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LIBERAL VS RESTRICTIVE COMPARATIVE TRANSFUSIONAL STUDY IN ONCOLOGICAL POPULATION
Author(s): ,
M. Inés Touzón Andión
Affiliations:
Transfusion, Centro Oncológico de Galicia,La Coruña,Spain
,
MJ Gestal
Affiliations:
Transfusion,Centro Oncológico de Galicia,La Coruña,Spain
,
AM Varela
Affiliations:
Transfusion,Centro Oncológico de Galicia, La Coruña, Spain
,
MF Castro
Affiliations:
Transfusion,Centro Oncológico de Galicia,La Coruña, Spain
,
CS Moinelo
Affiliations:
Transfusion,Centro Oncológico de Galicia, La Coruña, Spain
Roberto García de Villaescusa
Affiliations:
Transfusion,Centro Oncológico de Galicia, La Coruña, Spain
(Abstract release date: 05/18/17) EHA Library. TOUZON ANDION M. 05/18/17; 182948; PB2235
MARÍA INÉS TOUZON ANDION
MARÍA INÉS TOUZON ANDION
Contributions
Abstract

Abstract: PB2235

Type: Publication Only

Background
Allogeneic transfusion therapy is perhaps one of the most widely used treatments without good evidence support, despite many years of application in clinical practice. This, coupled with blood shortages, the impossibility of achieving zero risk, the lack of evidence that transfusion may increase consumption or decrease tissue oxygen debt and the existence of an association with an increase in morbidity and mortality have favoured that we join efforts towards its optimal use.

Aims
Optimal use in our adult oncological population and evidence that restrictive transfusion (TR, Hb 7-9 grs / dl) is not greater or lowerto the liberal transfusion (TL, Hb 8-10 grs / dl), keeping hemoglobin in safe levels for the patient.

Methods
A research was performed from October 1st, 2015 through December 31st, 2016. We analyzed the proportion of patients receiving packed red cells (CH) and the number of units transfused as well as post-transfusion control in order to describe the outcome of the CH versus TL strategies in the cancer population under the study.

Results

Transfusional Therapy
Patients (Nº)
Hb Pre (X-)
Hb Post (X-)
yield /CH (grs/dl)
RT
192
8,1
9,1
1,0
LT
97
7,4
9,4
1,0
PWC
22
8,0
-
-
TPT
311
7,8
9,2
1,0
X- RBC transfused: 1,3
Hb Pre: Pre-transfusional haemoglobin; Hb Post: Post-transfusional haemoglobin; PWC: Patients without post transfusion Hblevel; TPT: Total Patients Transfused.
X-: half haemoglobin

Conclusion
The results obtained in our series of 311 cancer patients indicate that the restrictive strategy has been equally effective and probably superior to the liberal one maintaining Hb at a safe level in each patient, as well as quality of life and comfort in a subgroup with advanced and terminal cancer.

Session topic: 30. Transfusion medicine

Keyword(s): transfusion, Medical patients, Hemoglobin

Abstract: PB2235

Type: Publication Only

Background
Allogeneic transfusion therapy is perhaps one of the most widely used treatments without good evidence support, despite many years of application in clinical practice. This, coupled with blood shortages, the impossibility of achieving zero risk, the lack of evidence that transfusion may increase consumption or decrease tissue oxygen debt and the existence of an association with an increase in morbidity and mortality have favoured that we join efforts towards its optimal use.

Aims
Optimal use in our adult oncological population and evidence that restrictive transfusion (TR, Hb 7-9 grs / dl) is not greater or lowerto the liberal transfusion (TL, Hb 8-10 grs / dl), keeping hemoglobin in safe levels for the patient.

Methods
A research was performed from October 1st, 2015 through December 31st, 2016. We analyzed the proportion of patients receiving packed red cells (CH) and the number of units transfused as well as post-transfusion control in order to describe the outcome of the CH versus TL strategies in the cancer population under the study.

Results

Transfusional Therapy
Patients (Nº)
Hb Pre (X-)
Hb Post (X-)
yield /CH (grs/dl)
RT
192
8,1
9,1
1,0
LT
97
7,4
9,4
1,0
PWC
22
8,0
-
-
TPT
311
7,8
9,2
1,0
X- RBC transfused: 1,3
Hb Pre: Pre-transfusional haemoglobin; Hb Post: Post-transfusional haemoglobin; PWC: Patients without post transfusion Hblevel; TPT: Total Patients Transfused.
X-: half haemoglobin

Conclusion
The results obtained in our series of 311 cancer patients indicate that the restrictive strategy has been equally effective and probably superior to the liberal one maintaining Hb at a safe level in each patient, as well as quality of life and comfort in a subgroup with advanced and terminal cancer.

Session topic: 30. Transfusion medicine

Keyword(s): transfusion, Medical patients, Hemoglobin

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