Contributions
Abstract: PB2523
Type: Publication Only
Background
Vasovagal reactions occur in a small, but significant number of blood donors. These reactions may decrease return donation and disrupt blood collection activities.
Aims
The purpose of this study was to define the contributory role of sex, age, weight, blood pressure in vasovagal reactions with syncope in blood donors.
Methods
Delayed adverse reactions to blood donation occur after the donor left donation site. Their intrinsic gravity and possible complications can be increased by the fact the donor is alone. on this study was to define the contributory role of sex, age, weight, blood pressure, and pulse in vasovagal reactions with syncope in blood donors.
Case controls and random population controls were used in a logistic regression analysis to determine the significance of individual variables to syncopal reactions.
Results
Female donors (RR= 0.41IC (0.23-0.72, p=0.002), Young donors ;<30 years: RR = 1,45 IC (1.22-1.69) P=0.013 (s) , first-time donors (p<.000), low-weight donors <75Kg :RR=1.22 IC (1.06-1.58, p=0.01), and donors with low predonation blood pressure (HR=0.36, p=0.001) had higher absolute donation reaction rates than other donors. as well as the amount of blood taken (fig.1): p=0.013(S)When each variable was adjusted for other variables by regression analysis, age, weight, and donation status (first-time or repeat donor), the most important variableis volume of blood (p=.000). Whenwe compare two periods: 2008-2012 then 2008-2017, we we have noted a net decrease of this type of complications over time, which suggests a better control of the sampling techniques and in particular of the measures of more rigorous selection of the donors (RR=0.45: IC (0.30-0.723), p=0.002.
Conclusion
Donation-related vasovagal syncopal reactions are a multifactorial process determined largely by age, weight, volume delayted and first-time donor status.
Occurrence of a delayed donor reaction is clearly underrated in standard haemovigilance. It remains to be seen whether it have the same impact on donor return as immediate reactions. Considering that delayed reactions are much larger, it might be interesting to take them into account in the evaluation of strategies dedicated to lower immediate reactions.
Session topic: 32. Transfusion medicine
Abstract: PB2523
Type: Publication Only
Background
Vasovagal reactions occur in a small, but significant number of blood donors. These reactions may decrease return donation and disrupt blood collection activities.
Aims
The purpose of this study was to define the contributory role of sex, age, weight, blood pressure in vasovagal reactions with syncope in blood donors.
Methods
Delayed adverse reactions to blood donation occur after the donor left donation site. Their intrinsic gravity and possible complications can be increased by the fact the donor is alone. on this study was to define the contributory role of sex, age, weight, blood pressure, and pulse in vasovagal reactions with syncope in blood donors.
Case controls and random population controls were used in a logistic regression analysis to determine the significance of individual variables to syncopal reactions.
Results
Female donors (RR= 0.41IC (0.23-0.72, p=0.002), Young donors ;<30 years: RR = 1,45 IC (1.22-1.69) P=0.013 (s) , first-time donors (p<.000), low-weight donors <75Kg :RR=1.22 IC (1.06-1.58, p=0.01), and donors with low predonation blood pressure (HR=0.36, p=0.001) had higher absolute donation reaction rates than other donors. as well as the amount of blood taken (fig.1): p=0.013(S)When each variable was adjusted for other variables by regression analysis, age, weight, and donation status (first-time or repeat donor), the most important variableis volume of blood (p=.000). Whenwe compare two periods: 2008-2012 then 2008-2017, we we have noted a net decrease of this type of complications over time, which suggests a better control of the sampling techniques and in particular of the measures of more rigorous selection of the donors (RR=0.45: IC (0.30-0.723), p=0.002.
Conclusion
Donation-related vasovagal syncopal reactions are a multifactorial process determined largely by age, weight, volume delayted and first-time donor status.
Occurrence of a delayed donor reaction is clearly underrated in standard haemovigilance. It remains to be seen whether it have the same impact on donor return as immediate reactions. Considering that delayed reactions are much larger, it might be interesting to take them into account in the evaluation of strategies dedicated to lower immediate reactions.
Session topic: 32. Transfusion medicine