Contributions
Abstract: PB1773
Type: Publication Only
Session title: Sickle cell disease
Background
Sickle cell anemia (SCA) is a chronic problem with growing with ages consequences. It starts with birth & continues to add complication throughout the patient’s life. During his childhood the patient develop a psychological bond with his treating team which makes it traumatic to him when he is transferred to adult hematology service which might lead to loss of interest in receiving treatment and skipping follow up visits which eventually leads to increased complications and either stopping treatment or developing treatment related adverse events.
Aims
This is a descriptive study regarding Adult (above the age of 18) SCA patients on follow up with the clinical hematology unit Oncology center Mansoura University, Dakahlia, Egypt who had recorded follow up visits on our System in the period between 2005 and 2020 regarding their age at diagnosis, sex, baseline criteria, presence of crisis or not method of diagnosis and their follow up regimen. To outline the Demographic characters of Egyptian SCA patients on regular follow up at an adult academic hematology center in Egypt and the characters of their disease
This is a descriptive study regarding Adult (above the age of 18) SCA patients on follow up with the clinical hematology unit Oncology center Mansoura University, Dakahlia, Egypt who had recorded follow up visits on our System in the period between 2005 and 2021 regarding their age at diagnosis, sex, baseline criteria, presence of crisis or not method of diagnosis and their follow up regimen.
By reviewing the data on our system over the period of 1-1-2005 and 1-1-2020 we found that we have 39 SCD anemia patients with 19 males (48.7%) and 20 females (51.3%) as shown in figure 1, Four patients had a less than six months follow up so they were excluded from the final analysis.By reviewing the data on our system over the period of 1-1-2005and 1-1-2020 we found that we have 39 SCD anemia patients with 19 males(48.7%) and 20 females (51.3%) as shown in figure 1, Four patients had aless than six months follow up so they were excluded from the final analysis.
Results
By reviewing the data on our system over the period of 1-1-2005 and 1-1-2021 we found that we have 39 SCD anemia patients with 19 males (48.7%) and 20 females (51.3%) , The average age at referral to our center was 24 years with the range of 14.6 – 37.4 years, The median follow up of our patients was 114.8 months (357 – 6).Out of our 35 patients twenty five (71.4 %) were referred to us from the pediatric service while the remaining ten (28.6 %) were newly diagnosed at our unit. Using Hemoglobin electrophoresis twenty eight patients (71.8 %) had done this investigation which showed that 11 (39 %) had sickle-thalassemia while the rest were pure SCA. Spleen was surgically removed in 7 (17.9 %), Non-visualized in 8 (20.6 %) while the remaining 22 had spleen measurable by ultrasonography. 12 (30.7 %) patients had HCV infection, Twenty four (61.5 %) were non transfusion dependent while the remaining 11 (28.2 %) required monthly transfusion. As regard all our 39 patients were accounted for at the time of data analysis
Conclusion
Children with SCA need a more smooth transfer fromtheir pediatric service to adult service to help them to be more adherent to follow up instead of showing up when they have a problem, require transfusion or in need of a grave intervention and on the other hand all SCA patients require more thorough chelation therapy and supportive measures to avoid end organ damage.
Keyword(s):
Abstract: PB1773
Type: Publication Only
Session title: Sickle cell disease
Background
Sickle cell anemia (SCA) is a chronic problem with growing with ages consequences. It starts with birth & continues to add complication throughout the patient’s life. During his childhood the patient develop a psychological bond with his treating team which makes it traumatic to him when he is transferred to adult hematology service which might lead to loss of interest in receiving treatment and skipping follow up visits which eventually leads to increased complications and either stopping treatment or developing treatment related adverse events.
Aims
This is a descriptive study regarding Adult (above the age of 18) SCA patients on follow up with the clinical hematology unit Oncology center Mansoura University, Dakahlia, Egypt who had recorded follow up visits on our System in the period between 2005 and 2020 regarding their age at diagnosis, sex, baseline criteria, presence of crisis or not method of diagnosis and their follow up regimen. To outline the Demographic characters of Egyptian SCA patients on regular follow up at an adult academic hematology center in Egypt and the characters of their disease
This is a descriptive study regarding Adult (above the age of 18) SCA patients on follow up with the clinical hematology unit Oncology center Mansoura University, Dakahlia, Egypt who had recorded follow up visits on our System in the period between 2005 and 2021 regarding their age at diagnosis, sex, baseline criteria, presence of crisis or not method of diagnosis and their follow up regimen.
By reviewing the data on our system over the period of 1-1-2005 and 1-1-2020 we found that we have 39 SCD anemia patients with 19 males (48.7%) and 20 females (51.3%) as shown in figure 1, Four patients had a less than six months follow up so they were excluded from the final analysis.By reviewing the data on our system over the period of 1-1-2005and 1-1-2020 we found that we have 39 SCD anemia patients with 19 males(48.7%) and 20 females (51.3%) as shown in figure 1, Four patients had aless than six months follow up so they were excluded from the final analysis.
Results
By reviewing the data on our system over the period of 1-1-2005 and 1-1-2021 we found that we have 39 SCD anemia patients with 19 males (48.7%) and 20 females (51.3%) , The average age at referral to our center was 24 years with the range of 14.6 – 37.4 years, The median follow up of our patients was 114.8 months (357 – 6).Out of our 35 patients twenty five (71.4 %) were referred to us from the pediatric service while the remaining ten (28.6 %) were newly diagnosed at our unit. Using Hemoglobin electrophoresis twenty eight patients (71.8 %) had done this investigation which showed that 11 (39 %) had sickle-thalassemia while the rest were pure SCA. Spleen was surgically removed in 7 (17.9 %), Non-visualized in 8 (20.6 %) while the remaining 22 had spleen measurable by ultrasonography. 12 (30.7 %) patients had HCV infection, Twenty four (61.5 %) were non transfusion dependent while the remaining 11 (28.2 %) required monthly transfusion. As regard all our 39 patients were accounted for at the time of data analysis
Conclusion
Children with SCA need a more smooth transfer fromtheir pediatric service to adult service to help them to be more adherent to follow up instead of showing up when they have a problem, require transfusion or in need of a grave intervention and on the other hand all SCA patients require more thorough chelation therapy and supportive measures to avoid end organ damage.
Keyword(s):