TRANSFUSION PROTOCOLS OF BLOOD CENTRE OF ASL CASERTA (MANAGEMENT AND MONITORING)
(Abstract release date: 05/19/16)
EHA Library. Dell'aversana M. 06/09/16; 135125; PB2225
Dr. Maria Rosaria Dell'aversana
Contributions
Contributions
Abstract
Abstract: PB2225
Type: Publication Only
Background
The red blood cell is an immunologically competent cell for the presence of various exposed antigens, inherited genetically. Transfusion is a medical procedure extremely important, and certainly not without risks. Our Trasfusion Centre implemented transfusion protocols to ensure that all patients have best treatment possible; these protocols provide for the identification of two groups of patients:chronic and acute. The first transfusing compatibility with the Rh, kell Duffy, Kidd, MNS systems with apheresis or filtered red blood cell, the seconds one with Rh and Kell systems compatibility, by decomposition of red blood cells. This is possible thanks to the availability of blood guaranteed by the excellent cooperation with voluntary associations, particularly for the production of red blood cells by apheresis.
Aims
The aim of our study was to evaluate the effectiveness of our transfusion protocols and their impact on health patients (immunological complications)
Methods
A retrospective study was done on all patients transfused in 2015 year, the patients were divided in chronic and acute and we studied the percentage of immunization and the most frequent antibody (computer system Eliot Enginnering Health)
Results
In the year 2015 were carried out 14,277 transfusions to 7000 patients (2500 chronic and 4500 acute). There were no immunizations in chronic patients while in the acute patient the percentage was 0.6%. The identified antibodies were: anti-D: 36.4%, anti-K : 27%, anti-E : 15%, anti-C: 1%, anti-c :6%, anti-e: 3%, anti FyA :2%, anti-Fyb: 1%, anti M : 3.4%, anti LeA :2.2%.
Conclusion
The results show that the cases of immunizations are all at the expense of acute patients, this confirming as the transfusion protocols guarantee the best possible therapy trying to preserve all chronic patients from ineffective transfusions. The frequencies of the detected antibodies reflect the immunogenicity scale. The choice to transfuse the chronich patients respecting such scale have preserved to immunizations. These protocols may seem expensive for the company budget assigned to the blood transfusion service, the savings are long-term evident in reality as it reduces the number of immunized patients and then the cost of their management.
Session topic: E-poster
Type: Publication Only
Background
The red blood cell is an immunologically competent cell for the presence of various exposed antigens, inherited genetically. Transfusion is a medical procedure extremely important, and certainly not without risks. Our Trasfusion Centre implemented transfusion protocols to ensure that all patients have best treatment possible; these protocols provide for the identification of two groups of patients:chronic and acute. The first transfusing compatibility with the Rh, kell Duffy, Kidd, MNS systems with apheresis or filtered red blood cell, the seconds one with Rh and Kell systems compatibility, by decomposition of red blood cells. This is possible thanks to the availability of blood guaranteed by the excellent cooperation with voluntary associations, particularly for the production of red blood cells by apheresis.
Aims
The aim of our study was to evaluate the effectiveness of our transfusion protocols and their impact on health patients (immunological complications)
Methods
A retrospective study was done on all patients transfused in 2015 year, the patients were divided in chronic and acute and we studied the percentage of immunization and the most frequent antibody (computer system Eliot Enginnering Health)
Results
In the year 2015 were carried out 14,277 transfusions to 7000 patients (2500 chronic and 4500 acute). There were no immunizations in chronic patients while in the acute patient the percentage was 0.6%. The identified antibodies were: anti-D: 36.4%, anti-K : 27%, anti-E : 15%, anti-C: 1%, anti-c :6%, anti-e: 3%, anti FyA :2%, anti-Fyb: 1%, anti M : 3.4%, anti LeA :2.2%.
Conclusion
The results show that the cases of immunizations are all at the expense of acute patients, this confirming as the transfusion protocols guarantee the best possible therapy trying to preserve all chronic patients from ineffective transfusions. The frequencies of the detected antibodies reflect the immunogenicity scale. The choice to transfuse the chronich patients respecting such scale have preserved to immunizations. These protocols may seem expensive for the company budget assigned to the blood transfusion service, the savings are long-term evident in reality as it reduces the number of immunized patients and then the cost of their management.
Session topic: E-poster
Abstract: PB2225
Type: Publication Only
Background
The red blood cell is an immunologically competent cell for the presence of various exposed antigens, inherited genetically. Transfusion is a medical procedure extremely important, and certainly not without risks. Our Trasfusion Centre implemented transfusion protocols to ensure that all patients have best treatment possible; these protocols provide for the identification of two groups of patients:chronic and acute. The first transfusing compatibility with the Rh, kell Duffy, Kidd, MNS systems with apheresis or filtered red blood cell, the seconds one with Rh and Kell systems compatibility, by decomposition of red blood cells. This is possible thanks to the availability of blood guaranteed by the excellent cooperation with voluntary associations, particularly for the production of red blood cells by apheresis.
Aims
The aim of our study was to evaluate the effectiveness of our transfusion protocols and their impact on health patients (immunological complications)
Methods
A retrospective study was done on all patients transfused in 2015 year, the patients were divided in chronic and acute and we studied the percentage of immunization and the most frequent antibody (computer system Eliot Enginnering Health)
Results
In the year 2015 were carried out 14,277 transfusions to 7000 patients (2500 chronic and 4500 acute). There were no immunizations in chronic patients while in the acute patient the percentage was 0.6%. The identified antibodies were: anti-D: 36.4%, anti-K : 27%, anti-E : 15%, anti-C: 1%, anti-c :6%, anti-e: 3%, anti FyA :2%, anti-Fyb: 1%, anti M : 3.4%, anti LeA :2.2%.
Conclusion
The results show that the cases of immunizations are all at the expense of acute patients, this confirming as the transfusion protocols guarantee the best possible therapy trying to preserve all chronic patients from ineffective transfusions. The frequencies of the detected antibodies reflect the immunogenicity scale. The choice to transfuse the chronich patients respecting such scale have preserved to immunizations. These protocols may seem expensive for the company budget assigned to the blood transfusion service, the savings are long-term evident in reality as it reduces the number of immunized patients and then the cost of their management.
Session topic: E-poster
Type: Publication Only
Background
The red blood cell is an immunologically competent cell for the presence of various exposed antigens, inherited genetically. Transfusion is a medical procedure extremely important, and certainly not without risks. Our Trasfusion Centre implemented transfusion protocols to ensure that all patients have best treatment possible; these protocols provide for the identification of two groups of patients:chronic and acute. The first transfusing compatibility with the Rh, kell Duffy, Kidd, MNS systems with apheresis or filtered red blood cell, the seconds one with Rh and Kell systems compatibility, by decomposition of red blood cells. This is possible thanks to the availability of blood guaranteed by the excellent cooperation with voluntary associations, particularly for the production of red blood cells by apheresis.
Aims
The aim of our study was to evaluate the effectiveness of our transfusion protocols and their impact on health patients (immunological complications)
Methods
A retrospective study was done on all patients transfused in 2015 year, the patients were divided in chronic and acute and we studied the percentage of immunization and the most frequent antibody (computer system Eliot Enginnering Health)
Results
In the year 2015 were carried out 14,277 transfusions to 7000 patients (2500 chronic and 4500 acute). There were no immunizations in chronic patients while in the acute patient the percentage was 0.6%. The identified antibodies were: anti-D: 36.4%, anti-K : 27%, anti-E : 15%, anti-C: 1%, anti-c :6%, anti-e: 3%, anti FyA :2%, anti-Fyb: 1%, anti M : 3.4%, anti LeA :2.2%.
Conclusion
The results show that the cases of immunizations are all at the expense of acute patients, this confirming as the transfusion protocols guarantee the best possible therapy trying to preserve all chronic patients from ineffective transfusions. The frequencies of the detected antibodies reflect the immunogenicity scale. The choice to transfuse the chronich patients respecting such scale have preserved to immunizations. These protocols may seem expensive for the company budget assigned to the blood transfusion service, the savings are long-term evident in reality as it reduces the number of immunized patients and then the cost of their management.
Session topic: E-poster
{{ help_message }}
{{filter}}