Contributions
Abstract: PB1650
Type: Publication Only
Background
Vena cava superior syndrome (VCSS) comprises various symptoms of compression of vena cava superior. The resulting increased venous pressure in the upper body may cause edema of the head and neck associated with cyanosis, pletore and distended subcutaneous vessels.
Aims
VCSS is rare in childhood. Therefore, we planned this retrospective study.
Methods
The retrospective study was carried out on the children with mediastinal tumors in the department of pediatric hematology-oncology, Erciyes University Medical School, from january 2010 to december 2017. Diagnostic procedures included hematological investigations, chest radiography, thoracic computed tomography, echocardiography and lymph node or mediastinal biopsy.
Results
19 (five were female) of 41 patients with mediastinal tumors had VCSS. Mean age of the patients with VCSS was 8.57 years (range:1-17 years). Diagnosis included Hodgkin’s disease (HD) in 7,non-Hodgkin’s lymphoma (NHL) in 6, acute T- lymphoblastic leukemia in 5, neuroblastoma and anaplastic round cell sarcoma in one each respectively. All the 19 patients had dyspnea, venous distention and mediastinal widening. Two patients with NHL had bilateral pleural effusion. All patients received intravenous corticosteroids (0.6 mg/kg dexamethasone). Furthermore, the patient with anaplastic round cell sarcoma recevied emergency radiotherapy. All patients received chemothepy and followed up in our PHO clinic. No patients died because of VCSS.
Conclusion
Compression of structures in the superior mediastinum is known as VCSS that it is a medical emergency requiring urgent treatment. In this retrospective study, we found that the most common cause of VCSS was HD as different from literature.
Session topic: 2. Acute lymphoblastic leukemia - Clinical
Keyword(s): Acute lymphoblastic leukemia
Abstract: PB1650
Type: Publication Only
Background
Vena cava superior syndrome (VCSS) comprises various symptoms of compression of vena cava superior. The resulting increased venous pressure in the upper body may cause edema of the head and neck associated with cyanosis, pletore and distended subcutaneous vessels.
Aims
VCSS is rare in childhood. Therefore, we planned this retrospective study.
Methods
The retrospective study was carried out on the children with mediastinal tumors in the department of pediatric hematology-oncology, Erciyes University Medical School, from january 2010 to december 2017. Diagnostic procedures included hematological investigations, chest radiography, thoracic computed tomography, echocardiography and lymph node or mediastinal biopsy.
Results
19 (five were female) of 41 patients with mediastinal tumors had VCSS. Mean age of the patients with VCSS was 8.57 years (range:1-17 years). Diagnosis included Hodgkin’s disease (HD) in 7,non-Hodgkin’s lymphoma (NHL) in 6, acute T- lymphoblastic leukemia in 5, neuroblastoma and anaplastic round cell sarcoma in one each respectively. All the 19 patients had dyspnea, venous distention and mediastinal widening. Two patients with NHL had bilateral pleural effusion. All patients received intravenous corticosteroids (0.6 mg/kg dexamethasone). Furthermore, the patient with anaplastic round cell sarcoma recevied emergency radiotherapy. All patients received chemothepy and followed up in our PHO clinic. No patients died because of VCSS.
Conclusion
Compression of structures in the superior mediastinum is known as VCSS that it is a medical emergency requiring urgent treatment. In this retrospective study, we found that the most common cause of VCSS was HD as different from literature.
Session topic: 2. Acute lymphoblastic leukemia - Clinical
Keyword(s): Acute lymphoblastic leukemia