Contributions
Abstract: PB1747
Type: Publication Only
Background
In life threatening hemorrhage such as brain and abdomen, several important factors are affect for improving the survival. One tenth (223) of hemophilia patients in Korea lived in Daegu city and Kyungpook province and have treated in our regional treatment center.
Aims
We reviewed the result of life threatening hemorrhage and our unique care of hemophilia patients for 34 years.
Methods
Korea Hemophilia Foundation was established in 1991. After that all factor concentrates were free to all hemophilia patients. Home treatment are available for rapid administration of factor concentrate of full required amount. Rapid transportation to emergency room are available for immediate operation. Hot line of mobile phone between patient and doctor for 24 hours are available for emergency care. Monthly group education has done. Prophylactic treatment was started to all who had a life threatening hemorrhage history in our hospital since 1996. But HIRA permitted officially since 2011.
Results
Thirty five events were intracranial hemorrhage in 17, general surgery in 9 and orthopedic surgery in 9. Age distribution was 0-32 yr (mean; 24.8 yr). Severity was severe (16), moderate (7) and mild (5). Time interval between first symptom and arrival at ER were 15 min to 10 days (mean; 1.7days). We confirmed in vivo factor activity within permissible level in all patients. All recovered from hemorrhage or surgery and are healthy, but one had limping gate and one had mild neurologic sequela for more than 10 years follow-up period.
Conclusion
Education, financial support, home and prophylactic treatment, hot-line, individual pharmacokinetics with effective blood level and fresh concentrate during continuous infusion are important factors to improve the survival of surgery case.
Session topic: 33. Bleeding disorders (congenital and acquired)
Keyword(s): Hemorrhage, Hemophilia
Abstract: PB1747
Type: Publication Only
Background
In life threatening hemorrhage such as brain and abdomen, several important factors are affect for improving the survival. One tenth (223) of hemophilia patients in Korea lived in Daegu city and Kyungpook province and have treated in our regional treatment center.
Aims
We reviewed the result of life threatening hemorrhage and our unique care of hemophilia patients for 34 years.
Methods
Korea Hemophilia Foundation was established in 1991. After that all factor concentrates were free to all hemophilia patients. Home treatment are available for rapid administration of factor concentrate of full required amount. Rapid transportation to emergency room are available for immediate operation. Hot line of mobile phone between patient and doctor for 24 hours are available for emergency care. Monthly group education has done. Prophylactic treatment was started to all who had a life threatening hemorrhage history in our hospital since 1996. But HIRA permitted officially since 2011.
Results
Thirty five events were intracranial hemorrhage in 17, general surgery in 9 and orthopedic surgery in 9. Age distribution was 0-32 yr (mean; 24.8 yr). Severity was severe (16), moderate (7) and mild (5). Time interval between first symptom and arrival at ER were 15 min to 10 days (mean; 1.7days). We confirmed in vivo factor activity within permissible level in all patients. All recovered from hemorrhage or surgery and are healthy, but one had limping gate and one had mild neurologic sequela for more than 10 years follow-up period.
Conclusion
Education, financial support, home and prophylactic treatment, hot-line, individual pharmacokinetics with effective blood level and fresh concentrate during continuous infusion are important factors to improve the survival of surgery case.
Session topic: 33. Bleeding disorders (congenital and acquired)
Keyword(s): Hemorrhage, Hemophilia