Contributions
Abstract: PB1598
Type: Publication Only
Session title: Infections in hematology (incl. supportive care/therapy)
Background
In December 2019, coronavirus disease 2019 (COVID-19) was first found in Wuhan, China caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is currently a pandemic infection reported all around the world. It was previously highlighted that laboratory medicine plays an essential role in the early detection, diagnosis and management of many diseases. Complete blood count is the most available, efficient and economic examination. We compared the data of complete blood count betwen COVID19 pateints and a conrol group.
Aims
This study aims to retrospect and analyze the complete blood count of asymptomatic patients with active COVID-19 infection diagnosed by polymerase chain reaction (PCR) in order to obtain possible indirect key indicators of active disease in asymptomatic patients.
Methods
Sidi Yahya El Gharb Hospital is a field Hospital for asymptomatic patients diagnosed with COVID-19 infection mainly during contact cases screening. Confirmed cases were based on polymerase chain reaction (PCR) nucleic acid testing for SARS-CoV-2 infection. We collected patients from June 20 to July 13, 2020, all of them were isolated and treated according to a national regiment. Patients received hydroxychloroquine 200 mg three times daily for 07 days and azithromycin 500mg once daily for three days. We compared the data of complete blood count, the neutrophil lymphocyte ratio (NLR), the mastocyte lymphocyte ration (MLR) and the platelet lymphocyte ratio (PLR) of our patients with a data of a control group from the Hematologic Laboratory in the Military Hospital Mohammed V of Rabat. The analysis of the data was done using the JAMOVI 1.6.8 statistical programs.
Results
COVID-19 infection was confirmed in 220 patients, no one was febrile. Comparisons made with a control group including 220. The sex ratio was 0,23 vs 0,44. The median values of Leucocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, hemoglobin, platelet, the neutrophil lymphocyte ratio (NLR), the mastocyte lymphocyte ration (MLR) and the platelet lymphocyte ratio (PLR) between the COVID-19 group and the control one was as following : 7110[5495-8683] vs 6500[5375-8000], 3200[2165-4400]vs 3700[2775-2500], 2800[2257-3305]vs 2000[1600-2500], 615[460-780] vs500[400-700], 140[70-230]vs 100[100-200], 50[40-72] vs 0[0-100] , 13,1[12,2-13,9] vs 13,2[12,3-14,1], 282500[224000-353250]vs234000[196000-297750], 1,12[0,765-1,69] vs 1,42[1,19-2,19], 0,207[0,152-0,277]vs0,212[0,211-0,316] and 103[79-126]vs105[97,9-156] .Comparisons made between the two groups revealed a significant difference regarding neutrophils, lymphocyts, basophils, NLR, MLR and PLR (p < 0.05) .
Conclusion
Neutrophil, lymphocyts, basophils, NLR, MLR and PLR can be used to predict n COVID-19 infection in asymptomatic patients .
Keyword(s): COVID-19, Leukocytes, Prediction
Abstract: PB1598
Type: Publication Only
Session title: Infections in hematology (incl. supportive care/therapy)
Background
In December 2019, coronavirus disease 2019 (COVID-19) was first found in Wuhan, China caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is currently a pandemic infection reported all around the world. It was previously highlighted that laboratory medicine plays an essential role in the early detection, diagnosis and management of many diseases. Complete blood count is the most available, efficient and economic examination. We compared the data of complete blood count betwen COVID19 pateints and a conrol group.
Aims
This study aims to retrospect and analyze the complete blood count of asymptomatic patients with active COVID-19 infection diagnosed by polymerase chain reaction (PCR) in order to obtain possible indirect key indicators of active disease in asymptomatic patients.
Methods
Sidi Yahya El Gharb Hospital is a field Hospital for asymptomatic patients diagnosed with COVID-19 infection mainly during contact cases screening. Confirmed cases were based on polymerase chain reaction (PCR) nucleic acid testing for SARS-CoV-2 infection. We collected patients from June 20 to July 13, 2020, all of them were isolated and treated according to a national regiment. Patients received hydroxychloroquine 200 mg three times daily for 07 days and azithromycin 500mg once daily for three days. We compared the data of complete blood count, the neutrophil lymphocyte ratio (NLR), the mastocyte lymphocyte ration (MLR) and the platelet lymphocyte ratio (PLR) of our patients with a data of a control group from the Hematologic Laboratory in the Military Hospital Mohammed V of Rabat. The analysis of the data was done using the JAMOVI 1.6.8 statistical programs.
Results
COVID-19 infection was confirmed in 220 patients, no one was febrile. Comparisons made with a control group including 220. The sex ratio was 0,23 vs 0,44. The median values of Leucocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, hemoglobin, platelet, the neutrophil lymphocyte ratio (NLR), the mastocyte lymphocyte ration (MLR) and the platelet lymphocyte ratio (PLR) between the COVID-19 group and the control one was as following : 7110[5495-8683] vs 6500[5375-8000], 3200[2165-4400]vs 3700[2775-2500], 2800[2257-3305]vs 2000[1600-2500], 615[460-780] vs500[400-700], 140[70-230]vs 100[100-200], 50[40-72] vs 0[0-100] , 13,1[12,2-13,9] vs 13,2[12,3-14,1], 282500[224000-353250]vs234000[196000-297750], 1,12[0,765-1,69] vs 1,42[1,19-2,19], 0,207[0,152-0,277]vs0,212[0,211-0,316] and 103[79-126]vs105[97,9-156] .Comparisons made between the two groups revealed a significant difference regarding neutrophils, lymphocyts, basophils, NLR, MLR and PLR (p < 0.05) .
Conclusion
Neutrophil, lymphocyts, basophils, NLR, MLR and PLR can be used to predict n COVID-19 infection in asymptomatic patients .
Keyword(s): COVID-19, Leukocytes, Prediction