIONS INVOLVED IN THE LEUKEMIC PROGRESSION OF SEVERE CONGENITAL NEUTROPENIA CONFER A G-CSF-DEPENDENT PREMALIGNANT STATE IN MICE TERMINATING IN G-CSF INDEPENDENT AML

EHA Library, Patricia Olofsen, 214649

NOVEL PROGNOSTIC MARKER ARID5B LOW EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Chunhua song, 214665

MIR-451 IS A NEW BIOMARKER THAT IDENTIFIES ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS WHO MAY BENEFIT FROM TREATMENT WITH NAMPT INHIBITORS

EHA Library, Keren shichrur, 214664

INTEGRATIVE ANALYSIS OF GENOMIC DATA REPOSITIONS THE USE OF 5’-AZACYTIDINE AND DECITABINE IN BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM TREATMENT

EHA Library, Maria Rosaria Sapienza, 214630

LOSS OF TET2 FOLLOWED BY ACQUISITION OF ACTIVATING KRAS MUTATION LEADS TO COOPERATIVE MALIGNANT MYELOPROLIFERATION THROUGH AMPLIFICATION OF RAS SIGNALING IN A DOSE- AND TIME-DEPENDENT MANNER

EHA Library, Matthew Miller, 214631

DEHYDROPEPTIDASE 1 ENHANCED THE GROWTH AND SURVIVAL OF LEUKEMIA CELLS IN VIVO AND IDENTIFIED A HIGH RISK OF RELAPSE IN PATIENTS WITH COMMON B-CELL ALL

EHA Library, Jiamin Zhang, 214662

5-AZACYTIDINE ENHANCES THE ANTI-LEUKEMIC ACTIVITIY OF IDH1 INHIBITOR BAY 1436032 IN VIVO IN IDH1 MUTANT ACUTE MYELOID LEUKEMIA

EHA Library, Anuhar Chaturvedi, 214632

EPIGENOMIC ANALYSIS REVEALS STEM CELL-LIKE RELAPSE SIGNATURE IN PEDIATRIC ACUTE MYELOID LEUKEMIA

EHA Library, Caroline Wiggers, 214648

NOVEL TARGETED THERAPIES FOR RESISTANT CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Sanil BHATIA, 214661

ENHANCED EFFICACY OF THE SYK INHIBITOR ENTOSPLETINIB AND VINCRISTINE IN KMT2A-REARRANGED ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Sarah Tasian, 214660

CDK8 DEGRADATION - PREPARING THE GROUND FOR MTOR INHIBITION IN BCR/ABL+ ALL

EHA Library, Ingeborg Menzl, 214657

INTEGRATED GENETIC AND EPIGENETIC ANALYSIS ELUCIDATED EXPRESSION AND METHYLATION PROFILES OF ACUTE LYMPHOBLASTIC LEUKEMIA IN DOWN SYNDROME

EHA Library, Yasuo Kubota, 214659

IDENTIFYING NEW DISEASE GENES IN FAMILIAL MYELODYSPLASIA/ACUTE MYELOID LEUKEMIA

EHA Library, Ana RIO-MACHIN, 214650