PHASE III RANDOMIZED TRIAL OF VOLASERTIB PLUS LOW-DOSE CYTARABINE (LDAC) VERSUS PLACEBO PLUS LDAC IN PATIENTS AGED ?65 YEARS WITH PREVIOUSLY UNTREATED AML, INELIGIBLE FOR INTENSIVE THERAPY

EHA Library, Hartmut Döhner, 135257

HIGH THROUGHPUT SEQUENCING AS A MEASURE OF EARLY RESPONSE TO THERAPY IN CHILDHOOD ALL

EHA Library, Ilan Kirsch, 135252

GENETIC VARIATION AT HBS1L-MYB AND GFI1B-GTF3C5 INFLUENCES WHETHER JAK2 V617F MUTATED MPN PRESENT WITH ET OR PV

EHA Library, Nick Cross, 135262

TUMOR-SPECIFIC GLYCOSYLATED CD43 IS A NOVEL AND HIGHLY SPECIFIC TARGET FOR ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROME

EHA Library, Mette Hazenberg, 135267

DISREGULATED MEGAKARYOCYTE MIGRATION AND MATURATION IS POSSIBLY DUE TO IMPAIRED BONE MARROW SYMPATHETIC NERVETHROUGH NESTIN+ MESENCHYMAL STEM CELL IN CHRONIC IMMUNE THROMBOCYTOPENIA

EHA Library, Yan Su, 135272

PD-1 GENOTYPE OF THE DONOR AND ACUTE GRAFT-VERSUS-HOST DISEASE AFTER HLA-IDENTICAL SIBLING DONOR STEM CELL TRANSPLANTATION

EHA Library, Nazly Santos, 135277

Targeted genome editing in hematopoietic stem cells

EHA Library, Luigi Naldini, 137089

Immune checkpoint blockade in lymphoma

EHA Library, Philippe Armand, 137088

Jean Bernard Lifetime Achievement Award: Acceptance Speech - Iron, erythropoiesis and beyond

EHA Library, Clara Camaschella, 137085

EFFECTS OF AG-348, A PYRUVATE KINASE ACTIVATOR, ON ANEMIA AND HEMOLYSIS IN PATIENTS WITH PYRUVATE KINASE DEFICIENCY: EARLY DATA FROM THE DRIVE PK STUDY

EHA Library, Rachael F Grace, 135222

THREE CASES OF CYCLIC NEUTROPENIA WITH ACQUIRED CSF3R MUTATIONS, ONE DEVELOPING AML

EHA Library, Cornelia Zeidler, 135232

LOSS OF FUNCTION SETD2 MUTATIONS LEAD TO RESISTANCE TO DNA DAMAGING CHEMOTHERAPY IN LEUKEMIA

EHA Library, Josephine Kahn, 135217

ACTIVATION OF THE THROMBOPOIETIN RECEPTOR BY MUTANT CALRETICULIN IN CALR-MUTANT MYELOPROLIFERATIVE NEOPLASMS

EHA Library, Marito Araki, 135212

THERAPEUTIC IMPACT OF TAK-1 INHIBITION ON TUMOR GROWTH AND BONE DESTRUCTION IN MYELOMA

EHA Library, Masahiro Okabe, 135207

CLONAL ORIGIN OF THERAPY-RELATED MYELOID NEOPLASMS

EHA Library, Koichi Takahashi, 135202

ACALABRUTINIB, A SECOND-GENERATION BRUTON TYROSINE KINASE (BTK) INHIBITOR, IN PREVIOUSLY UNTREATED CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

EHA Library, William Wierda, 135187

THALIDOMIDE FOR HEREDITARY HEMORRHAGIC TELANGIECTASIA: EFFICACY AND SAFETY OF LONG-TERM TREATMENT

EHA Library, Rosangela Invernizzi, 135227

ANALYSIS OF SECONDARY NEOPLASIAS AFTER HIGH DOSE THERAPY SUPPORTED BY AUTOLOGOUS STEM CELL TRANSPLANTATION IN FOLICULAR LYMPHOMA PATIENTS. A LONG TERM FOLLOW-UP ANALYSIS FROM THE GELTAMO REGISTRY.

EHA Library, Ana Jiménez Ubieto, 135197

ALLELES OF SNPS IN REGULATORY REGIONS OF SLC22A4 AND SLC22A5 GENES ARE SIGNIFICANTLY ASSOCIATED WITH STABLE MAJOR MOLECULAR RESPONSE TO IMATINIB FIRST LINE IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA

EHA Library, Katerina Machova Polakova, 135192

HIGH GENE EXPRESSION OF HIST1H2AG AND HIST1H4A REDUCES IMATINIB UPTAKE INTO CML CELLS AND PREDICTS POOR RESPONSE TO FRONTLINE IMATINIB THERAPY

EHA Library, Chung Hoow Kok, 135191

OBINUTUZUMAB PLUS BENDAMUSTINE VERSUS BENDAMUSTINE ALONE IN PATIENTS WITH RITUXIMAB-REFRACTORY FOLLICULAR LYMPHOMA: RESULTS FROM THE GADOLIN STUDY

EHA Library, Marek Trneny, 135196

SF3B1 MUTATIONS IN MDS-RS ARISE IN MULTIPOTENT HEMOPOETIC STEM CELLS

EHA Library, Teresa Mortera-Blanco, 135201

IBRUTINIB PLUS BENDAMUSTINE AND RITUXIMAB IN PREVIOUSLY TREATED CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA (CLL/SLL): 2-YEAR FOLLOW-UP INCLUDING MRD FROM THE HELIOS STUDY

EHA Library, Graeme Fraser, 135186

FIRST PROSPECTIVE RESULTS OF JOINT DISTRACTION IN SEVERE HEMOPHILIC ANKLE ARTHROPATHY

EHA Library, Lize F. D. van Vulpen, 135226

PD-1 BLOCKADE ENHANCES THE EFFICACY OF ELOTUZUMAB IN MOUSE TUMOR MODELS

EHA Library, Natalie Bezman, 135206

HSC GENETIC HETEROGENEITY DETERMINES CLONAL DYNAMICS IN PMF

EHA Library, Ioanna Triviai, 135211

A NOVEL EPIGENETIC RESISTANCE MECHANISM TO THE FLT3 INHIBITOR PKC412 INDUCES CROSS-RESISTANCE TO STANDARD CHEMOTHERAPY IN ACUTE MYELOID LEUKEMIA (AML)

EHA Library, Stefanie Göllner, 135216

NEXT GENERATION TARGETED SEQUENCING IMPROVED THE PRECISE DIAGNOSIS OF PEDIATRIC APLASTIC ANEMIA /INHERITED BONE MARROW FAILURE SYNDROMES

EHA Library, Wenbin An, 135231

A PHASE I/II STUDY OF AUTOLOGOUS HEMATOPOIETIC STEM CELLS GENETICALLY MODIFIED WITH GLOBE LENTIVIRAL VECTOR FOR THE TREATMENT OF TRANSFUSION DEPENDENT BETA-THALASSEMIA

EHA Library, Sarah Marktel, 135221

THE EUTOS LONG-TERM SURVIVAL SCORE IS PREDICTIVE FOR RESPONSE AND OUTCOME IN CML PATIENTS TREATED FRONTLINE WITH NILOTINIB-BASED REGIMENS

EHA Library, Fausto Castagnetti, 135190

SEQUENCE VARIANTS IN PATIENTS WITH PRIMARY AND ACQUIRED RESISTANCE TO IBRUTINIB IN THE PHASE 3 MCL3001 (RAY) TRIAL

EHA Library, Georg Lenz, 135195

A SUBCUTANEOUSLY ADMINISTERED INVESTIGATIONAL RNAI THERAPEUTIC (ALN-CC5) TARGETING COMPLEMENT C5 FOR TREATMENT OF PNH AND COMPLEMENT-MEDIATED DISEASES: INTERIM PHASE 1 STUDY RESULTS

EHA Library, Anita Hill, 135230

HEDGEHOG SIGNALING PATHWAY INHIBITOR, PF-04449913 LIMITS THE SELF-RENEWAL OF MDS-DERIVED INDUCED POTENT STEM CELLS (IPSC): MOLECULAR MECHANISMS

EHA Library, Tetsuzo Tauchi, 135200

DEFINING NEW THERAPEUTIC AGENTS THAT TARGET THE ONCOGENIC TRANSLATION PROGRAM IN MULTIPLE MYELOMA

EHA Library, Salomon Manier, 135205

EVALUATION OF 243 PATIENTS WITH DELETION 17P CHRONIC LYMPHOCYTIC LEUKEMIA TREATED WITH IBRUTINIB: A CROSS-STUDY ANALYSIS OF TREATMENT OUTCOMES

EHA Library, Jeffrey Jones, 135185

A FUSION PROTEIN OF INTERLEUKIN-4 AND INTERLEUKIN-10 PROTECTS AGAINST BLOOD-INDUCED CARTILAGE DAMAGE IN VITRO AND IN VIVO

EHA Library, Lize F. D. van Vulpen, 135225

RUXOLITINIB (RUX) REDUCES JAK2V617F ALLELE BURDEN (AB) IN PATIENTS (PTS) WITH POLYCYTHEMIA VERA (PV) ENROLLED IN THE RESPONSE STUDY

EHA Library, Alessandro M. Vannucchi, 135210

THE RET RECEPTOR TYROSINE KINASE PROMOTES ACUTE MYELOID LEUKEMIA THROUGH PROTECTION OF FLT3-ITD MUTANTS FROM AUTOPHAGIC DEGRADATION

EHA Library, Saskia Rudat, 135215

CHILDREN WITH SICKLE CELL ANEMIA ON CHRONIC TRANSFUSION FOR ABNORMAL TRANSCRANIAL DOPPLER VELOCITIES. PATIENT/SIBLING COMPARISON OF COGNITIVE PERFORMANCES AND ASSOCIATION WITH NEUROIMAGING DATA

EHA Library, Francoise Bernaudin, 135220

BONE MARROW FAILURE IN PAROXYSMAL NOCTURNAL HEMOGLOBULINURIA IS ASSOCIATED WITH EXPANSION OF ANTIGEN-SELECTED T CELLS: HIGH-THROUGHPUT EVIDENCE

EHA Library, Evangelia Stalika, 135229

OVERALL SURVIVAL OUTCOMES IN PATIENTS WITH MANTLE-CELL LYMPHOMA (MCL) TREATED WITH IBRUTINIB IN A POOLED ANALYSIS OF 370 PATIENTS FROM 3 INTERNATIONAL OPEN-LABEL STUDIES

EHA Library, Simon Rule, 135194

GLUCOSE AND LIPID METABOLISM ABNORMALITIES DURING NILOTINIB TREATMENT AND COMPARISON WITH IMATINIB AND DASATINIB THERAPY ? RESULTS FROM ENIGMA 2 STUDY

EHA Library, Zdenek Racil, 135189

INTEGRATIVE GENOMICS IDENTIFIES THE MOLECULAR BASIS OF RESISTANCE TO AZACITIDINE THERAPY IN MYELODYSPLASTIC SYNDROMES

EHA Library, Ashwin Unnikrishnan, 135199

A NEW MULTIPLE MYELOMA CLASSIFICATION SYSTEM THAT CORRELATES TO DISEASE STAGE AND PROGNOSIS - INDICATION OF REVERSIBLE PHENOTYPIC PLASTICITY AS A HALLMARK

EHA Library, Hans Erik Johnsen, 135204

IMPACT OF THE MOLECULAR PROFILE ON THE RISK OF ACUTE MYELOID TRANSFORMATION IN PATIENTS WITH POLYCYTHEMIA VERA AND ESSENTIAL THROMBOCYTHEMIA

EHA Library, Alberto Alvarez-Larrán, 135209

QUANTITATIVE MRD IS PROGNOSTIC FOR PROGRESSION-FREE & OVERALL SURVIVAL IN ELDERLY PATIENTS RECEIVING CHLORAMBUCIL ALONE OR WITH OBINUTUZUMAB/RITUXIMAB: A PROSPECTIVE ANALYSIS OF THE GCLLSG CLL11 STUDY

EHA Library, Matthias Ritgen, 135184

RESPONSIVENESS OF HEMOPHILIA B-CAUSING NONSENSE MUTATIONS TO RIBOSOME READTHROUGH-INDUCING DRUGS STRICTLY DEPENDS ON THE NUCLEOTIDE AND PROTEIN CONTEXT

EHA Library, Alessio Branchini, 135224

FLT3-D835Y AND NPM1C ONCOGENES COOPERATE TO INDUCE AN AGGRESSIVE MPN IN MICE.

EHA Library, Alina Rudorf, 135214

DOPPLER ULTRASOUND RELIABLY IDENTIFIES SICKLE CELL DISEASE ADULT PATIENTS WITH INTRACRANIAL VASCULOPATHY

EHA Library, Pablo Bartolucci, 135219

RESULTS OF TRANSCRANIAL DOPPLER ULTRASOUND SCREENING FROM THE POST-STOP STUDY

EHA Library, Julie Kanter, 135218

FIRST RESULTS FROM A DOSE-ESCALATING STUDY WITH AAV5 VECTOR CONTAINING WILD TYPE HUMAN FACTOR IX GENE THERAPY IN PATIENTS WITH SEVERE OR MODERATELY-SEVERE HAEMOPHILIA B

EHA Library, Frank Leebeek, 135223

NPM1 AND FLT3-ITD MUTATIONS SINERGISTICALLY INDUCE GATA1 EPIGENETIC SILENCING IN A AML MOUSE MODEL

EHA Library, Paolo Sportoletti, 135213

A TARGETED SEQUENCING APPROACH IN MULTIPLE MYELOMA REVEALS A COMPLEX LANDSCAPE OF GENOMIC LESIONS THAT HAS IMPLICATIONS FOR PROGNOSIS

EHA Library, Niccolò Bolli, 135203

DYNAMICS OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES.

EHA Library, Hideki Makishima, 135198

DYSREGULATED MIR34A/DIACYLGLYCEROL KINASE ? INTERACTION ENHANCES T-CELL ACTIVATION IN ACQUIRED APLASTIC ANEMIA

EHA Library, Yuanxin Sun, 135228

15-YEAR FOLLOW-UP OF THE NORDIC MCL2-TRIAL: DESPITE LONG-TERM RESPONSES LATE RELAPSES STILL OCCUR.

EHA Library, Christian Winther Eskelund, 135193

EFFICACY AND SAFETY OF IMATINIB GENERICS; A REPORT FROM POLISH (PALG) IMATINIB GENERICS REGISTRY

EHA Library, Tomasz Sacha, 135188

PRELIMINARY SAFETY DATA FROM THE PHASE 3B GREEN STUDY OF OBINUTUZUMAB (G) ALONE OR COMBINED WITH CHEMOTHERAPY FOR PREVIOUSLY UNTREATED OR RELAPSED/REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

EHA Library, Véronique Leblond, 135183

LONG-TERM OUTCOMES OF RUXOLITINIB (RUX) THERAPY IN PATIENTS (PTS) WITH MYELOFIBROSIS (MF): 5-YEAR FINAL EFFICACY AND SAFETY ANALYSIS FROM COMFORT-I

EHA Library, Srdan Verstovsek, 135208

Patents and diagnostic testing: another marriage on the rocks or a(n) (un)wanted relationship?

EHA Library, Sven Bostyn, 137078

Clones and subclones during ALL development

EHA Library, Jan Trka, 137083

Patenting in diagnostics: Damned if you do, damned if you don't

EHA Library, Eric Claassen, 137077

Oncogenetic heterogeneity of ALL cells

EHA Library, Stephen P. Hunger, 137082

Q&A and Panel Discussion

EHA Library, Faculty / Presenters, 141696

The meaning of circulating plasma cells in myeloma patients

EHA Library, Bruno Paiva, 137072

Symptoms and health-related quality of life issues considered important by patients with hematological malignancies: Patient perspective

EHA Library, Roger Else, 137067

Multiple myeloma: Spatial genomic heterogeneity between focal lesions and random bone marrow

EHA Library, Niels Weinhold, 137071

Challenges of assessing symptom burden in patients with hematological malignancies: Academic perspective

EHA Library, Tatyana Ionova, 137066

Hemostatic management of bleeding in obstetrics and gynecology

EHA Library, Claire Philipp, 136658

Genetic basis of rare inherited platelet disorders in the era of next-generation sequencing

EHA Library, Kathleen Freson, 136657

Blood outgrowth endothelial cells in understanding von Willebrand disease

EHA Library, Anna M Randi, 136656

B-cell maturation pathways and migration

EHA Library, Alberto Orfao, 137070

Challenges of assessing symptoms for monitoring response to treatment in patients with ematological malignancies: Learning from best practice

EHA Library, Jonathan Kell, 137065

International Harmonization Group For Surveillance Of Late Effects Of Childhood Cancer

EHA Library, Leontien Kremer, 136655

The spectrum of late effects after cancer, lessons from pediatric oncology, and the value of international collaboration

EHA Library, Roderick Skinner, 136654

Deciphering genetic variation of early and late effects from childhood cancer therapies

EHA Library, Bruce Carleton, 136653

Antiplatelet therapy in acute and chronic ischemic heart disease

EHA Library, Freek Verheugt, 136652

Platelet reactivity testing: Is there a clinical relevance?

EHA Library, Jolanta Siller-Matula, 136651

Platelets and immunity

EHA Library, Harald Langer, 136650

Treatment of HLH in adults

EHA Library, Nancy Berliner, 136649

Malignancy associated HLH

EHA Library, Milen Minkov, 136648

HLH: Variations in etiology, pathophysiology and manifestations

EHA Library, Michael Jordan, 136647

The role of the blood film in diagnosing and managing red cell disorders

EHA Library, Barbara Bain, 136646

Clinical trials and potential targets of therapy in sickle cell disease

EHA Library, Bart Biemond, 136645

Anemia of chronic disease - New insights into its pathophysiology and therapy

EHA Library, Guenter Weiss, 136644

Mesenchymal Stem Cells As Treatment Of Chronic GvHD

EHA Library, Katarina Le Blanc, 136676

GVHD prophylaxis with PTCy

EHA Library, leo leonio, 136675

Recent advances in understanding the pathophysiology of GVHD

EHA Library, Ron Chakraverty, 136674

ADULTS AND CHILDREN (1-45 YEARS) WITH PH-NEGATIVE ALL HAVE ALMOST IDENTICAL OUTCOME IN RISK-STRATIFIED ANALYSIS OF NOPHO ALL2008

EHA Library, Nina Toft, 135343

DEVELOPMENT OF A NOVEL FIRST-IN-CLASS ORAL INHIBITOR OF THE NOTCH PATHWAY.

EHA Library, Rajwinder Lehal, 133148

FUNCTIONAL RESTORATION OF MUTANT P53 AND CELL DEATH SENSITIZATION IN ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Salih demir, 133146

DETERMINING THE MUTATIONAL LANDSCAPE OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA REVEALS NR3C1 DELETIONS AND ACTIVATING MUTATIONS IN IL7R SIGNALING AS CAUSE OF STEROID RESISTANCE

EHA Library, Jules Meijerink, 133147

CHARACTERIZATION OF AN EX VIVO T-CELL CULTURE MODEL FOR THE STUDY OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Simon Bornschein, 133145

CLINICAL AND BIOLOGICAL LANDSCAPE OF DRIVER MUTATIONS IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Hiroo Ueno, 133144

THE NUP214-ABL1 FUSION COOPERATES WITH TLX1 IN THE DEVELOPMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Marlies Vanden Bempt, 133143

A PLATFORM FOR DETECTION OF FUSION GENES IN ALL FROM TARGET CAPTURE NEXT-GENERATION SEQUENCING OF DNA AND RNA.

EHA Library, Andrea Grioni, 133142

IDENTIFICATION OF CANDIDATE ONCOGENES AND CHROMOSOMAL BREAKPOINT SEQUENCING BY TARGETED LOCUS AMPLIFICATION IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Pieter Van Vlierberghe, 133141

HEDGEHOG PATHWAY ACTIVATION IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA PREDICTS RESPONSE TO SMO AND GLI1 INHIBITORS

EHA Library, Jolien De Bie, 133140

MEF2C DYSREGULATION IS ASSOCIATED WITH CDKN1B DELETIONS AND PREDICTS POOR GLUCOCORTICOID RESPONSE IN PEDIATRIC T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

EHA Library, Sara Colomer-Lahiguera, 133139

COMPARATIVE ANALYSIS OF GENE REGULATORY NETWORKS IN LYMPHOID LEUKEMIAS USING THE INTERACTIVE HEMAP RESOURCE

EHA Library, Juha Mehtonen, 133138