COMPARISON AMONG PERIODS FOR HEMOGLOBIN EQUILIBRATION AFTER BLOOD TRANSFUSION
(Abstract release date: 05/19/16)
EHA Library. Tantiworawit A. 06/09/16; 135121; PB2221
Dr. Adisak Tantiworawit
Contributions
Contributions
Abstract
Abstract: PB2221
Type: Publication Only
Background
Target hemoglobin (Hb) varies among different clinical situations but mainly at 7 g/dL. Many institutes include ours follow Hb and hematocrit (Hct) after transfusion at 4 hours for achieving target level. But previous study showed that equilibration after red cell transfusion was at 24 hours. We sought to find out the appropriate time point after red cell transfusion. The result may help physicians to provide earlier and proper treatment.
Aims
This research was aimed to determine the equilibration time point of Hb and Hct after red cell transfusion.
Methods
This is a prospective randomized trial conducted from December 2014 to August 2015 at Chiang Mai University Hospital. Inclusion criteria was adult patient who received 1 unit of red cell without active bleeding and hemolysis. Number of patient was calculated by match pair method from previous study. Hb and Hct were measured at baseline before transfusion. Patients were randomized into 3 groups according to baseline characteristics to follow Hb and Hct at 1, 4 or 24 hours after transfusion. Mean difference of Hb and Hct were compared between each group.
Results
Sixty patients were eligible in this study. Median age was 51 years old. There was male predominance (83.33%). Most common indication for transfusion was post-operative anemia (88.33%). There were 20 patients per each group. All baseline characteristics were not significantly different in each group which included age, sex, body weight, body surface area, transfusion indication, creatinine clearance, transfusion volume, congestive heart failure history, diuretics use, fever, intravenous fluid, blood group, baseline Hb and Hct. The median volume of red cell transfusion was 260.00, 262.50 and 257.50 ml for each group (P=0.638), Baseline median Hb before transfusion was 8.60, 8.50 and 8.60 g/dL for each group (P=0.553). Baseline median Hct before transfusion was 26.65, 26.30 and 27.05% for each group (P=0.570). Mean difference of Hb level among different time point at 1, 4 and 24 hours was 1.21, 1.19 and 0.95 g/dL for each group (P=0.109), Mean difference of Hct level among different time point at 1, 4 and 24 hours was 3.62, 3.63 and 3.09% for each group (P=0.398). The equilibration of Hb and Hct after red cell transfusion was not statistically different between these three groups.
Conclusion
The equilibration of Hb and Hct after transfusion was not different at 1, 4 and 24 hours. Target Hb and Hct can be determined at 1 hour after transfusion which can provide early further treatment.
Session topic: E-poster
Keyword(s): Blood transfusion
Type: Publication Only
Background
Target hemoglobin (Hb) varies among different clinical situations but mainly at 7 g/dL. Many institutes include ours follow Hb and hematocrit (Hct) after transfusion at 4 hours for achieving target level. But previous study showed that equilibration after red cell transfusion was at 24 hours. We sought to find out the appropriate time point after red cell transfusion. The result may help physicians to provide earlier and proper treatment.
Aims
This research was aimed to determine the equilibration time point of Hb and Hct after red cell transfusion.
Methods
This is a prospective randomized trial conducted from December 2014 to August 2015 at Chiang Mai University Hospital. Inclusion criteria was adult patient who received 1 unit of red cell without active bleeding and hemolysis. Number of patient was calculated by match pair method from previous study. Hb and Hct were measured at baseline before transfusion. Patients were randomized into 3 groups according to baseline characteristics to follow Hb and Hct at 1, 4 or 24 hours after transfusion. Mean difference of Hb and Hct were compared between each group.
Results
Sixty patients were eligible in this study. Median age was 51 years old. There was male predominance (83.33%). Most common indication for transfusion was post-operative anemia (88.33%). There were 20 patients per each group. All baseline characteristics were not significantly different in each group which included age, sex, body weight, body surface area, transfusion indication, creatinine clearance, transfusion volume, congestive heart failure history, diuretics use, fever, intravenous fluid, blood group, baseline Hb and Hct. The median volume of red cell transfusion was 260.00, 262.50 and 257.50 ml for each group (P=0.638), Baseline median Hb before transfusion was 8.60, 8.50 and 8.60 g/dL for each group (P=0.553). Baseline median Hct before transfusion was 26.65, 26.30 and 27.05% for each group (P=0.570). Mean difference of Hb level among different time point at 1, 4 and 24 hours was 1.21, 1.19 and 0.95 g/dL for each group (P=0.109), Mean difference of Hct level among different time point at 1, 4 and 24 hours was 3.62, 3.63 and 3.09% for each group (P=0.398). The equilibration of Hb and Hct after red cell transfusion was not statistically different between these three groups.
Conclusion
The equilibration of Hb and Hct after transfusion was not different at 1, 4 and 24 hours. Target Hb and Hct can be determined at 1 hour after transfusion which can provide early further treatment.
Session topic: E-poster
Keyword(s): Blood transfusion
Abstract: PB2221
Type: Publication Only
Background
Target hemoglobin (Hb) varies among different clinical situations but mainly at 7 g/dL. Many institutes include ours follow Hb and hematocrit (Hct) after transfusion at 4 hours for achieving target level. But previous study showed that equilibration after red cell transfusion was at 24 hours. We sought to find out the appropriate time point after red cell transfusion. The result may help physicians to provide earlier and proper treatment.
Aims
This research was aimed to determine the equilibration time point of Hb and Hct after red cell transfusion.
Methods
This is a prospective randomized trial conducted from December 2014 to August 2015 at Chiang Mai University Hospital. Inclusion criteria was adult patient who received 1 unit of red cell without active bleeding and hemolysis. Number of patient was calculated by match pair method from previous study. Hb and Hct were measured at baseline before transfusion. Patients were randomized into 3 groups according to baseline characteristics to follow Hb and Hct at 1, 4 or 24 hours after transfusion. Mean difference of Hb and Hct were compared between each group.
Results
Sixty patients were eligible in this study. Median age was 51 years old. There was male predominance (83.33%). Most common indication for transfusion was post-operative anemia (88.33%). There were 20 patients per each group. All baseline characteristics were not significantly different in each group which included age, sex, body weight, body surface area, transfusion indication, creatinine clearance, transfusion volume, congestive heart failure history, diuretics use, fever, intravenous fluid, blood group, baseline Hb and Hct. The median volume of red cell transfusion was 260.00, 262.50 and 257.50 ml for each group (P=0.638), Baseline median Hb before transfusion was 8.60, 8.50 and 8.60 g/dL for each group (P=0.553). Baseline median Hct before transfusion was 26.65, 26.30 and 27.05% for each group (P=0.570). Mean difference of Hb level among different time point at 1, 4 and 24 hours was 1.21, 1.19 and 0.95 g/dL for each group (P=0.109), Mean difference of Hct level among different time point at 1, 4 and 24 hours was 3.62, 3.63 and 3.09% for each group (P=0.398). The equilibration of Hb and Hct after red cell transfusion was not statistically different between these three groups.
Conclusion
The equilibration of Hb and Hct after transfusion was not different at 1, 4 and 24 hours. Target Hb and Hct can be determined at 1 hour after transfusion which can provide early further treatment.
Session topic: E-poster
Keyword(s): Blood transfusion
Type: Publication Only
Background
Target hemoglobin (Hb) varies among different clinical situations but mainly at 7 g/dL. Many institutes include ours follow Hb and hematocrit (Hct) after transfusion at 4 hours for achieving target level. But previous study showed that equilibration after red cell transfusion was at 24 hours. We sought to find out the appropriate time point after red cell transfusion. The result may help physicians to provide earlier and proper treatment.
Aims
This research was aimed to determine the equilibration time point of Hb and Hct after red cell transfusion.
Methods
This is a prospective randomized trial conducted from December 2014 to August 2015 at Chiang Mai University Hospital. Inclusion criteria was adult patient who received 1 unit of red cell without active bleeding and hemolysis. Number of patient was calculated by match pair method from previous study. Hb and Hct were measured at baseline before transfusion. Patients were randomized into 3 groups according to baseline characteristics to follow Hb and Hct at 1, 4 or 24 hours after transfusion. Mean difference of Hb and Hct were compared between each group.
Results
Sixty patients were eligible in this study. Median age was 51 years old. There was male predominance (83.33%). Most common indication for transfusion was post-operative anemia (88.33%). There were 20 patients per each group. All baseline characteristics were not significantly different in each group which included age, sex, body weight, body surface area, transfusion indication, creatinine clearance, transfusion volume, congestive heart failure history, diuretics use, fever, intravenous fluid, blood group, baseline Hb and Hct. The median volume of red cell transfusion was 260.00, 262.50 and 257.50 ml for each group (P=0.638), Baseline median Hb before transfusion was 8.60, 8.50 and 8.60 g/dL for each group (P=0.553). Baseline median Hct before transfusion was 26.65, 26.30 and 27.05% for each group (P=0.570). Mean difference of Hb level among different time point at 1, 4 and 24 hours was 1.21, 1.19 and 0.95 g/dL for each group (P=0.109), Mean difference of Hct level among different time point at 1, 4 and 24 hours was 3.62, 3.63 and 3.09% for each group (P=0.398). The equilibration of Hb and Hct after red cell transfusion was not statistically different between these three groups.
Conclusion
The equilibration of Hb and Hct after transfusion was not different at 1, 4 and 24 hours. Target Hb and Hct can be determined at 1 hour after transfusion which can provide early further treatment.
Session topic: E-poster
Keyword(s): Blood transfusion
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