PREVALENCE OF LYMPHOPROLIFERATIVE DISEASES IN PATIENTS WITH AUTOIMMUNE DISORDERS
(Abstract release date: 05/19/16)
EHA Library. Djurasinovic V. 06/09/16; 134646; PB1746
Dr. Vladislava Djurasinovic
Contributions
Contributions
Abstract
Abstract: PB1746
Type: Publication Only
Background
Lymphoproliferative disorders can be found in patients with previously diagnosed autoimmune disorder.
Aims
We have evaluated type of lymphproliferative disease in population of pts with autoimmune disorders and differences between genders.
Methods
Data from national registry for lymphoproliferative diseases were analysed. From 1992-2015. there was 45pts, male 9(20%) and female 36(80%), median age 57(33-76)years.
Results
42(93%) of pts previously had autoimmune disesase with average 7,63(0,7-27) years. There were: systemic lupus erythematosus (SLE) 22/36(61%), reumathoid arthritis (RA) 8/36 (22%) and systemic sclerosis (SS) 6/36(17%) in women and SS 5/9 ( 56%), SLE 2/9(22%), RA 1/9(11%), polimiozitis 1/9(11%) in men.40(89%)pts had non Hodgkin lymphoma (NHL), multiple myeloma (MM) 3(7%) and Hodgkin lymphoma 2(4%). In NHL group 20 were DLBCL, indolent 18- NHL foll. and 2 very agressive.
Conclusion
The most frequent autoimmune disorder was SLE in women and SS in men.NHL DLBCL was the most common lymphorpoliferative disease. Pts with these condiotions had higher stage of disease at the diagnosis and there was no difference in survival between male and female pts.
Session topic: E-poster
Keyword(s): Autoimmune disease, B cell lymphoma
Type: Publication Only
Background
Lymphoproliferative disorders can be found in patients with previously diagnosed autoimmune disorder.
Aims
We have evaluated type of lymphproliferative disease in population of pts with autoimmune disorders and differences between genders.
Methods
Data from national registry for lymphoproliferative diseases were analysed. From 1992-2015. there was 45pts, male 9(20%) and female 36(80%), median age 57(33-76)years.
Results
42(93%) of pts previously had autoimmune disesase with average 7,63(0,7-27) years. There were: systemic lupus erythematosus (SLE) 22/36(61%), reumathoid arthritis (RA) 8/36 (22%) and systemic sclerosis (SS) 6/36(17%) in women and SS 5/9 ( 56%), SLE 2/9(22%), RA 1/9(11%), polimiozitis 1/9(11%) in men.40(89%)pts had non Hodgkin lymphoma (NHL), multiple myeloma (MM) 3(7%) and Hodgkin lymphoma 2(4%). In NHL group 20 were DLBCL, indolent 18- NHL foll. and 2 very agressive.
Conclusion
The most frequent autoimmune disorder was SLE in women and SS in men.NHL DLBCL was the most common lymphorpoliferative disease. Pts with these condiotions had higher stage of disease at the diagnosis and there was no difference in survival between male and female pts.
Session topic: E-poster
Keyword(s): Autoimmune disease, B cell lymphoma
Abstract: PB1746
Type: Publication Only
Background
Lymphoproliferative disorders can be found in patients with previously diagnosed autoimmune disorder.
Aims
We have evaluated type of lymphproliferative disease in population of pts with autoimmune disorders and differences between genders.
Methods
Data from national registry for lymphoproliferative diseases were analysed. From 1992-2015. there was 45pts, male 9(20%) and female 36(80%), median age 57(33-76)years.
Results
42(93%) of pts previously had autoimmune disesase with average 7,63(0,7-27) years. There were: systemic lupus erythematosus (SLE) 22/36(61%), reumathoid arthritis (RA) 8/36 (22%) and systemic sclerosis (SS) 6/36(17%) in women and SS 5/9 ( 56%), SLE 2/9(22%), RA 1/9(11%), polimiozitis 1/9(11%) in men.40(89%)pts had non Hodgkin lymphoma (NHL), multiple myeloma (MM) 3(7%) and Hodgkin lymphoma 2(4%). In NHL group 20 were DLBCL, indolent 18- NHL foll. and 2 very agressive.
Conclusion
The most frequent autoimmune disorder was SLE in women and SS in men.NHL DLBCL was the most common lymphorpoliferative disease. Pts with these condiotions had higher stage of disease at the diagnosis and there was no difference in survival between male and female pts.
Session topic: E-poster
Keyword(s): Autoimmune disease, B cell lymphoma
Type: Publication Only
Background
Lymphoproliferative disorders can be found in patients with previously diagnosed autoimmune disorder.
Aims
We have evaluated type of lymphproliferative disease in population of pts with autoimmune disorders and differences between genders.
Methods
Data from national registry for lymphoproliferative diseases were analysed. From 1992-2015. there was 45pts, male 9(20%) and female 36(80%), median age 57(33-76)years.
Results
42(93%) of pts previously had autoimmune disesase with average 7,63(0,7-27) years. There were: systemic lupus erythematosus (SLE) 22/36(61%), reumathoid arthritis (RA) 8/36 (22%) and systemic sclerosis (SS) 6/36(17%) in women and SS 5/9 ( 56%), SLE 2/9(22%), RA 1/9(11%), polimiozitis 1/9(11%) in men.40(89%)pts had non Hodgkin lymphoma (NHL), multiple myeloma (MM) 3(7%) and Hodgkin lymphoma 2(4%). In NHL group 20 were DLBCL, indolent 18- NHL foll. and 2 very agressive.
Conclusion
The most frequent autoimmune disorder was SLE in women and SS in men.NHL DLBCL was the most common lymphorpoliferative disease. Pts with these condiotions had higher stage of disease at the diagnosis and there was no difference in survival between male and female pts.
Session topic: E-poster
Keyword(s): Autoimmune disease, B cell lymphoma
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