Contributions
Abstract: PB1751
Type: Publication Only
Session title: Quality of life, palliative care, ethics and health economics
Background
The MD Anderson Symptoms Inventory for acute myeloid leukemia/myelodysplastic syndrome (MDASI-AML/MDS) is one of the specific patient-reported outcome measure (PROM) and widely used to assess the quality of life of acute myeloid leukemia (AML) patients. We translated the original version into Thai (Thai MDASI-AML/MDS) and evaluated its psychometric properties.
Aims
To evaluate the psychometric properties of Thai MDASI-AML/MDS in AML patients.
Methods
After receiving permission, the original MDASI-AML/MDS was translated and cross-culturally adapted to Thai. Sixteen of AML patients were included in the study. Internal consistency was evaluated using Cronbach's alpha and test-retest reliability was analyzed using intraclass correlation coefficient (ICC). Spearman's rank correlation was used to investigate among the subscales of Thai MDASI-AML/MDS and Thai EQ-5D-5L.
Results
All subscales of Thai MDASI-AML/MDS showed an acceptable Cronbach's alpha (0.64-0.92). The test-retest reliability of each subscale was good (ICC = 0.89-0.98). The core symptoms subscale in the Thai MDASI-AML/MDS strongly correlated to the anxiety/ depression subscale in the Thai EQ-5D-5L (r = 0.65, p = 0.0044). The strong correlation was demonstrated between the interference's subscale of the Thai MDASI-AML/MDS and the usual activities subscale of Thai EQ-5D-5L (r = 0.79, p = 0.0002). A weak correlation was found between the MDS/AML specific symptoms subscale in the Thai MDASI-AML/MDS and the pain subscale in the Thai EQ-5D-5L (r = 0.59, p = 0.0121). The Thai MDASI-AML/MDS had strong correlation with Thai EQ-5D-5L (r = 0.76, p = 0.0005).
Conclusion
The Thai MDASI-AML/MDS provides adequate internal consistency in all subscales as well as good construct validity and reliability for Thai patients.
Keyword(s): Acute myeloid leukemia, Quality of life
Abstract: PB1751
Type: Publication Only
Session title: Quality of life, palliative care, ethics and health economics
Background
The MD Anderson Symptoms Inventory for acute myeloid leukemia/myelodysplastic syndrome (MDASI-AML/MDS) is one of the specific patient-reported outcome measure (PROM) and widely used to assess the quality of life of acute myeloid leukemia (AML) patients. We translated the original version into Thai (Thai MDASI-AML/MDS) and evaluated its psychometric properties.
Aims
To evaluate the psychometric properties of Thai MDASI-AML/MDS in AML patients.
Methods
After receiving permission, the original MDASI-AML/MDS was translated and cross-culturally adapted to Thai. Sixteen of AML patients were included in the study. Internal consistency was evaluated using Cronbach's alpha and test-retest reliability was analyzed using intraclass correlation coefficient (ICC). Spearman's rank correlation was used to investigate among the subscales of Thai MDASI-AML/MDS and Thai EQ-5D-5L.
Results
All subscales of Thai MDASI-AML/MDS showed an acceptable Cronbach's alpha (0.64-0.92). The test-retest reliability of each subscale was good (ICC = 0.89-0.98). The core symptoms subscale in the Thai MDASI-AML/MDS strongly correlated to the anxiety/ depression subscale in the Thai EQ-5D-5L (r = 0.65, p = 0.0044). The strong correlation was demonstrated between the interference's subscale of the Thai MDASI-AML/MDS and the usual activities subscale of Thai EQ-5D-5L (r = 0.79, p = 0.0002). A weak correlation was found between the MDS/AML specific symptoms subscale in the Thai MDASI-AML/MDS and the pain subscale in the Thai EQ-5D-5L (r = 0.59, p = 0.0121). The Thai MDASI-AML/MDS had strong correlation with Thai EQ-5D-5L (r = 0.76, p = 0.0005).
Conclusion
The Thai MDASI-AML/MDS provides adequate internal consistency in all subscales as well as good construct validity and reliability for Thai patients.
Keyword(s): Acute myeloid leukemia, Quality of life