Contributions
Abstract: PB2533
Type: Publication Only
Background
Screening for infectious agents is a vital step in the process of biological qualification of blood donations in virology, preventing the transmission of viral diseases following a blood transfusion or its derivatives.
Aims
The purpose of this study is to determine the seroprevalence of infectious markers in a descriptive, retrospective and monocentric study performed at the Boufarik PTS over a 10-year period (2008-2017).
Methods
This cohort onclude 10,300 donations of blood. Donors received an interview and clinical examination before being selected for a donation. Screening for HIV, HVB and C was performed by enzyme immunoassay based on the Elisa principle and indirect haemagglutination for syphilis.
Results
The prevalence of HIV, HBS, HCV and syphilis serological markers is 0%, 24%, 0.67 and 23%, respectively. By taking two comparative periods: 2008-2012 (n = 4139 donations) and 2013-2017 (n = 6161 donations): there is an increase in the number of positive cases for the hepatitis B virus: n = 07 (2008- 2012) versus n = 18 (2013-2017): RR = .69 (.37-1.30), p = .13 (NS) fig.1. An increase in the number of positive cases for hepatitis C virus: n = 02 (2008-2012) vs n = 05 (20132017): RR = .89 (.21-3.73), p = .45 (NS) fig.2. A stable number of positive cases for the syphilis virus: n = 12 (2008-2012) versus n = 12 (2013-2017): RR = 1.49 (.663.31), p = .16 (NS) fig.3
Conclusion
These results show that the prevalence of viral infections is stable over time among blood donors in our region. This is due to the introduction of a quality assurance system, the choice of the collection site, the selection of donors and finally the improvement of the quality of screening, which has helped to ensure optimal blood safety.
Session topic: 32. Transfusion medicine
Keyword(s): HIV
Abstract: PB2533
Type: Publication Only
Background
Screening for infectious agents is a vital step in the process of biological qualification of blood donations in virology, preventing the transmission of viral diseases following a blood transfusion or its derivatives.
Aims
The purpose of this study is to determine the seroprevalence of infectious markers in a descriptive, retrospective and monocentric study performed at the Boufarik PTS over a 10-year period (2008-2017).
Methods
This cohort onclude 10,300 donations of blood. Donors received an interview and clinical examination before being selected for a donation. Screening for HIV, HVB and C was performed by enzyme immunoassay based on the Elisa principle and indirect haemagglutination for syphilis.
Results
The prevalence of HIV, HBS, HCV and syphilis serological markers is 0%, 24%, 0.67 and 23%, respectively. By taking two comparative periods: 2008-2012 (n = 4139 donations) and 2013-2017 (n = 6161 donations): there is an increase in the number of positive cases for the hepatitis B virus: n = 07 (2008- 2012) versus n = 18 (2013-2017): RR = .69 (.37-1.30), p = .13 (NS) fig.1. An increase in the number of positive cases for hepatitis C virus: n = 02 (2008-2012) vs n = 05 (20132017): RR = .89 (.21-3.73), p = .45 (NS) fig.2. A stable number of positive cases for the syphilis virus: n = 12 (2008-2012) versus n = 12 (2013-2017): RR = 1.49 (.663.31), p = .16 (NS) fig.3
Conclusion
These results show that the prevalence of viral infections is stable over time among blood donors in our region. This is due to the introduction of a quality assurance system, the choice of the collection site, the selection of donors and finally the improvement of the quality of screening, which has helped to ensure optimal blood safety.
Session topic: 32. Transfusion medicine
Keyword(s): HIV