MANAGEMENT OF CHRONIC IMMUNE THROMBOCYTOPENIA, SINGLE CENTRE EXPERIENCE
(Abstract release date: 05/19/16)
EHA Library. Ionita H. 06/09/16; 134993; PB2093
Prof. Hortensia Ionita
Contributions
Contributions
Abstract
Abstract: PB2093
Type: Publication Only
Background
The investigation and management of patients with Chronic immune thrombocytopenic purpura (ITP) varies widely.
Aims
To evaluate the treatment of ITP patients in Departament of Hematology, County Hospital, Timisoara during 10 years (I.2000 –XII.2014).
Methods
A retrospective study for 325 ITP patients was performed. Patients demographics, medical history, current treatments and side effects, were abstracted from the patient’s medical charts for the 12 months prior to their most recent visit.
Results
The average age was 43.2 years, with 57% women and 43% men. Median time from the diagnosis of ITP to the start of the observational period was 20 months. Prior to the observational period, 34% of patients have been splenectomized and the most used treatment was corticosteroids. During the observational period, 76% of the patients were treated. The most frequent reasons given for treatment was low platelet count (67%), followed by bleeding symptoms (53%). Corticosteroids represented 64% of treatments, followed by IVIg (20%), azathioprine (8%), rituximab (8%) . Only a few patients (six) were treated with Nplate (Romiplostim). Splenectomies (15% of patients) and platelet transfusions (32% of patients) were performed during the observational period. For monitoring the platelet levels, 78% of patients visited their hematologist 1 to 10 times during the observation. Main reasons for a visit were low platelet count (46% of visits) and bleeding (37% of visits). Overall, 39% of patients required hospitalization. Mean duration of hospitalization was10,5 days.
Conclusion
The retrospective study of 325 patients provides therapeutic outcomes resulting from treatment methods from our department. It showed that bleeding symptoms remained quite frequent among patients with chronic ITP, but lifethreatening bleeding rarely occur. Corticosteroids and splenectomy represent the most used treatments from our department.
Session topic: E-poster
Type: Publication Only
Background
The investigation and management of patients with Chronic immune thrombocytopenic purpura (ITP) varies widely.
Aims
To evaluate the treatment of ITP patients in Departament of Hematology, County Hospital, Timisoara during 10 years (I.2000 –XII.2014).
Methods
A retrospective study for 325 ITP patients was performed. Patients demographics, medical history, current treatments and side effects, were abstracted from the patient’s medical charts for the 12 months prior to their most recent visit.
Results
The average age was 43.2 years, with 57% women and 43% men. Median time from the diagnosis of ITP to the start of the observational period was 20 months. Prior to the observational period, 34% of patients have been splenectomized and the most used treatment was corticosteroids. During the observational period, 76% of the patients were treated. The most frequent reasons given for treatment was low platelet count (67%), followed by bleeding symptoms (53%). Corticosteroids represented 64% of treatments, followed by IVIg (20%), azathioprine (8%), rituximab (8%) . Only a few patients (six) were treated with Nplate (Romiplostim). Splenectomies (15% of patients) and platelet transfusions (32% of patients) were performed during the observational period. For monitoring the platelet levels, 78% of patients visited their hematologist 1 to 10 times during the observation. Main reasons for a visit were low platelet count (46% of visits) and bleeding (37% of visits). Overall, 39% of patients required hospitalization. Mean duration of hospitalization was10,5 days.
Conclusion
The retrospective study of 325 patients provides therapeutic outcomes resulting from treatment methods from our department. It showed that bleeding symptoms remained quite frequent among patients with chronic ITP, but lifethreatening bleeding rarely occur. Corticosteroids and splenectomy represent the most used treatments from our department.
Session topic: E-poster
Abstract: PB2093
Type: Publication Only
Background
The investigation and management of patients with Chronic immune thrombocytopenic purpura (ITP) varies widely.
Aims
To evaluate the treatment of ITP patients in Departament of Hematology, County Hospital, Timisoara during 10 years (I.2000 –XII.2014).
Methods
A retrospective study for 325 ITP patients was performed. Patients demographics, medical history, current treatments and side effects, were abstracted from the patient’s medical charts for the 12 months prior to their most recent visit.
Results
The average age was 43.2 years, with 57% women and 43% men. Median time from the diagnosis of ITP to the start of the observational period was 20 months. Prior to the observational period, 34% of patients have been splenectomized and the most used treatment was corticosteroids. During the observational period, 76% of the patients were treated. The most frequent reasons given for treatment was low platelet count (67%), followed by bleeding symptoms (53%). Corticosteroids represented 64% of treatments, followed by IVIg (20%), azathioprine (8%), rituximab (8%) . Only a few patients (six) were treated with Nplate (Romiplostim). Splenectomies (15% of patients) and platelet transfusions (32% of patients) were performed during the observational period. For monitoring the platelet levels, 78% of patients visited their hematologist 1 to 10 times during the observation. Main reasons for a visit were low platelet count (46% of visits) and bleeding (37% of visits). Overall, 39% of patients required hospitalization. Mean duration of hospitalization was10,5 days.
Conclusion
The retrospective study of 325 patients provides therapeutic outcomes resulting from treatment methods from our department. It showed that bleeding symptoms remained quite frequent among patients with chronic ITP, but lifethreatening bleeding rarely occur. Corticosteroids and splenectomy represent the most used treatments from our department.
Session topic: E-poster
Type: Publication Only
Background
The investigation and management of patients with Chronic immune thrombocytopenic purpura (ITP) varies widely.
Aims
To evaluate the treatment of ITP patients in Departament of Hematology, County Hospital, Timisoara during 10 years (I.2000 –XII.2014).
Methods
A retrospective study for 325 ITP patients was performed. Patients demographics, medical history, current treatments and side effects, were abstracted from the patient’s medical charts for the 12 months prior to their most recent visit.
Results
The average age was 43.2 years, with 57% women and 43% men. Median time from the diagnosis of ITP to the start of the observational period was 20 months. Prior to the observational period, 34% of patients have been splenectomized and the most used treatment was corticosteroids. During the observational period, 76% of the patients were treated. The most frequent reasons given for treatment was low platelet count (67%), followed by bleeding symptoms (53%). Corticosteroids represented 64% of treatments, followed by IVIg (20%), azathioprine (8%), rituximab (8%) . Only a few patients (six) were treated with Nplate (Romiplostim). Splenectomies (15% of patients) and platelet transfusions (32% of patients) were performed during the observational period. For monitoring the platelet levels, 78% of patients visited their hematologist 1 to 10 times during the observation. Main reasons for a visit were low platelet count (46% of visits) and bleeding (37% of visits). Overall, 39% of patients required hospitalization. Mean duration of hospitalization was10,5 days.
Conclusion
The retrospective study of 325 patients provides therapeutic outcomes resulting from treatment methods from our department. It showed that bleeding symptoms remained quite frequent among patients with chronic ITP, but lifethreatening bleeding rarely occur. Corticosteroids and splenectomy represent the most used treatments from our department.
Session topic: E-poster
{{ help_message }}
{{filter}}