FREQUENCY OF REACTIVE BLOOD DONORS IN A TERTIARY CARE HOSPITAL, KARACHI, PAKISTAN
(Abstract release date: 05/19/16)
EHA Library. Nepal B. 06/09/16; 133133; E1584
Dr. Bipin Nepal
Contributions
Contributions
Abstract
Abstract: E1584
Type: Eposter Presentation
Background
Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) are blood-borne viruses and share transmission routes among at-risk populations, specifically injection drug use and remote blood transfusions before modern donor screening for these pathogens, making co-infection common. Morbidity and mortality from infection with HCV in HIV-infected patients are increasing and have become a major challenge in the management of such patients. In recent years, number of patients infected with HBV or HCV or HIV or co-infected with either of the two viruses, has increased tremendously in Karachi population. IDUs (intravenous drug users), MSM (Men who have Sex with Men) and individuals having unsafe sex are among the people who are identified as groups at higher risk of contracting these infections than others. But these studies does not give an exact picture of prevalence and frequency of these infection in Karachi’s population as focus of most of these studies were individuals already involved in behaviors (intravenous drug use and unsafe sex) regarded as high risk behaviors.
Aims
To find the frequency of different types of reactive healthy blood donors at a tertiary care hospital, Karachi, Pakistan.
Methods
The retrospective observational study carried out on both male and female healthy blood donors. Data from complete blood screening from January 2013 to December 2014 were collected and frequency of various types of reactive blood donors was sorted out to get an actual picture. All the blood products were screened for HBV and HIV Using enzyme linkedimmunosorbent assay (Elisa plate washer version 3 and Elisa plate reader stat fax 3200). HCV screening was performed on Architect 2000 SR Chemiluminescent micro plate immune assay (CMIA). Malarial parasite tested by making thick and thin smear seen under microscope. Syphilis was tested by ICT method.
Results
A total number of 6996 healthy donors were received and about 624 were found to have blood screening positive in various combination. The highest numbers of isolates was HbsAg reactive 214, HCV 213, VDRL 170, HIV 26 and 1 case of malarial parasite. More prevalent in male population. In this study there were seven donors found with HCV –VDRL co infection and five co infected with HCV and HbsAg two donors with HIV and HbsAg infected and two donors were HbsAg and VDRL reactive.
Conclusion
This study supports that HBV, HIV and syphilis prevalence is high and HIV prevalence is low in healthy blood donors.
Session topic: E-poster
Type: Eposter Presentation
Background
Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) are blood-borne viruses and share transmission routes among at-risk populations, specifically injection drug use and remote blood transfusions before modern donor screening for these pathogens, making co-infection common. Morbidity and mortality from infection with HCV in HIV-infected patients are increasing and have become a major challenge in the management of such patients. In recent years, number of patients infected with HBV or HCV or HIV or co-infected with either of the two viruses, has increased tremendously in Karachi population. IDUs (intravenous drug users), MSM (Men who have Sex with Men) and individuals having unsafe sex are among the people who are identified as groups at higher risk of contracting these infections than others. But these studies does not give an exact picture of prevalence and frequency of these infection in Karachi’s population as focus of most of these studies were individuals already involved in behaviors (intravenous drug use and unsafe sex) regarded as high risk behaviors.
Aims
To find the frequency of different types of reactive healthy blood donors at a tertiary care hospital, Karachi, Pakistan.
Methods
The retrospective observational study carried out on both male and female healthy blood donors. Data from complete blood screening from January 2013 to December 2014 were collected and frequency of various types of reactive blood donors was sorted out to get an actual picture. All the blood products were screened for HBV and HIV Using enzyme linkedimmunosorbent assay (Elisa plate washer version 3 and Elisa plate reader stat fax 3200). HCV screening was performed on Architect 2000 SR Chemiluminescent micro plate immune assay (CMIA). Malarial parasite tested by making thick and thin smear seen under microscope. Syphilis was tested by ICT method.
Results
A total number of 6996 healthy donors were received and about 624 were found to have blood screening positive in various combination. The highest numbers of isolates was HbsAg reactive 214, HCV 213, VDRL 170, HIV 26 and 1 case of malarial parasite. More prevalent in male population. In this study there were seven donors found with HCV –VDRL co infection and five co infected with HCV and HbsAg two donors with HIV and HbsAg infected and two donors were HbsAg and VDRL reactive.
Conclusion
This study supports that HBV, HIV and syphilis prevalence is high and HIV prevalence is low in healthy blood donors.
Session topic: E-poster
Abstract: E1584
Type: Eposter Presentation
Background
Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) are blood-borne viruses and share transmission routes among at-risk populations, specifically injection drug use and remote blood transfusions before modern donor screening for these pathogens, making co-infection common. Morbidity and mortality from infection with HCV in HIV-infected patients are increasing and have become a major challenge in the management of such patients. In recent years, number of patients infected with HBV or HCV or HIV or co-infected with either of the two viruses, has increased tremendously in Karachi population. IDUs (intravenous drug users), MSM (Men who have Sex with Men) and individuals having unsafe sex are among the people who are identified as groups at higher risk of contracting these infections than others. But these studies does not give an exact picture of prevalence and frequency of these infection in Karachi’s population as focus of most of these studies were individuals already involved in behaviors (intravenous drug use and unsafe sex) regarded as high risk behaviors.
Aims
To find the frequency of different types of reactive healthy blood donors at a tertiary care hospital, Karachi, Pakistan.
Methods
The retrospective observational study carried out on both male and female healthy blood donors. Data from complete blood screening from January 2013 to December 2014 were collected and frequency of various types of reactive blood donors was sorted out to get an actual picture. All the blood products were screened for HBV and HIV Using enzyme linkedimmunosorbent assay (Elisa plate washer version 3 and Elisa plate reader stat fax 3200). HCV screening was performed on Architect 2000 SR Chemiluminescent micro plate immune assay (CMIA). Malarial parasite tested by making thick and thin smear seen under microscope. Syphilis was tested by ICT method.
Results
A total number of 6996 healthy donors were received and about 624 were found to have blood screening positive in various combination. The highest numbers of isolates was HbsAg reactive 214, HCV 213, VDRL 170, HIV 26 and 1 case of malarial parasite. More prevalent in male population. In this study there were seven donors found with HCV –VDRL co infection and five co infected with HCV and HbsAg two donors with HIV and HbsAg infected and two donors were HbsAg and VDRL reactive.
Conclusion
This study supports that HBV, HIV and syphilis prevalence is high and HIV prevalence is low in healthy blood donors.
Session topic: E-poster
Type: Eposter Presentation
Background
Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) are blood-borne viruses and share transmission routes among at-risk populations, specifically injection drug use and remote blood transfusions before modern donor screening for these pathogens, making co-infection common. Morbidity and mortality from infection with HCV in HIV-infected patients are increasing and have become a major challenge in the management of such patients. In recent years, number of patients infected with HBV or HCV or HIV or co-infected with either of the two viruses, has increased tremendously in Karachi population. IDUs (intravenous drug users), MSM (Men who have Sex with Men) and individuals having unsafe sex are among the people who are identified as groups at higher risk of contracting these infections than others. But these studies does not give an exact picture of prevalence and frequency of these infection in Karachi’s population as focus of most of these studies were individuals already involved in behaviors (intravenous drug use and unsafe sex) regarded as high risk behaviors.
Aims
To find the frequency of different types of reactive healthy blood donors at a tertiary care hospital, Karachi, Pakistan.
Methods
The retrospective observational study carried out on both male and female healthy blood donors. Data from complete blood screening from January 2013 to December 2014 were collected and frequency of various types of reactive blood donors was sorted out to get an actual picture. All the blood products were screened for HBV and HIV Using enzyme linkedimmunosorbent assay (Elisa plate washer version 3 and Elisa plate reader stat fax 3200). HCV screening was performed on Architect 2000 SR Chemiluminescent micro plate immune assay (CMIA). Malarial parasite tested by making thick and thin smear seen under microscope. Syphilis was tested by ICT method.
Results
A total number of 6996 healthy donors were received and about 624 were found to have blood screening positive in various combination. The highest numbers of isolates was HbsAg reactive 214, HCV 213, VDRL 170, HIV 26 and 1 case of malarial parasite. More prevalent in male population. In this study there were seven donors found with HCV –VDRL co infection and five co infected with HCV and HbsAg two donors with HIV and HbsAg infected and two donors were HbsAg and VDRL reactive.
Conclusion
This study supports that HBV, HIV and syphilis prevalence is high and HIV prevalence is low in healthy blood donors.
Session topic: E-poster
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