Contributions
Abstract: PB2380
Type: Publication Only
Background
Metabolic syndrome and sarcopenia could often occur in long-term cancer survivors. The first is characterized by a set of cardiovascular risk factors defined by the Cholesterol Education Program Adult Treatment Panel III, which requires simultaneous presence of at least 3, abdominal obesity, hypertension, hyperglycemia, hypertriglyceridemia and low to high density lipoprotein cholesterol (HDL-C), sarcopenia is characterized by a progressive lean mass loss that causes asthenia and malnutrition.
Aims
The aim of this study was to evaluate the prevalence of metabolic syndrome and sarcopenia in lymphoma survivors and provide adequate nutritional support according to Mediterranean Diet.
Methods
Since November 2016 to March 2017, we enrolled 41 consecutive patients (19 women and 22 men) aged between 24 and 76 years in continuous remission of lymphoma for at least 3 years and in current follow-up at our Institutionwithin the “CCM2014 project supported by the Italian Ministry of Health. Nutritional status was assessment by anthropometry (arm, wrist, waist, thigh and calf circumference), plicometry (according to Durnin Womerslay) and body mass index, while glucose, HDL-cholesterol, triglycerides were tested by immunometric assay; For each patient, a customized food plan has been developed based the Mediterranean Diet and they were followed every four weeks.
Results
16/41 (39.0%) of patients of both gender presented a status of obesity (mild, moderate and severe),12/41 (29,2%) were overweight, 11/41 (26,8%) were normal weight and 2/41(4.8%) were underweight; In the women the waist circumference mean was 60.4 cm (range:70-116), while for men the mean was 90.27 cm (range: 69-142). Considering the parameters that characterize the metabolic syndrome, 15/41 patients (36,5%) had at least 3 of these, significantly associated with status of obesity or overweight (p<0.001); Regarding the evaluation of the compartments by plicometry, a significant loss of lean mass and consequent increase in fat mass was and malnutrition observed in the obese and overweight patients respect to normal weight (p <0.001).
Conclusion
More than 60% of long-term lymphoma survivors have a moderate or severe weight gain and 36% have metabolic syndrome associated to sarcopenia; these preliminary data suggest that an early nutritional intervention associated with adequate physical activity could reduce the risk of onset of both complications in lymphoma survivors.
Session topic: 36. Quality of life, palliative care, ethics and health economics
Keyword(s): lymphoma, Metabolic syndrome, Quality of Life
Abstract: PB2380
Type: Publication Only
Background
Metabolic syndrome and sarcopenia could often occur in long-term cancer survivors. The first is characterized by a set of cardiovascular risk factors defined by the Cholesterol Education Program Adult Treatment Panel III, which requires simultaneous presence of at least 3, abdominal obesity, hypertension, hyperglycemia, hypertriglyceridemia and low to high density lipoprotein cholesterol (HDL-C), sarcopenia is characterized by a progressive lean mass loss that causes asthenia and malnutrition.
Aims
The aim of this study was to evaluate the prevalence of metabolic syndrome and sarcopenia in lymphoma survivors and provide adequate nutritional support according to Mediterranean Diet.
Methods
Since November 2016 to March 2017, we enrolled 41 consecutive patients (19 women and 22 men) aged between 24 and 76 years in continuous remission of lymphoma for at least 3 years and in current follow-up at our Institutionwithin the “CCM2014 project supported by the Italian Ministry of Health. Nutritional status was assessment by anthropometry (arm, wrist, waist, thigh and calf circumference), plicometry (according to Durnin Womerslay) and body mass index, while glucose, HDL-cholesterol, triglycerides were tested by immunometric assay; For each patient, a customized food plan has been developed based the Mediterranean Diet and they were followed every four weeks.
Results
16/41 (39.0%) of patients of both gender presented a status of obesity (mild, moderate and severe),12/41 (29,2%) were overweight, 11/41 (26,8%) were normal weight and 2/41(4.8%) were underweight; In the women the waist circumference mean was 60.4 cm (range:70-116), while for men the mean was 90.27 cm (range: 69-142). Considering the parameters that characterize the metabolic syndrome, 15/41 patients (36,5%) had at least 3 of these, significantly associated with status of obesity or overweight (p<0.001); Regarding the evaluation of the compartments by plicometry, a significant loss of lean mass and consequent increase in fat mass was and malnutrition observed in the obese and overweight patients respect to normal weight (p <0.001).
Conclusion
More than 60% of long-term lymphoma survivors have a moderate or severe weight gain and 36% have metabolic syndrome associated to sarcopenia; these preliminary data suggest that an early nutritional intervention associated with adequate physical activity could reduce the risk of onset of both complications in lymphoma survivors.
Session topic: 36. Quality of life, palliative care, ethics and health economics
Keyword(s): lymphoma, Metabolic syndrome, Quality of Life