NLRP3 INFLAMMSOME ACTIVATION IN PBMCS CONTROLS THE T CELL RESPONSE IN ADULT PATIENTS WITH CHRONIC IMMUNE THROMBOCYTOPENIA

EHA Library, Mingqiang Hua, 214617

MODELING HIGH RISK ACUTE LEUKEMIA WITH COMBINED T-CELL AND MYELOID PHENOTYPE CAUSED BY THE ETV6-NCOA2 FUSION GENE

EHA Library, Hila Fishman, 214609

PANOBINOSTAT, DECITABINE, AND DONOR LYMPHOCYTE INFUSION POST ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: THE HOVON 116 STUDY IN NEWLY DIAGNOSED POOR-RISK AML PATIENTS

EHA Library, Jan Cornelissen, 214550

REGULATION OF HIF-1Α IN TP53 DISRUPTED CHRONIC LYMPHOCYTIC LEUKEMIA CELLS AND ITS POTENTIAL ROLE AS A THERAPEUTIC TARGET

EHA Library, Marta Coscia, 214468

GRAFT-VERSUS-LEUKEMIA EFFECTS IN SECONDARY ACUTE MYELOID LEUKEMIA: A RETROSPECTIVE STUDY FROM THE ACUTE LEUKEMIA WORKING PARTY OF THE EBMT

EHA Library, Frederic Baron, 214556

DELETION OF STAT2 INCREASES THROMBOCYTOSIS AND SURVIVAL IN A JAK2 V617F MOUSE MODEL OF MPN VIA A NON CELL-AUTONOMOUS MECHANISM.

EHA Library, Gaëlle Vertenoeil, 214559

LIVER IRON CONTENT DETERMINES HEPCIDIN LEVELS

EHA Library, Sandro Altamura, 214564

EZH2 AND RUNX1 MUTATIONS COLLABORATE TO INITIATE DISTINCT HEMATOLOGICAL MALIGNANCIES DEPENDING ON THE TARGET CELL

EHA Library, Christopher Booth, 214614

INVESTIGATING THE ROLE OF NCOA4 IN ACUTE AND CHRONIC IRON RELEASE FROM STORES

EHA Library, Antonella Nai, 214563

INTRINSIC DEFECTS CAUSED BY COMBINED CSNK1A1/RPS14 AND MIRNA145/146A DEFICIENCY DIRECTLY ALTER THE MICROENVIRONMENT IN A NOVEL MOUSE MODEL FOR DEL(5Q) MDS

EHA Library, Flavia Ribezzo, 214613

PIGGYBAC TRANSPOSON SCREENING IDENTIFIES NOVEL CANCER GENES AND REGULATORY ELEMENTS IN T CELL LEUKEMIA

EHA Library, Anja Pfaus, 214552

OPTIMISMM: PHASE 3 TRIAL OF POMALIDOMIDE, BORTEZOMIB, AND LOW‐DOSE DEXAMETHASONE VS BORTEZOMIB AND LOW-DOSE DEXAMETHASONE IN LENALIDOMIDE-EXPOSED PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA

EHA Library, Paul Richardson, 214461

ADMINISTRATION OF BPX-501 CELLS FOLLOWING ALPHA/BETA T-CELL AND B-CELL-DEPLETED HLA HAPLOIDENTICAL HSCT (HAPLO-HSCT) IN CHILDREN WITH PRIMARY IMMUNODEFICIENCIES

EHA Library, Daria Pagliara, 214469

MULTIPLE MECHANISMS OF KRAS ACTIVATION IN TRISOMY 12 CHRONIC LYMPHOCYTIC LEUKEMIA

EHA Library, Elena Vendramini, 214612

PROSPECTIVE STUDY OF HLA-MATCHED DONOR AVAILABILITY AND SURVIVAL IN REMISSION AFTER AML IN OLDER ADULTS: 1ST PLANNED ANALYSIS FROM ECOG-ACRIN E2906 PHASE III RANDOMIZED TRIAL IN PATIENTS AGE ≥60 YEARS

EHA Library, James M Foran, 214549

MULTINATIONAL, RANDOMIZED PHASE 3 TRIAL OF IBRUTINIB-RITUXIMAB VS PLACEBO-RITUXIMAB IN PATIENTS WITH WALDENSTRÖM’S MACROGLOBULINEMIA.

EHA Library, Meletios Dimopoulos, 214546

A NOVEL INHIBITORY MUTATION FOR JAK2 V617F TARGETING THE AROMATIC INTERACTION AROUND F617 RESTORES NORMAL FUNCTION FOR MOST OF JAK2-UTILIZING CYTOKINE RECEPTORS EXCEPT IFNGR

EHA Library, Emilie Leroy, 214615

A STRATEGY WITH CHAPERONE-LIKE COMPOUNDS TO RESTORE EXPRESSION OF FACTOR IX VARIANTS AFFECTED BY FREQUENT MISSENSE MUTATIONS CAUSING HEMOPHILIA B

EHA Library, Mirko Pinotti, 214561

Future challenges in prevention and treatment of venous thrombosis

EHA Library, John-Bjarne Hansen, 219192

Non-intensive treatment strategies in AML

EHA Library, Gert Ossenkoppele, 219195

Intensive chemotherapy regimens in acute myeloide leukemia

EHA Library, Je-Hwan Lee, 219196

Time trends in incidence rates of venous thrombosis

EHA Library, Sigrid Braekkan, 219191

Toxicity in hematologic malignancies: Considerations in bone marrow transplant, survivors and real world hematology patients

EHA Library, John Gribben, 219189

Using patient-reported outcomes to improve toxicity assessment

EHA Library, Fabio Efficace, 219188

The imperative for change in adverse event reporting in hematologic malignancies

EHA Library, Gita Thanarajasingam, 219187

CART cells

EHA Library, Franco Locatelli, 219186

Bispecific antibodies for ALL

EHA Library, C Peters, 219185

QUIZARTINIB SIGNIFICANTLY PROLONGS OVERALL SURVIVAL IN PATIENTS WITH FLT3-INTERNAL TANDEM DUPLICATION–MUTATED (MUT) RELAPSED/REFRACTORY AML IN THE PHASE 3, RANDOMIZED, CONTROLLED QUANTUM-R TRIAL

EHA Library, Jorge Cortes, 218882

Jean Bernard Lifetime Achievement Award: Lecture

EHA Library, Charlotte Niemeyer, 219180

José Carreras Award lecture: Research challenges and therapeutic perspectives in APL

EHA Library, Francesco Lo Coco, 219182

Autoimmunity checkpoints as therapeutic targets in B-cell malignancies

EHA Library, Markus MUSCHEN, 219183

PULMONARY EMBOLISM SEVERITY INDEX (PESI) SCORE AS A PREDICTOR FOR READMISSION IN ACUTE PULMONARY EMBOLISM IN EMERGENCY DEPARTMENT?

EHA Library, Dwip Prajapati, 214608

ESTABLISHMENT OF A SIMPLE RISK SCORE TO PREDICT SYSTEMIC MASTOCYTOSIS (SM) IN ADULT PATIENTS WITH MASTOCYTOSIS IN THE SKIN (MIS)

EHA Library, David Fuchs, 214527

EVIDENCE FOR INTERCLONAL TUMOR COOPERATIVITY IN MEDIATING IBRUTINIB RESISTANCE BY BTK-C481SER EXPRESSING MYD88 MUTATED LYMPHOMA CELLS

EHA Library, Guang Yang, 214536

THE ROLE OF DONOR CLONAL HEMATOPOIESIS IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

EHA Library, Mareike Frick, 214494

RAS MUTATIONS ARE THE DOMINANT MECHANISM OF SECONDARY RESISTANCE TO GILTERITINIB THERAPY FOR RELAPSED/REFRACTORY FLT3-MUTATED AML

EHA Library, Christine M McMahon, 214486

A NOVEL BAEVRLESS-PSEUDOTYPED GLOBIN LENTIVIRAL VECTOR DRIVES HIGH AND STABLE FETAL HEMOGLOBIN EXPRESSION IMPROVING THALASSEMIC ERYTHROPOIESIS IN VITRO

EHA Library, Nicholas P Anagnou, 214460

RECENT PROGRESS IN GENE THERAPY FOR SEVERE SICKLE CELL DISEASE: UPDATED INTERIM RESULTS FROM A PHASE 1 CLINICAL STUDY OF LENTIGLOBIN GENE THERAPY

EHA Library, Julie Kanter, 214456

A PHASE 2 STUDY TO ASSESS THE SAFETY AND EFFICACY OF UMBRALISIB (TGR-1202) IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) WHO ARE INTOLERANT TO PRIOR BTK OR PI3K DELTA INHIBITOR THERAPY

EHA Library, Anthony R. Mato, MD, 214453

ATEZOLIZUMAB PLUS R-CHOP SHOWS ENCOURAGING ACTIVITY AND ACCEPTABLE TOXICITY IN PREVIOUSLY UNTREATED PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL): AN INTERIM ANALYSIS OF A PHASE I/II STUDY

EHA Library, Anas Younes, 214450

THE RIBOSOMAL RPL10 R98S MUTATION DRIVES IRES-DEPENDENT BCL-2 TRANSLATION IN T-ALL

EHA Library, Kim Kampen, 214606

COMPREHENSIVE SCREENING OF B-OTHER ADULT ALL PATIENTS TREATED ON UKALL14 ESTIMATES FREQUENCY AND PROGNOSTIC IMPACT OF GENE ALTERATIONS AND IDENTIFIES JAK-STAT ABNORMALITIES AS MARKERS OF POOR OUTCOME.

EHA Library, Anthony Moorman, 214532

PATIENTS’ ABILITY TO INDUCE APOPTOSIS IN MSC PREDICTS CLINICAL RESPONSES IN GRAFT-VERSUS-HOST DISEASE

EHA Library, Antonio Galleu, 214530

REFINING DIFFUSE LARGE B CELL LYMPHOMA SUBGROUPS USING INTEGRATED ANALYSIS OF MULTI-LEVEL MOLECULAR PROFILES IN A PROSPECTIVE COHORT: A LYSA STUDY

EHA Library, Sydney Dubois, 214535

PHASE 2 STUDY OF RUXOLITINIB IN COMBINATION WITH 5-AZACITIDINE IN PATIENTS WITH MYELOFIBROSIS

EHA Library, Lucia Masarova, 214526

CART19-BE-01: A EUROPEAN ACADEMIC TRIAL ON THE USE OF ARI-0001 CELLS (A3B1:CD8:4-1BB:CD3Z CAR19 CELLS) IN PATIENTS WITH CD19+ RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Julio Delgado, 214539

A SYSTEMATIC REVIEW OF PREDICTORS OF VENOUS THROMBOEMBOLISM IN ACUTE LEUKEMIA

EHA Library, Alejandro Lazo-Langner, 214541

A PHASE IB/II STUDY OF DUVELISIB IN COMBINATION WITH FCR (DFCR) FOR FRONTLINE THERAPY OF YOUNGER CLL PATIENTS

EHA Library, Matthew Davids, 214523

ADDING POLATUZUMAB VEDOTIN (POLA) TO BENDAMUSTINE AND RITUXIMAB (BR) TREATMENT IMPROVES SURVIVAL IN PATIENTS WITH RELAPSED/REFRACTORY DLBCL: RESULTS OF A PHASE 2 CLINICAL TRIAL

EHA Library, Laurie Sehn, 214489

IMPAIRMENT OF THE MESENCHYMAL STROMAL NICHE OF BETA-THALASSEMIA PATIENTS: IMPLICATIONS OF PROLONGED IRON EXPOSURE

EHA Library, Stefania Crippa, 214459

INVESTIGATING THE ROLE OF INPP4B AS A THERAPEUTIC TARGET IN AML

EHA Library, John Woolley, 214604

LONG-TERM OUTCOME OF A COHORT OF ELDERLY ACUTE MYELOID LEUKEMIA PATIENTS, NOT ELIGIBLE FOR ALLOGENEIC STEM CELL TRANSPLANTATION, INFUSED WITH ALLOREACTIVE NATURAL-KILLER CELLS AS CONSOLIDATION THERAPY

EHA Library, Sarah Parisi, 214538

THE EUTOS LONG-TERM SURVIVAL (ELTS) SCORE IS SUPERIOR TO THE SOKAL SCORE FOR PROGNOSIS OF SURVIVAL PROBABILITIES OF PATIENTS WITH CHRONIC-PHASE CHRONIC MYELOID LEUKAEMIA

EHA Library, Markus Pfirrmann, 214525

IBRUTINIB LEAD-IN FOLLOWED BY VENETOCLAX IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA: PHASE 2 CAPTIVATE EARLY SAFETY AND EFFICACY RESULTS

EHA Library, Paolo Ghia, 214522

IMPROVEMENTS IN HEMOGLOBIN, QUALITY OF LIFE, AND SIX-MINUTE-WALK DISTANCE IN ADULTS WITH Β-THALASSEMIA TREATED WITH LUSPATERCEPT: LONG-TERM PHASE 2 STUDY

EHA Library, Antonio Piga, 214458

EFFECT OF COVARIATES IN THE PHARMACOKINETIC/PHARMACODYNAMIC MODEL OF ANDEXANET ALFA USED TO PREDICT THE REGIMEN FOR REVERSAL OF ANTICOAGULATION BY FXA INHIBITORS IN PATIENTS WITH ACUTE MAJOR BLEEDING

EHA Library, Janet M. Leeds, 214457

HIGH RECURRENCE OF FUSION GENES IN PHILADELPHIA-LIKE CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Grazia Fazio, 214454

AXICABTAGENE CILOLEUCEL (AXI-CEL) IN PATIENTS WITH REFRACTORY LARGE B CELL LYMPHOMA: OUTCOMES BY PRIOR LINES OF THERAPY IN ZUMA-1

EHA Library, Olalekan O. Oluwole, 214449

PIM1 INHIBITION EFFECTIVELY ENHANCES AMD3100-INDUCED HSC MOBILIZATION

EHA Library, Tony Müller, 214529

UPDATED SAFETY & LONG TERM CLINICAL OUTCOMES IN TRANSCEND NHL 001, PIVOTAL TRIAL OF LISOCABTAGENE MARALEUCEL (JCAR017) IN R/R AGGRESSIVE NHL

EHA Library, Jeremy Abramson, 214448

ARRAYED MOLECULAR BARCODING IDENTIFIES TNFSF13 AS A POSITIVE REGULATOR OF ACUTE MYELOID LEUKEMIA-INITIATING CELLS

EHA Library, Marion Chapellier, 214603

HEPCIDIN MIMETIC PTG-300 FOR TREATMENT OF INEFFECTIVE ERYTHROPOIESIS AND CHRONIC ANEMIA IN HEMOGLOBINOPATHY DISEASES

EHA Library, Greg Bourne, 214543

COMPLEMENT C3 AND C4 ARE ASSOCIATED WITH POSTNATAL VENOUS THROMBOSIS

EHA Library, Anders Erik Astrup Dahm, 214540

HIGH, DURABLE MINIMAL RESIDUAL DISEASE (MRD) NEGATIVITY WITH VENETOCLAX + RITUXIMAB IN RELAPSED/REFRACTORY CLL: MRD KINETICS AND RESPONSES IN CYTOGENETIC RISK GROUPS IN PTS FROM PHASE 3 MURANO STUDY

EHA Library, Peter Hillmen, 214452

LENTIGLOBIN GENE THERAPY FOR TRANSFUSION-DEPENDENT Β-THALASSEMIA (TDT) IN PATIENTS WITH NON-Β0/Β0 GENOTYPES: UPDATED RESULTS FROM NORTHSTAR-2

EHA Library, Franco Locatelli, 214455

CHOICES: A RANDOMIZED PHASE II TRIAL FOR IMATINIB VS HYDROXYCHLOROQUINE PLUS IM FOR PATIENTS WITH CML IN MCYR WITH RESIDUAL DISEASE DETECTABLE BY Q-PCR

EHA Library, Gillian Horne, 214490

MICRORNA-155 (MIR-155) INHIBIT T LYMPHOCYTE PRENYLATION TO PROTECT AGAINST ACUTE GRAFT VERSUS HOST DISEASE (AGVHD)

EHA Library, Xiaoxiao Wang, 214528

PAX5-ELN ONCOPROTEIN PROMOTES MULTISTEP B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN MICE

EHA Library, Cyril Broccardo, 214531

EFFICACY OF VENETOCLAX AS A SINGLE AGENT AND IN COMBINATION WITH IBRUTINIB IN REFRACTORY OR RELAPSED T-PROLYMPHOCYTIC LEUKEMIA

EHA Library, Christoph Kornauth, 214534

REDUCED FIBROBLASTIC RETICULAR CELL EXPRESSION OF TISSUE-RESTRICTED ANTIGENS IMPAIRS PERIPHERAL REGULATION OF SELF-REACTIVE T CELLS DURING ACUTE GRAFT-VERSUS-HOST DISEASE

EHA Library, Simone Dertschnig, 214605

IL1RAP POTENTIATES MULTIPLE ONCOGENIC SIGNALING PATHWAYS IN AML

EHA Library, Kelly Mitchell, 214602

PLATELET ADHESION UNDER FLOW CONDITION IS SIGNIFICANTLY AFFECTED BY HEMATOCRIT LEVELS IN POLYCYTHEMIA VERA PATIENTS

EHA Library, Sara Gamba, 214607

LUSPATERCEPT INHIBITS PSMAD2/3 SIGNALING AND PROMOTES ERYTHROID MATURATION THROUGH A GATA1 DEPENDENT MECHANISM

EHA Library, Pedro Martinez, 214542

HIGH RATE OF COMPLETE RESPONSE BUT MINIMAL RESIDUAL DISEASE STILL DETECTABLE AFTER FIRST-LINE TREATMENT COMBINING OBINUTUZUMAB AND IBRUTINIB IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): ICLL07 FILO TRIAL

EHA Library, Pierre Feugier, 214451

SYNTHETIC LETHAL SCREENING IDENTIFIES CHK1 INHIBITION AS AN EXPLOITABLE VULNERABILITY IN EZH2 DEFICIENT T-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA

EHA Library, Theresa Elizabeth Leon, 214495

AN UPDATED ANALYSIS OF JULIET, A GLOBAL PIVOTAL PHASE 2 TRIAL OF TISAGENLECLEUCEL IN ADULT PATIENTS WITH RELAPSED OR REFRACTORY (R/R) DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL)

EHA Library, Peter Borchmann, 214521

FINAL RESULTS OF THE DESTINY STUDY OF DE-ESCALATION AND STOPPING TREATMENT IN CHRONIC MYELOID LEUKAEMIA

EHA Library, Richard Clark, 214524

TH17 CELLS IN CLASSICAL HODGKIN LYMPHOMA ARE SUPPRESSED VIA THE PD1-PDL1 AXIS AND MAY PLAY AN IMPORTANT ROLE IN THE ACTION OF PD1 CHECKPOINT INHIBITORS

EHA Library, Joseph Taylor, 214533

EFFICACY AND SAFETY OF CD22-DIRECTED CAR-T CELL THERAPY IN 15 PEDIATRIC REFRACTORY OR RELAPSED B ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS.

EHA Library, Jing Pan, 214537

CAR T cell therapies for cancer

EHA Library, Carl June, 219172

Epigenetic therapy and beyond in AML

EHA Library, Andrew Wei, 219168

Recent developments in immunotherapy in AML

EHA Library, Marion Subklewe, 219167

Use of Patient Reported Outcomes (PRO) in hematology: Does it matter?

EHA Library, Anton Hagenbeek, 219174

Regulatory authority guidelines for development and use of PRO instruments

EHA Library, Tatyana Ionova, 219175

PROs in solid tumours and hematological malignancies: How different are they?

EHA Library, Pushpendra Goswami, 219176

Inherited predisposition to MDS/AML

EHA Library, Jude FITZGIBBON, 219166

Education session - MM: Chair

EHA Library, Michel Delforge, 219164

Optimal sequencing in the management of relapsed/refractory myeloma patients

EHA Library, Philippe Moreau, 219163

Immunotherapy in myeloma: Why, when and how?

EHA Library, Niels W.C.J. van de Donk, 219162

Molecular profiling in myeloma

EHA Library, Faith E. Davies, 219161

New strategies for relapsed/refractory Hodgkin lymphoma

EHA Library, John Kuruvilla, 219160

Optimization of the first line treatment in HD

EHA Library, Pauline Brice, 219159

Genetics of classical Hodgkin Lymphoma (cHL)

EHA Library, Enrico Tiacci, 219158

Pathogenesis of cancer-associated thrombosis

EHA Library, Nigel Mackman, 219396

Clinical prediction scores for venous thromboembolism in patients with a hematological malignancy

EHA Library, Nick van Es, 219397

Cancer-associated thrombosis - Which lessons for the hematologist?

EHA Library, Simon Noble, 219398

Inherited platelet disorders caused by thrombopoietin mutations

EHA Library, Federica Melazzini, 219156

Platelets and their ability to affect innate and adaptive immunity

EHA Library, John Semple, 219155

Translating genetic and epigenetic knowledge into clinical utility

EHA Library, Richard Rosenquist Brandell, 219094

Pathogenesis of CLL: the view from the lymph node

EHA Library, Adrian Wiestner, 219093