Contributions
Abstract: PB1608
Type: Publication Only
Session title: Iron metabolism, deficiency and overload
Background
Iron deficiency anaemia is the most common anaemia worldwide. Parenteral iron administration (Intramuscular or intravascular) is used when per os administration is contraindicated or is insufficient. Intramuscular (IM) iron administration is rarely used because it is painful and can stain the skin. Intravenous (IV) iron administration is time-consuming and anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. A new iron formulation such as sodium ferric gluconate complex and iron sucrose has led intravenous administration to gain ground over iron deficiency anaemia treatment during the last years. It can be administered in a short time with rare adverse events. Despite that, extravasation of iron solution although rare, may happen, leading to permanent skin hyperpigmentation.
Aims
Herein, a case report of iron extravasation among 200 infusions in 15 years, is reported.
Methods
A 51year-old woman with 3 children, Christian in religion with limited meat consumption throughout the year and regular menstruation, presented complaining of tiredness and headache. The laboratory exams revealed iron deficiency anaemia (Hb8gr/dl, MCV70fl, serum ferritin level 4ng/ml). Initially, she was prescribed sulphate iron per os, but she complained of epigastric pain and nausea a few days later. Thus, it was decided to be administered iron IV (Ferric Carboxymaltose). A few minutes after the initiation of the infusion, the woman complained of left arm oedema. The infusion was immediately stopped, and prevention measures were taken.
Results
Six months later, the skin hyperpigmentation in her left arm persists (photo 1).
Conclusion
Conclusion։ Patients who are candidates to receive IV iron administration should be informed about this rare complication. Furthermore, nurses and physicians should be aware of possible iron extravasation and monitor the patient carefully throughout the infusion process; that way, it can be interrupted early if required. As spontaneous regressions of iron skin hyperpigmentation are rarely reported, there is no sufficient data regarding treatment options. Laser therapy could be beneficial in such cases.
Keyword(s):
Abstract: PB1608
Type: Publication Only
Session title: Iron metabolism, deficiency and overload
Background
Iron deficiency anaemia is the most common anaemia worldwide. Parenteral iron administration (Intramuscular or intravascular) is used when per os administration is contraindicated or is insufficient. Intramuscular (IM) iron administration is rarely used because it is painful and can stain the skin. Intravenous (IV) iron administration is time-consuming and anaphylactic-type reactions, including fatalities, have followed the parenteral administration of iron dextran injection. A new iron formulation such as sodium ferric gluconate complex and iron sucrose has led intravenous administration to gain ground over iron deficiency anaemia treatment during the last years. It can be administered in a short time with rare adverse events. Despite that, extravasation of iron solution although rare, may happen, leading to permanent skin hyperpigmentation.
Aims
Herein, a case report of iron extravasation among 200 infusions in 15 years, is reported.
Methods
A 51year-old woman with 3 children, Christian in religion with limited meat consumption throughout the year and regular menstruation, presented complaining of tiredness and headache. The laboratory exams revealed iron deficiency anaemia (Hb8gr/dl, MCV70fl, serum ferritin level 4ng/ml). Initially, she was prescribed sulphate iron per os, but she complained of epigastric pain and nausea a few days later. Thus, it was decided to be administered iron IV (Ferric Carboxymaltose). A few minutes after the initiation of the infusion, the woman complained of left arm oedema. The infusion was immediately stopped, and prevention measures were taken.
Results
Six months later, the skin hyperpigmentation in her left arm persists (photo 1).
Conclusion
Conclusion։ Patients who are candidates to receive IV iron administration should be informed about this rare complication. Furthermore, nurses and physicians should be aware of possible iron extravasation and monitor the patient carefully throughout the infusion process; that way, it can be interrupted early if required. As spontaneous regressions of iron skin hyperpigmentation are rarely reported, there is no sufficient data regarding treatment options. Laser therapy could be beneficial in such cases.
Keyword(s):