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THE IMPACT OF COVID-19 ON PATIENTS WITH HEMATOLOGICAL MALIGNANCIES: THE MIXED-METHOD ANALYSIS OF AN ISRAELI NATIONAL SURVEY
Author(s): ,
Ilana Levy
Affiliations:
Hematology,Bnai Zion Medical Center,Haifa,Israel;Faculty of Medicine,Technion- Israel Institute of Technology,Haifa,Israel
,
Giora Sharf
Affiliations:
Halil Haor non-profit organization for patients with Leukemia and Lymphoma,Halil Haor non-profit organization for patients with Leukemia and Lymphoma,Tel Aviv,Israel
,
Shlomit Norman
Affiliations:
AMEN, Israeli Association of Myeloma Patients,AMEN, Israeli Association of Myeloma Patients,Tel Aviv,Israel
Tamar Tadmor
Affiliations:
Hematology,Bnai Zion Medical Center,Haifa,Israel;Faculty of Medicine,Technion- Israel Institute of Technology,Haifa,Israel
EHA Library. Levy I. 06/09/21; 324430; PB1759
Ilana Levy
Ilana Levy
Contributions
Abstract

Abstract: PB1759

Type: Publication Only

Session title: Quality of life, palliative care, ethics and health economics

Background
The COVID-19 pandemic required reevaluation of the therapeutic approach and added emotional stress for patients with hematological malignancies at high risk of contracting the virus. 

Aims

We aimed to evaluate how it affected such patients during the second lockdown in Israel.

Methods
This national survey included Hebrew-speaking patients with hematological malignancy. This included three tools with 28 items of socio-demographic and medical baseline characteristics, management of hematological disease, and evaluation of emotional coping during COVID-19 pandemic; the Hebrew version of the Patient Health Questionnaire 9; and 3 qualitative open-ended questions. Data was analyzed by mixed methods which combined both quantitative and qualitative thematic analyses.

Results

408 patients responded to the survey. The management of their hematological disease included a decrease in the number of visits to the hematology clinic (37.0%), delay of some treatment schedules (9.1%), and prescription of replacement therapies permitting less visits to the clinic (2.2%). The frequency and intensity of “feeling afraid” regarding COVID-19 infection was increased (mean±SD: 4±1 to 5±2 in a 1-7 Likert scale), and a high rate of depression was recorded, which appeared to be more evident in patients with chronic myeloid leukemia (CML) (p<0.001).

Conclusion
The management of hematological malignancies during pandemics should always take into consideration patients' fears, as well as the development of depression related to isolation and loneliness, in addition to the high risk of severe disease. Patients with CML had a high rate of depression which obviously needs to be managed very carefully during and after the COVID-19 pandemic.

Keyword(s):

Abstract: PB1759

Type: Publication Only

Session title: Quality of life, palliative care, ethics and health economics

Background
The COVID-19 pandemic required reevaluation of the therapeutic approach and added emotional stress for patients with hematological malignancies at high risk of contracting the virus. 

Aims

We aimed to evaluate how it affected such patients during the second lockdown in Israel.

Methods
This national survey included Hebrew-speaking patients with hematological malignancy. This included three tools with 28 items of socio-demographic and medical baseline characteristics, management of hematological disease, and evaluation of emotional coping during COVID-19 pandemic; the Hebrew version of the Patient Health Questionnaire 9; and 3 qualitative open-ended questions. Data was analyzed by mixed methods which combined both quantitative and qualitative thematic analyses.

Results

408 patients responded to the survey. The management of their hematological disease included a decrease in the number of visits to the hematology clinic (37.0%), delay of some treatment schedules (9.1%), and prescription of replacement therapies permitting less visits to the clinic (2.2%). The frequency and intensity of “feeling afraid” regarding COVID-19 infection was increased (mean±SD: 4±1 to 5±2 in a 1-7 Likert scale), and a high rate of depression was recorded, which appeared to be more evident in patients with chronic myeloid leukemia (CML) (p<0.001).

Conclusion
The management of hematological malignancies during pandemics should always take into consideration patients' fears, as well as the development of depression related to isolation and loneliness, in addition to the high risk of severe disease. Patients with CML had a high rate of depression which obviously needs to be managed very carefully during and after the COVID-19 pandemic.

Keyword(s):

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