EPIDEMIOLOGY AND PROGNOSIS OF PATIENTS WITH HEMATOLOGIC MALIGNANCIES ADMITTED TO INTENSIVE CARE
(Abstract release date: 05/19/16)
EHA Library. Haifa R. 06/09/16; 134801; PB1901
Dr. Regaieg Haifa
Contributions
Contributions
Abstract
Abstract: PB1901
Type: Publication Only
Background
The hospitalisation in intensive care unit of a patient with malignant haematology constitutes a difficult problem for haematology and intensive care teams.
Aims
-carry out an assessment of activity of the medical intensive care unit of Farhat HACHED hospital in Sousse.-studying demographic and haematological characteristics of these patients and their specific care in the ICU, mostly in terms of organ failure-study the short-term survival of the population-Finally, this study will attempt to identify prognostic factors for ICU mortality.
Methods
Single retrospective study, in the medical intensive care unit of Farhat Hached hospital Sousse on 20 years (1994-2014).this study included 105 patients with haematological malignancies.
Results
During the study period, 6000 patients were hospitalized in the intensive care unit of which 105 (1.75%) had hematologic malignancies. the median age of the study population was 49 years (15-86 years). the sex ratio was 1.56. the 2 most frequent haematological diseases were non-Hodgkin lymphoma and acute myeloid leukaemia. 33,3% of patients were in the diagnosis stage; 51.4% were in relapse or progression stage and 18.1% were in complete remission. the median scores of APACHE and SAPSII scores were respectively 48 and 32. The reason for admission of patients was acute respiratory failure in nearly half the cases. The cause of acute respiratory failure was pneumonia in 54% and an acute oedema of the lungs in 35% of cases. 45% of patients were intubated and ventilated; the median duration of invasive mechanical ventilation was 2 days.27 patients had received non-invasive ventilation therapy (25.5%) at admission. forty two (40%) patients needed treatment with catecholamine’s. the median length of ICU stay was 4 days and the mortality rate in ICU was therefore 73.3%.Independent predictors factors of mortality in intensive care were severity at admission (score SAPSII) (p = 10-3), the use of invasive mechanical ventilation (p = 0.015), and the use of catecholamine’s (p = 0.038).
Conclusion
The short-term prognosis, according to this study, is exclusively predicted severity at admission, the use of invasive mechanical ventilation, and the use of catecholamines. According to recent data, discussion between haematologist and intensive care, the very early admitted patients and non invasive ventilation seem to improve survival.
Session topic: E-poster
Keyword(s): Salvage therapy
Type: Publication Only
Background
The hospitalisation in intensive care unit of a patient with malignant haematology constitutes a difficult problem for haematology and intensive care teams.
Aims
-carry out an assessment of activity of the medical intensive care unit of Farhat HACHED hospital in Sousse.-studying demographic and haematological characteristics of these patients and their specific care in the ICU, mostly in terms of organ failure-study the short-term survival of the population-Finally, this study will attempt to identify prognostic factors for ICU mortality.
Methods
Single retrospective study, in the medical intensive care unit of Farhat Hached hospital Sousse on 20 years (1994-2014).this study included 105 patients with haematological malignancies.
Results
During the study period, 6000 patients were hospitalized in the intensive care unit of which 105 (1.75%) had hematologic malignancies. the median age of the study population was 49 years (15-86 years). the sex ratio was 1.56. the 2 most frequent haematological diseases were non-Hodgkin lymphoma and acute myeloid leukaemia. 33,3% of patients were in the diagnosis stage; 51.4% were in relapse or progression stage and 18.1% were in complete remission. the median scores of APACHE and SAPSII scores were respectively 48 and 32. The reason for admission of patients was acute respiratory failure in nearly half the cases. The cause of acute respiratory failure was pneumonia in 54% and an acute oedema of the lungs in 35% of cases. 45% of patients were intubated and ventilated; the median duration of invasive mechanical ventilation was 2 days.27 patients had received non-invasive ventilation therapy (25.5%) at admission. forty two (40%) patients needed treatment with catecholamine’s. the median length of ICU stay was 4 days and the mortality rate in ICU was therefore 73.3%.Independent predictors factors of mortality in intensive care were severity at admission (score SAPSII) (p = 10-3), the use of invasive mechanical ventilation (p = 0.015), and the use of catecholamine’s (p = 0.038).
Conclusion
The short-term prognosis, according to this study, is exclusively predicted severity at admission, the use of invasive mechanical ventilation, and the use of catecholamines. According to recent data, discussion between haematologist and intensive care, the very early admitted patients and non invasive ventilation seem to improve survival.
Session topic: E-poster
Keyword(s): Salvage therapy
Abstract: PB1901
Type: Publication Only
Background
The hospitalisation in intensive care unit of a patient with malignant haematology constitutes a difficult problem for haematology and intensive care teams.
Aims
-carry out an assessment of activity of the medical intensive care unit of Farhat HACHED hospital in Sousse.-studying demographic and haematological characteristics of these patients and their specific care in the ICU, mostly in terms of organ failure-study the short-term survival of the population-Finally, this study will attempt to identify prognostic factors for ICU mortality.
Methods
Single retrospective study, in the medical intensive care unit of Farhat Hached hospital Sousse on 20 years (1994-2014).this study included 105 patients with haematological malignancies.
Results
During the study period, 6000 patients were hospitalized in the intensive care unit of which 105 (1.75%) had hematologic malignancies. the median age of the study population was 49 years (15-86 years). the sex ratio was 1.56. the 2 most frequent haematological diseases were non-Hodgkin lymphoma and acute myeloid leukaemia. 33,3% of patients were in the diagnosis stage; 51.4% were in relapse or progression stage and 18.1% were in complete remission. the median scores of APACHE and SAPSII scores were respectively 48 and 32. The reason for admission of patients was acute respiratory failure in nearly half the cases. The cause of acute respiratory failure was pneumonia in 54% and an acute oedema of the lungs in 35% of cases. 45% of patients were intubated and ventilated; the median duration of invasive mechanical ventilation was 2 days.27 patients had received non-invasive ventilation therapy (25.5%) at admission. forty two (40%) patients needed treatment with catecholamine’s. the median length of ICU stay was 4 days and the mortality rate in ICU was therefore 73.3%.Independent predictors factors of mortality in intensive care were severity at admission (score SAPSII) (p = 10-3), the use of invasive mechanical ventilation (p = 0.015), and the use of catecholamine’s (p = 0.038).
Conclusion
The short-term prognosis, according to this study, is exclusively predicted severity at admission, the use of invasive mechanical ventilation, and the use of catecholamines. According to recent data, discussion between haematologist and intensive care, the very early admitted patients and non invasive ventilation seem to improve survival.
Session topic: E-poster
Keyword(s): Salvage therapy
Type: Publication Only
Background
The hospitalisation in intensive care unit of a patient with malignant haematology constitutes a difficult problem for haematology and intensive care teams.
Aims
-carry out an assessment of activity of the medical intensive care unit of Farhat HACHED hospital in Sousse.-studying demographic and haematological characteristics of these patients and their specific care in the ICU, mostly in terms of organ failure-study the short-term survival of the population-Finally, this study will attempt to identify prognostic factors for ICU mortality.
Methods
Single retrospective study, in the medical intensive care unit of Farhat Hached hospital Sousse on 20 years (1994-2014).this study included 105 patients with haematological malignancies.
Results
During the study period, 6000 patients were hospitalized in the intensive care unit of which 105 (1.75%) had hematologic malignancies. the median age of the study population was 49 years (15-86 years). the sex ratio was 1.56. the 2 most frequent haematological diseases were non-Hodgkin lymphoma and acute myeloid leukaemia. 33,3% of patients were in the diagnosis stage; 51.4% were in relapse or progression stage and 18.1% were in complete remission. the median scores of APACHE and SAPSII scores were respectively 48 and 32. The reason for admission of patients was acute respiratory failure in nearly half the cases. The cause of acute respiratory failure was pneumonia in 54% and an acute oedema of the lungs in 35% of cases. 45% of patients were intubated and ventilated; the median duration of invasive mechanical ventilation was 2 days.27 patients had received non-invasive ventilation therapy (25.5%) at admission. forty two (40%) patients needed treatment with catecholamine’s. the median length of ICU stay was 4 days and the mortality rate in ICU was therefore 73.3%.Independent predictors factors of mortality in intensive care were severity at admission (score SAPSII) (p = 10-3), the use of invasive mechanical ventilation (p = 0.015), and the use of catecholamine’s (p = 0.038).
Conclusion
The short-term prognosis, according to this study, is exclusively predicted severity at admission, the use of invasive mechanical ventilation, and the use of catecholamines. According to recent data, discussion between haematologist and intensive care, the very early admitted patients and non invasive ventilation seem to improve survival.
Session topic: E-poster
Keyword(s): Salvage therapy
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