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THE IMPACT OF GESTATIONAL THROMBOCYTOPENIA IN NEWBORNS
Author(s): ,
Sorica Cristina
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
,
Pescaru Monica
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
,
Budai Ema
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
,
Cismas Sonia
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
,
Lighezan Diana
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
,
Samfireag Miruna
Affiliations:
Hematology,Municipality Emergency Hospital of Timisoara,Timisoara,Romania
,
Grozavescu Alexandru
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
Potre Ovidiu
Affiliations:
Hematology,University of Medicine and Pharmacy "Victor Babes" Timisoara,Timisoara,Romania
(Abstract release date: 05/17/18) EHA Library. Cristina P. 06/14/18; 216141; PB2364
Potre Cristina
Potre Cristina
Contributions
Abstract

Abstract: PB2364

Type: Publication Only

Background
Thrombocytopenia develops rarely during pregnancy or in the immediate postpartum period. It may develop secondary as a biomarker of a coexisting disorder or it may be also idiopathic.

Aims
The aim of this study was to determine the impact that gestational thrombocytopenia (GT) has on the pregnancy evolution as well as on the newborn’s health.

Methods
This is a retrospective study on 40 women who developed thrombocytopenia during pregnancy. Data was obtained from their medical files. We selected data from when they were at least 30 weeks of pregnancy.

Results
From the total of 40 women , 26 (65%) developed mild thrombocytopenia (platelets over 100.000) and 14 (35%) developed mild thrombocytopenia (platelets between 50.000 and 100.000). From the total of patients who developed mild thrombocytopenia, 73,07% presented a very mild oscilation in the platelets values before giving birth while 26,93% presented a significant decrease in platelets count with about 50.000. The situation was different in case of women who developed moderate anemia. The majority of them (71,42%) developed severe thrombocytopenia and cortison therapy was given . What concerns the newborns of mothers presenting mild anemia, only 15,38% of them presented thrombocytopenia and it recovered in a few weeks without therapy. On the other hand, the majority of newborns (57,14%) whose mothers presented moderate thrombocytopenia developed persistent thrombocytopenia with platelets in continuous decrease and further investigations were performed.

Conclusion
This study reveals that newborns from mothers who developed  moderate gestational thrombocytopenia have better chances to develop thrombocytopenia.

Session topic: 33.  Platelets disorders

Keyword(s): Pregnancy, Thrombocytopenia

Abstract: PB2364

Type: Publication Only

Background
Thrombocytopenia develops rarely during pregnancy or in the immediate postpartum period. It may develop secondary as a biomarker of a coexisting disorder or it may be also idiopathic.

Aims
The aim of this study was to determine the impact that gestational thrombocytopenia (GT) has on the pregnancy evolution as well as on the newborn’s health.

Methods
This is a retrospective study on 40 women who developed thrombocytopenia during pregnancy. Data was obtained from their medical files. We selected data from when they were at least 30 weeks of pregnancy.

Results
From the total of 40 women , 26 (65%) developed mild thrombocytopenia (platelets over 100.000) and 14 (35%) developed mild thrombocytopenia (platelets between 50.000 and 100.000). From the total of patients who developed mild thrombocytopenia, 73,07% presented a very mild oscilation in the platelets values before giving birth while 26,93% presented a significant decrease in platelets count with about 50.000. The situation was different in case of women who developed moderate anemia. The majority of them (71,42%) developed severe thrombocytopenia and cortison therapy was given . What concerns the newborns of mothers presenting mild anemia, only 15,38% of them presented thrombocytopenia and it recovered in a few weeks without therapy. On the other hand, the majority of newborns (57,14%) whose mothers presented moderate thrombocytopenia developed persistent thrombocytopenia with platelets in continuous decrease and further investigations were performed.

Conclusion
This study reveals that newborns from mothers who developed  moderate gestational thrombocytopenia have better chances to develop thrombocytopenia.

Session topic: 33.  Platelets disorders

Keyword(s): Pregnancy, Thrombocytopenia

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