CRISPR/Cas9 genome editing, from mechanism to therapy

EHA Library, Jacob Corn, 184491

Controversies in treating small clots in the leg and in the lung

EHA Library, Sebastian Schellong, 184487

Fertility preservation in pre-pubertal and adolescent males

EHA Library, Rod Mitchell, 184479

Fertility Preservation In Female Patients

EHA Library, Marie-Madeline Dolmans, 184478

Towards clinical translation of targeted gene editing in human hematopoietic stem cells

EHA Library, Luigi Naldini, 184490

Novel aspects in the diagnostic management of deep vein thrombosis and pulmonary embolism

EHA Library, Menno Huisman, 184486

What patients expect from hematologists

EHA Library, A Plate, 184477

Targeting Mutated FLT3

EHA Library, Mark Levis, 184473

France-Belgium-Switzerland: The GRAALL Intergroup

EHA Library, Hervé Dombret, 184481

Cross-talk between inflammation and coagulation

EHA Library, Thomas Renné, 184485

Major results and future approaches of Italian ALL study groups

EHA Library, Sabina Chiaretti, 184480

The effects of chemotherapy and radiotherapy on reproduction

EHA Library, William Hamish Wallace, 184476

Molecular Diagnostics In AML

EHA Library, L Bullinger, 184472

Circulating tumor DNA in Non-Hodgkin lymphoma: Clinical and future research applications

EHA Library, Mark Roschewski, 184470

Rare bleeding disorders - Diagnosis and treatment

EHA Library, Gili Kenet, 184466

Neurological complications of sickle cell disease

EHA Library, Fenalla Kirkham, 184462

GVL And GVHD Differences And Similarities

EHA Library, Fred Falkenburg, 184458

How to treat CML in 2017

EHA Library, Andreas Hochhaus, 184454

Interim-PET as a valid biomarker for early response in malignant lymphoma; when to perform and how to assess

EHA Library, Josee Zijlstra, 184469

Do we still need bone marrow biopsies?

EHA Library, Tarec El-Galaly, 184468

Introduction EHA LyG

EHA Library, Marie Jose Kersten, 184467

Diagnosis and management of DIC and primary hyperfibrinolysis

EHA Library, Alessandro Squizzato, 184465

Iron Chelation In Hemoglobinopathies

EHA Library, Vip Viprakasit, 184461

The Role Of Intestinal Flora In Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

EHA Library, Marcel van den Brink, 184457

Molecular work up and monitoring of CML patients

EHA Library, Nick Cross, 184453

Biological and clinical relevance of fibrin clot structure

EHA Library, Nicola Mutch, 184464

Genome editing in hemoglobinopathies

EHA Library, Mitchell J. Weiss, 184460

GvHD Prophylaxis And Treatment, New Modalities

EHA Library, Robert Zeiser, 184456

Novel approaches to eradicate CML stem cells

EHA Library, Mhairi Copland, 184452

Fertility preservation in females

EHA Library, Marie-Madeline Dolmans, 192906

IDENTIFICATION OF NOVEL GENE FUSIONS IN ACUTE MYELOID LEUKEMIA WITH COMPLEX KARYOTYPE BY TRANSCRIPTOME ANALYSIS USING RNA SEQUENCING

EHA Library, Frank Rücker, 181469

H3K27ME3 LEVEL ON THE HIST1 CLUSTER: A POWERFUL EPIGENETIC BIOMARKER THAT STRATIFIES TWO GROUPS OF NPM1-MUTATED AML DIFFERING IN THEIR OUTCOME AND EXPRESSION PROFILE

EHA Library, Sylvain garciaz, 181470

FUNCTIONAL ASSESSMENT OF NOVEL DIAGNOSTIC FLT3 MUTATIONS AND INHIBITION BY KINASE INHIBITORS

EHA Library, Katherine Tarlock, 181471

THE BCL-2 INHIBITOR VENETOCLAX INHIBITS NRF2 ANTIOXIDANT PATHWAY ACTIVATION INDUCED BY HYPOMETHYLATING AGENTS IN ACUTE MYELOID LEUKEMIA

EHA Library, Le Xuan Truong, 181473

UNRAVELING EPIGENOMIC REGULATION IN THE EVOLUTION OF RELAPSING PEDIATRIC AML

EHA Library, Caroline Wiggers, 181474

MECHANISTICALLY INFORMED COMBINATIONS OF SY-1425, A POTENT AND SELECTIVE RARΑ AGONIST, WITH HYPOMETHYLATING OR ANTI-CD38 TARGETED AGENTS IN AML AND MDS

EHA Library, Michael McKeown, 181475

FLT3 INHIBITION OVERCOMES RESISTANCE TO THE BCL-2 SELECTIVE ANTAGONIST, VENETOCLAX, IN FLT3-ITD MUTANT AML MODELS

EHA Library, Deepak Sampath, 181476

SPECIFIC TARGETING OF ACUTE MYELOID LEUKEMIA STEM CELLS BY INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7

EHA Library, Linda Smit, 181477

ONGOING PHASE 2 CLINICAL TRIAL OF SL-401 IN PATIENTS WITH BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM (BPDCN): STAGE 1 AND STAGE 2 RESULTS

EHA Library, Naveen Pemmaraju, 181478

PROGNOSTIC IMPACT OF SOMATIC MUTATION CLEARANCE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

EHA Library, Koichi Takahashi, 181479

DO EDUCATION AND INCOME AFFECT TREATMENT AND OUTCOME IN ACUTE MYELOID LEUKEMIA IN A TAX-SUPPORTED HEALTH CARE SYSTEM? A DANISH NATIONAL POPULATION-BASED COHORT STUDY

EHA Library, Lene Sofie Granfeldt Østgård, 181480

IDENTIFICATION OF PATTERNS IN CO-OCCURRING MUTATIONS IN AML PATIENTS WITH GERMLINE AND SOMATIC RUNX1 MUTATIONS

EHA Library, Uma Borate, 181481

MULTIPLE LEUKEMIC STEM CELL MARKER EXPRESSION IS ASSOCIATED WITH POOR PROGNOSIS IN DE NOVO ACUTE MYELOID LEUKEMIA

EHA Library, Tomohiro Yabushita, 181483

NEXT GENERATION SEQUENCING TARGETED PANEL FOR MINIMAL RESIDUAL DISEASEMONITORING IN ACUTE MYELOID LEUKEMIA

EHA Library, Valerie McClain, 181484

IS IT POSSIBLE TO RELIABLY DETECT CLINICALLY-RELEVANT BIALLELIC CEBPA GENE MUTATIONS USING NGS PANELS?

EHA Library, Marta Fernandez-Mercado, 181485

EXPERIENCE WITH MINIMAL RESIDUAL DISEASE (MRD) MONITORING IN AML WITH RUNX1-RUNX1T1: A STUDY ON 186 PATIENTS

EHA Library, Alexander Höllein, 181486

NUMBER OF TP53 ABNORMALITIES AND THEIR CLINICAL RELEVANCE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROMES

EHA Library, Guillermo Montalban-Bravo, 181487

VADASTUXIMAB TALIRINE PLUS HYPOMETHYLATING AGENTS (HMA): A WELL-TOLERATED REGIMEN WITH HIGH REMISSION RATE IN FRONTLINE OLDER PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML)

EHA Library, Farhad Ravandi-Kashani, 181488

ACUTE MYELOID LEUKEMIA WITH INTERMEDIATE-RISK CYTOGENETICS AND A FAVORABLE GENOTYPE: PROGNOSTIC FACTORS AND RESULTS IN PATIENTS TREATED ACCORDING THE SPANISH CETLAM PROTOCOLS.

EHA Library, Jorge Sierra, 181489

GMI-1271, A POTENT E-SELECTIN ANTAGONIST, COMBINED WITH INDUCTION CHEMOTHERAPY IN ELDERLY PATIENTS WITH UNTREATED AML: A NOVEL, WELL-TOLERATED REGIMEN WITH A HIGH REMISSION RATE

EHA Library, Daniel J. DeAngelo, 181490

TARGETED SINGLE CELL SEQUENCING TO IDENTIFY MUTATIONAL HIERARCHY IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Jolien De Bie, 181438

CM942 IS A NEW SMALL MOLECULE THAT TARGETS SET-PP2A INTERACTION AND INHIBITS GROWTH OF ACUTE MYELOID LEUKEMIA CELLS

EHA Library, Patricia García Ramírez, 181492

CLONAL HETEROGENEITY IN LEUKEMIC STEM CELLS FROM PATIENTS WITH ACUTE MYELOID LEUKEMIA

EHA Library, Linda Manta, 181493

TREATMENT OF PRACINOSTAT AND AZACITIDINE IN ELDERLY PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML): CORRELATION BETWEEN MUTATION CLEARANCE AND CLINICAL RESPONSE

EHA Library, Elena Palmesino, 181494

STABLE DISEASE WITH HEMATOLOGIC IMPROVEMENT IS CLINICALLY MEANINGFUL FOR OLDER PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) TREATED WITH AZACITIDINE

EHA Library, Andre C. Schuh, 181495

A RANDOMIZED PHASE II STUDY OF IDARUBICIN AND CYTARABINE WITH EITHER CLOFARABINE (CIA) OR FLUDARABINE (FIA) IN ADULTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA

EHA Library, Nicholas Short, 181496

OVERALL SURVIVAL AND TRANSPLANTATION IN PATIENTS WITH FLT3 MUTATIONS: SUBGROUP ANALYSIS OF A PHASE 3 STUDY OF CPX-351 VERSUS 7+3 IN OLDER ADULTS WITH NEWLY DIAGNOSED, HIGH-RISK ACUTE MYELOID LEUKEMIA

EHA Library, Bruno Medeiros, 181497

NIVOLUMAB MAINTENANCE THERAPY FOR PATIENTS WITH HIGH-RISK ACUTE MYELOID LEUKEMIA (AML) IN REMISSION

EHA Library, Tapan Kadia, 181498

HIGHER EXPRESSION OF LONG NON-CODING RNA KIAA0125 IS ASSOCIATED WITH CHARACTERISTIC CLINICAL AND BIOLOGICAL FEATURES AND IS AN INDEPENDENT POOR PROGNOSTIC FACTOR IN ACUTE MYELOID LEUKEMIA

EHA Library, Sheng-Yu Hung, 181499

LEUKEMIC STEM CELLS CAN BE DETECTED IN A CONSIDERABLE PERCENTAGE OF PATIENTS WITH ACUTE MYELOID LEUKEMIA AT DIAGNOSIS AND IS A SIGNIFICANT PROGNOSTIC FACTOR

EHA Library, Olga Perez-Lopez, 181500

POST-REMISSIONAL AND PRE-TRANSPLANT ROLE OF MINIMAL RESIDUAL DISEASE DETECTED BY WT1 IN ACUTE MYELOID LEUKEMIA: A RETROSPECTIVE COHORT STUDY

EHA Library, Chiara Frairia, 181501

DIFFERENTIATION SYNDROME ASSOCIATED WITH ENASIDENIB (AG-221), A SELECTIVE INHIBITOR OF MUTANT ISOCITRATE DEHYDROGENASE 2 (MIDH2)

EHA Library, Amir T. Fathi, 181502

OUTCOME OF PATIENTS WITH INTRAVASCULAR B-CELL LYMPHOMA, A RETROSPECTIVE STUDY CONDUCTED ON BEHALF OF THE LYMPHOMA STUDY ASSOCIATION (LYSA) GROUP

EHA Library, Antoine BONNET, 181504

OUTCOME OF ELDERLY DLBCL PATIENTS (≥ 80 YEARS) TREATED WITH ANTHRACYCLINE BASED CHEMOTHERAPY; R-CHOP DOSE REDUCTION IS NOT NECESSARY FOR EVERYBODY

EHA Library, Marek Trneny, 181505

IMPROVED SURVIVAL IN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL) UP TO AGE 70 ONLY: A POPULATION-BASED STUDY ON INCIDENCE, PRIMARY TREATMENT AND SURVIVAL IN THE NETHERLANDS, 1989-2015

EHA Library, Avinash Dinmohamed, 181506

CLINICAL CHARACTERISTICS AND LONG-TERM RESULTS OF TREATMENT OF DIFFUSE LARGE HEPATITIS C - ASSOCIATED NON-HODGKIN LYMPHOMA (DLBCL + C).

EHA Library, sergey lepkov, 181507

Cardiac MR and 82 Rubidium PET for early detection of doxorubicin-induced cardiotoxicity in patients with malignant lymphoma

EHA Library, Adam Høgsbro Laursen, 181508

RELAPSE CHARACTERISTICS AND THE ROLE OF SURVEILLANCE COMPUTED TOMOGRAPHY IN AGGRESSIVE NON-HODGKIN LYMPHOMA

EHA Library, Ka-Won Kang, 181510

A MULTI-CENTER STUDY OF GLIDE CHEMOTHERAPY CONSOLIDATED WITH AUTOLOGOUS STEM CELL TRANSPLANTATION FOR NEWLY DIAGNOSED STAGE IV AND RELAPSED EXTRANODAL NATURAL KILLER/T-CELL LYMPHOMA PATIENTS

EHA Library, Jie Ji, 181511

LONG TERM FOLLOW-UP OF PATIENTS WITH PERIPHERAL T-CELL LYMPHOMAS TREATED WITH IFOSFAMIDE, ETOPOSIDE, EPIRUBICIN / INTERMEDIATE METHOTREXATE AND AUTOLOGOUS STEM CELL TRANSPLANTATION

EHA Library, Michal Sieniawski, 181512

STROMA-DERIVED FACTORS STIMULATE JAK/STAT SIGNALING IN AML CELLS RESULTING IN RESISTANCE TO BCL2 INHIBITOR VENETOCLAX

EHA Library, Riikka Karjalainen, 181468

THE ESSENTIAL ROLE OF THE ENHANCERS OF POLYCOMB EPC1 AND EPC2 IN MLL-AF9 ACUTE MYELOID LEUKAEMIA IS A ‘COMPLEX' STORY

EHA Library, Niamh Mannion, 181467

ACUTE MYELOID LEUKEMIA EVOLUTION CAN BE RECONSTRUCTED BY ANALYSIS OF NON-LEUKEMIC CELLULAR SUBCOMPARTMENTS AND MULTI-LINEAGE ENGRAFTED MICE

EHA Library, Borhan Saeed, 181466

DECIPHERING THE ONCOGENIC NETWORK OF PRC2 LOSS GUIDED LEUKEMOGENISIS

EHA Library, Jan-Henning Klusman, 181464

THE PMLC62A/C65A KNOCK-IN MOUSE MODEL PROVIDES EVIDENCE FOR THE ROLE OF NUCLEAR BODY DISRUPTION IN THE PATHOGENESIS OF ACUTE PROMYELOCYTIC LEUKEMIA

EHA Library, Edwige Voisset, 181463

A DUAL BH3-MIMETIC APPROACH TARGETING BOTH BCL-2 AND MCL1 IS HIGHLY EFFICACIOUS AND WELL-TOLERATED IN ACUTE MYELOID LEUKEMIA

EHA Library, Donia Moujalled, 181462

THE LONG NON-CODING RNA HOXB-AS3 REGULATES RIBOSOMAL BIOGENESIS IN NPM1-MUTATED ACUTE MYELOID LEUKEMIA

EHA Library, Dimitrios PAPAIOANNOU, 181461

NUCLEAR RE-LOCALIZATION OF NPM1C+ INDUCES DIFFERENTIATION AND CELL GROWTH ARREST

EHA Library, Lorenzo Brunetti, 181460

BRANCHED CHAIN AMINO ACID METABOLISM REGULATES ALPHA-KETOGLUTARATE HOMEOSTASIS RESEMBLING MUTANT-IDH DRIVEN DNA HYPERMETHYLATION IN AML

EHA Library, Simon Raffel, 181459

RECURRENT MYB REARRANGEMENT IN BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM

EHA Library, KYOGO SUZUKI, 181458

INOTUZUMAB OZOGAMICIN IN COMBINATION WITH LOW-INTENSITY CHEMOTHERAPY (MINI-HYPER-CVD) AS FRONTLINE THERAPY FOR OLDER PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA: UPDATED RESULTS FROM A PHASE I/II TRIAL

EHA Library, Nicholas Short, 181457

MINIMAL DISSEMINATED DISEASE DETECTION BY FLOWCYTOMETRIC IMMUNOPHENOTYPING IN T-CELL ACUTE LYMPHOBLASTIC LYMPHOMA

EHA Library, Ganesh Kumar Viswanathan, 181456

PEDIATRIC MLL ACUTE LEUKEMIA PATIENTS SHOW DIFFERENTIAL HDAC EXPRESSION

EHA Library, Nerea Vega-Garcia, 181455

THE TETRASPANIN CD9 IS A PROGNOSTIC MARKER FOR PREDICTING SURVIVAL OUTCOMES OF PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Kam Tong Leung, 181454

MANAGEMENT AND OUTCOME OF ADULT PH+ ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) PATIENTS TREATED AT THE “SAPIENZA” UNIVERSITY BETWEEN 1996 AND 2016

EHA Library, Sabina Chiaretti, 181453

CLINICAL OUTCOMES OF ELDERLY ACUTE LYMPHOBLASTIC LEUKEMIA/LYMPHOMA - A SINGLE INSTITUTION EXPERIENCE

EHA Library, Kevin Miller, 181452

RESULTS FROM UKALL60+, A UK/HOVON COLLABORATIVE PHASE 2 STUDY IN ELDERLY PATIENTS WITH UNTREATED ACUTE LYMPHOBLASTIC LEUKAEMIA

EHA Library, Nick MORLEY, 181451

CLINICAL SIGNIFICANCE OF END OF INDUCTION MINIMAL RESIDUAL DISEASE IN ADULT PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) IN COMPLETE REMISSION AFTER A SINGLE CHEMOTHERAPY COURSE

EHA Library, Renato Bassan, 181450

PRO-T CELL ALL/LBL: AN ULTRA-HIGH RISK CD2-NEGATIVE DISEASE SUBTYPE IN ADULTS DEFINED BY FLOW CYTOMETRY

EHA Library, Beata Ostrowska, 181449

PROGNOSTIC SIGNIFICANCE OF MINIMAL RESIDUAL DISEASE DETECTED BY MLL FUSION GENE TRANSCRIPTS IN INFANT ACUTE LYMPHOBLASTIC LEUKEMIA. UPDATED RESULTS OF 76 PATIENTS ENROLLED INTO MLL-BABY STUDY

EHA Library, Grigory Tsaur, 181448

IKZF1Δ4-7 CAN BE EASILY SCREENED BY PCR BUT DOES NOT PREDICT OUTCOME IN ADULTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA; DATA FROM 490 PATIENTS ENROLLED ON THE UKALL14 TRIAL.

EHA Library, Rachel Mitchell, 181447

PHARMACOLOGICAL ACTIVITY OF CB-103 - AN ORAL PAN-NOTCH INHIBITOR WITH A NOVEL MODE OF ACTION

EHA Library, Dirk Weber, 181446

PRECLINICAL ACTIVITY OF ENTOSPLETINIB IN CHILDHOOD B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Sarah Tasian, 181445

IL-7 FLEXIBLY REGULATES AUTOPHAGY-DEPENDENT VIABILITY OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA CELLS

EHA Library, Daniel Ribeiro, 181444

GENETIC ACTIVATION AND THERAPEUTIC TARGETING OF PIM1 IN T-CELL ACUTE LYMPHOBLASTIC LYMPHOMA

EHA Library, Renate De Smedt, 181443

TP53 MUTATIONS DISRUPTING DNA BINDING LEAD TO CHEMOTHERAPY RESISTANCE IN ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Malwine Pogodzinski, 181442

REPOSITIONING EXISTING DRUGS AS NOVEL THERAPEUTICS: OXIDATIVE STRESS AS A TARGET FOR HIGH-RISK LEUKAEMIA IN CHILDREN

EHA Library, Mawar Karsa, 181441

TRANSLATOME ANALYSIS OF THE T-ALL ASSOCIATED RIBOSOMAL PROTEIN L10 R98S MUTATION REVEALS ALTERED SERINE METABOLISM

EHA Library, Laura Fancello, 181440

BCL-2 INHIBITION AS NEW THERAPEUTIC OPPORTUNITY FOR RPL10 R98S MUTANT PEDIATRIC T-ALL

EHA Library, Kim Kampen, 181439

A PHASE 2 STUDY OF GLASDEGIB (PF-04449913) IN COMBINATION WITH CYTARABINE AND DAUNORUBICIN IN UNTREATED PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) OR HIGH-RISK MYELODYSPLASTIC SYNDROME (MDS)

EHA Library, Jorge Cortes, 181491