Contributions
Abstract: PB2012
Type: Publication Only
Background
Renal impairment (RI), defined as serum creatinine above upper normal limit or >2 mg/dl or a estimated glomerular filtration rate (eGFR) <60 ml/min/1,73m2, is one of the most common complications of MM, and it is associated with an increased risk of early death. The incidence of RI at MM diagnosis ranges from 20% to 50%, while its comparison occurred in 60 % MM patients (pts). In this scenario tempestive diagnosis of RI in MM pts and exclusion of possible alternative causes of RI (like amiloydosis, diabetes or MIDD) are essential.
Aims
Methods
Results
From March to December 2016 we admitted 57 pts with RI and monoclonal component (29 F, 28 M, 41-83 yrs range), 20 are known MM pts and 37 de novo pts. We diagnosed 11 de novo MM, 13 knowed MM with a de novo RI, 12 diabetes related RI, 3 amyloidosis, 16 other causes.
Conclusion
The implementation of the International Myeloma Working Group Reccomendations in a routine clinical practice confirmed its feasibility and utility in the optimal workout of MM pts. We obtained diagnosis of RI within 4 days, both in known and in de novo MM pts, with a positive impact on reduced hospitalization, uncessary dyalisis and steroids overtreatment.
Session topic: 14. Myeloma and other monoclonal gammopathies - Clinical
Keyword(s): Renal impairment, Multiple Myeloma
Abstract: PB2012
Type: Publication Only
Background
Renal impairment (RI), defined as serum creatinine above upper normal limit or >2 mg/dl or a estimated glomerular filtration rate (eGFR) <60 ml/min/1,73m2, is one of the most common complications of MM, and it is associated with an increased risk of early death. The incidence of RI at MM diagnosis ranges from 20% to 50%, while its comparison occurred in 60 % MM patients (pts). In this scenario tempestive diagnosis of RI in MM pts and exclusion of possible alternative causes of RI (like amiloydosis, diabetes or MIDD) are essential.
Aims
Methods
Results
From March to December 2016 we admitted 57 pts with RI and monoclonal component (29 F, 28 M, 41-83 yrs range), 20 are known MM pts and 37 de novo pts. We diagnosed 11 de novo MM, 13 knowed MM with a de novo RI, 12 diabetes related RI, 3 amyloidosis, 16 other causes.
Conclusion
The implementation of the International Myeloma Working Group Reccomendations in a routine clinical practice confirmed its feasibility and utility in the optimal workout of MM pts. We obtained diagnosis of RI within 4 days, both in known and in de novo MM pts, with a positive impact on reduced hospitalization, uncessary dyalisis and steroids overtreatment.
Session topic: 14. Myeloma and other monoclonal gammopathies - Clinical
Keyword(s): Renal impairment, Multiple Myeloma