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EPIDEMIOLOGICAL DATA ON POLYCYTHEMIA VERA IN ALBANIA (1999 - 2014)
Author(s): ,
Adela Perolla
Affiliations:
Internal Medicine, Hematology,UHC " Mother Teresa",Tirana,Albania
,
Tatjana Caja
Affiliations:
Internal Medicine, Hematology,UHC " Mother Teresa",Tirana,Albania
,
Polikron Pulluqi
Affiliations:
internal Medicine,UHC " Mother Teresa",Tirana,Albania
,
Elsuarta Calliku
Affiliations:
Internal Medicine ,Hematology,UHC " Mother Teresa" ,Tirana,Albania
,
Arben Ivanaj
Affiliations:
internal Medicine Hematology,UHC " Mother Teresa",Tirana,Albania
,
Alma Cili
Affiliations:
internal Medicine Hematology,UHC " Mother Teresa",Tirana,Albania
Arjan Pushi
Affiliations:
Internal Medicine Hematology,UHC" Mother Teresa",Tirana,Albania
(Abstract release date: 05/17/18) EHA Library. Perolla A. 06/14/18; 216542; PB2302
Adela Perolla
Adela Perolla
Contributions
Abstract

Abstract: PB2302

Type: Publication Only

Background

Polycythemia Vera (PV) is a chronic myeloproliferative disease characterized by the elevation of the number of red blood cells. It is more common in males over 60 years old, but it can be present in every age group. An uncontrolled PV can induce a large number of thrombotic events putting in a high risk the lives of those patients. 

Aims

To evaluate the incidence and sex-related incidence of PV in Albanian population during the period of time from 1999-2014 and to assess the emergency events at the moment of the diagnosis. 

Methods

We collected and studied the data of all the patients more than 18 years old hospitalised and diagnosed with PV in the UHC “Mother Teresa” during the period from 1999-2014. SSPS 20.0 was used for the statistical analyses.

Results

According to the data collected and analyzed in the period from 1999-2014, the total number of the patients diagnosed with PV was 119 patients. From all the patients diagnosed with PV, 71 (60%) were males and 48 (40%) females. Only 23% of them have been presented in the Emergency Unit. 61% of all those patients presented in the Emergency Unit presented cardiovascular diseases (arterial hypertension, CAD, myocardial infarction), 12% neurological complications (stroke, convulsions etc..) 12% VTE (pulmonary, portal system, etc), 8% diabetes mellitus untreated (only one patient presented in the emergency with primary hypothyreosis) and 7% melena.

The annual incidence of PV in Albania results in about 0,24 new cases per 100,000 inhabitants with an augmentation during 2006 (0,56 new cases per 100,000 inhabitants). The incidence was higher in males compared to females with a ratio 1,51/1. The annual incidence for males and females was respectively 0,29 new cases / 100 000 inhabitants and 0,19 new PV cases / 100000 inhabitants.  

Conclusion

PV is a disease presented in Albania with about 7,4new cases per 100.000 inhabitants and with an incidence of around 0,24 new cases per 100,000 inhabitants affecting more males than females with a ratio 1,51/1. Mostly the patients went to the haematologist through the consultations and only 23% of them was diagnosed after presenting in the Emergency Unit predominantly with cardiovascular complications, before being diagnosed with PV. The correct diagnosis and management of those patients reduces the risk of thrombotic events and improves the prognosis.  

Session topic: 16. Myeloproliferative neoplasms - Clinical

Keyword(s): epidemiology, Incidence, Polycythemia vera, Thromboembolic events

Abstract: PB2302

Type: Publication Only

Background

Polycythemia Vera (PV) is a chronic myeloproliferative disease characterized by the elevation of the number of red blood cells. It is more common in males over 60 years old, but it can be present in every age group. An uncontrolled PV can induce a large number of thrombotic events putting in a high risk the lives of those patients. 

Aims

To evaluate the incidence and sex-related incidence of PV in Albanian population during the period of time from 1999-2014 and to assess the emergency events at the moment of the diagnosis. 

Methods

We collected and studied the data of all the patients more than 18 years old hospitalised and diagnosed with PV in the UHC “Mother Teresa” during the period from 1999-2014. SSPS 20.0 was used for the statistical analyses.

Results

According to the data collected and analyzed in the period from 1999-2014, the total number of the patients diagnosed with PV was 119 patients. From all the patients diagnosed with PV, 71 (60%) were males and 48 (40%) females. Only 23% of them have been presented in the Emergency Unit. 61% of all those patients presented in the Emergency Unit presented cardiovascular diseases (arterial hypertension, CAD, myocardial infarction), 12% neurological complications (stroke, convulsions etc..) 12% VTE (pulmonary, portal system, etc), 8% diabetes mellitus untreated (only one patient presented in the emergency with primary hypothyreosis) and 7% melena.

The annual incidence of PV in Albania results in about 0,24 new cases per 100,000 inhabitants with an augmentation during 2006 (0,56 new cases per 100,000 inhabitants). The incidence was higher in males compared to females with a ratio 1,51/1. The annual incidence for males and females was respectively 0,29 new cases / 100 000 inhabitants and 0,19 new PV cases / 100000 inhabitants.  

Conclusion

PV is a disease presented in Albania with about 7,4new cases per 100.000 inhabitants and with an incidence of around 0,24 new cases per 100,000 inhabitants affecting more males than females with a ratio 1,51/1. Mostly the patients went to the haematologist through the consultations and only 23% of them was diagnosed after presenting in the Emergency Unit predominantly with cardiovascular complications, before being diagnosed with PV. The correct diagnosis and management of those patients reduces the risk of thrombotic events and improves the prognosis.  

Session topic: 16. Myeloproliferative neoplasms - Clinical

Keyword(s): epidemiology, Incidence, Polycythemia vera, Thromboembolic events

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