THE OUTCOME OF PREOPERATIVE TRANSFUSION GUIDELINE ON SICKLE CELL DISEASE PATIENTS AT KING FAHD HOSPITAL-JEDDAH (KSA)
(Abstract release date: 05/19/16)
EHA Library. Felemban S. 06/09/16; 133132; E1583
Disclosure(s): I have no disclosure to any organisation
Dr. Sameera Felemban
Contributions
Contributions
Abstract
Abstract: E1583
Type: Eposter Presentation
Background
We have developed a local hospital preoperative transfusion guidelines for sickle cell disease (SCD) patients to reduce the perioperative and the postoperative complications.
Aims
This study was conducted to evaluate the outcome of practice on SCD patients undergoing surgeries in our institution.
Methods
A retrospective review of 75 SCD patients undergoing surgery at King Fahd Hospital, Jeddah, Saudi Arabia was conducted between April 2005 and May 2010. The medical records were reviewed to define the perioperative risks and the postoperative complications in relation to the type of transfusion modality selected.
Results
The medical record of 75 SCD patients who undergoing surgeries were reviewed. Preoperatively, 25.3 % had complete exchange transfusion (CETX), 17.3 % had partial exchange transfusion (PETX), 26.7 % had simple top up transfusion (STX) and 30.7 % had no transfusion (NTX).
The postoperative complications were 20% vaso-occlusive crises (VOC), 2.7% acute chest syndrome (ACS), and 16% had fever. There was 33.3% patients with prolonged duration of the hospital stay. There was no significant difference in the outcome of postoperative fever, VOC, ACS, and the length of hospital stay between all types of transfusion modalities. However, The correlation was highly significant between the pre-operative haemoglobin (Hb) level and postoperative fever (P = .001) and VOC (P = .002).
Interestingly, SCD patients who received hydroxyurea were observed to have less postoperative complication like fever (P = .015) and vaso-occlusive crises (P = .011), while those who received prophylactic heparin in the postoperative period were found to have a reduced length of hospital stay (P = .005) and vaso-occlusive crises (P = .001).
Conclusion
The guidelines for preoperative transfusion in SCD patients was effective in reducing the postoperative morbidity and mortality. However, this guidelines establish the surgical situations where preoperative transfusion is needed and the optimum regimen for different surgical types.
Session topic: E-poster
Keyword(s): Outcome, Sickle cell disease, Surgery, Transfusion
Type: Eposter Presentation
Background
We have developed a local hospital preoperative transfusion guidelines for sickle cell disease (SCD) patients to reduce the perioperative and the postoperative complications.
Aims
This study was conducted to evaluate the outcome of practice on SCD patients undergoing surgeries in our institution.
Methods
A retrospective review of 75 SCD patients undergoing surgery at King Fahd Hospital, Jeddah, Saudi Arabia was conducted between April 2005 and May 2010. The medical records were reviewed to define the perioperative risks and the postoperative complications in relation to the type of transfusion modality selected.
Results
The medical record of 75 SCD patients who undergoing surgeries were reviewed. Preoperatively, 25.3 % had complete exchange transfusion (CETX), 17.3 % had partial exchange transfusion (PETX), 26.7 % had simple top up transfusion (STX) and 30.7 % had no transfusion (NTX).
The postoperative complications were 20% vaso-occlusive crises (VOC), 2.7% acute chest syndrome (ACS), and 16% had fever. There was 33.3% patients with prolonged duration of the hospital stay. There was no significant difference in the outcome of postoperative fever, VOC, ACS, and the length of hospital stay between all types of transfusion modalities. However, The correlation was highly significant between the pre-operative haemoglobin (Hb) level and postoperative fever (P = .001) and VOC (P = .002).
Interestingly, SCD patients who received hydroxyurea were observed to have less postoperative complication like fever (P = .015) and vaso-occlusive crises (P = .011), while those who received prophylactic heparin in the postoperative period were found to have a reduced length of hospital stay (P = .005) and vaso-occlusive crises (P = .001).
Conclusion
The guidelines for preoperative transfusion in SCD patients was effective in reducing the postoperative morbidity and mortality. However, this guidelines establish the surgical situations where preoperative transfusion is needed and the optimum regimen for different surgical types.
Session topic: E-poster
Keyword(s): Outcome, Sickle cell disease, Surgery, Transfusion
Abstract: E1583
Type: Eposter Presentation
Background
We have developed a local hospital preoperative transfusion guidelines for sickle cell disease (SCD) patients to reduce the perioperative and the postoperative complications.
Aims
This study was conducted to evaluate the outcome of practice on SCD patients undergoing surgeries in our institution.
Methods
A retrospective review of 75 SCD patients undergoing surgery at King Fahd Hospital, Jeddah, Saudi Arabia was conducted between April 2005 and May 2010. The medical records were reviewed to define the perioperative risks and the postoperative complications in relation to the type of transfusion modality selected.
Results
The medical record of 75 SCD patients who undergoing surgeries were reviewed. Preoperatively, 25.3 % had complete exchange transfusion (CETX), 17.3 % had partial exchange transfusion (PETX), 26.7 % had simple top up transfusion (STX) and 30.7 % had no transfusion (NTX).
The postoperative complications were 20% vaso-occlusive crises (VOC), 2.7% acute chest syndrome (ACS), and 16% had fever. There was 33.3% patients with prolonged duration of the hospital stay. There was no significant difference in the outcome of postoperative fever, VOC, ACS, and the length of hospital stay between all types of transfusion modalities. However, The correlation was highly significant between the pre-operative haemoglobin (Hb) level and postoperative fever (P = .001) and VOC (P = .002).
Interestingly, SCD patients who received hydroxyurea were observed to have less postoperative complication like fever (P = .015) and vaso-occlusive crises (P = .011), while those who received prophylactic heparin in the postoperative period were found to have a reduced length of hospital stay (P = .005) and vaso-occlusive crises (P = .001).
Conclusion
The guidelines for preoperative transfusion in SCD patients was effective in reducing the postoperative morbidity and mortality. However, this guidelines establish the surgical situations where preoperative transfusion is needed and the optimum regimen for different surgical types.
Session topic: E-poster
Keyword(s): Outcome, Sickle cell disease, Surgery, Transfusion
Type: Eposter Presentation
Background
We have developed a local hospital preoperative transfusion guidelines for sickle cell disease (SCD) patients to reduce the perioperative and the postoperative complications.
Aims
This study was conducted to evaluate the outcome of practice on SCD patients undergoing surgeries in our institution.
Methods
A retrospective review of 75 SCD patients undergoing surgery at King Fahd Hospital, Jeddah, Saudi Arabia was conducted between April 2005 and May 2010. The medical records were reviewed to define the perioperative risks and the postoperative complications in relation to the type of transfusion modality selected.
Results
The medical record of 75 SCD patients who undergoing surgeries were reviewed. Preoperatively, 25.3 % had complete exchange transfusion (CETX), 17.3 % had partial exchange transfusion (PETX), 26.7 % had simple top up transfusion (STX) and 30.7 % had no transfusion (NTX).
The postoperative complications were 20% vaso-occlusive crises (VOC), 2.7% acute chest syndrome (ACS), and 16% had fever. There was 33.3% patients with prolonged duration of the hospital stay. There was no significant difference in the outcome of postoperative fever, VOC, ACS, and the length of hospital stay between all types of transfusion modalities. However, The correlation was highly significant between the pre-operative haemoglobin (Hb) level and postoperative fever (P = .001) and VOC (P = .002).
Interestingly, SCD patients who received hydroxyurea were observed to have less postoperative complication like fever (P = .015) and vaso-occlusive crises (P = .011), while those who received prophylactic heparin in the postoperative period were found to have a reduced length of hospital stay (P = .005) and vaso-occlusive crises (P = .001).
Conclusion
The guidelines for preoperative transfusion in SCD patients was effective in reducing the postoperative morbidity and mortality. However, this guidelines establish the surgical situations where preoperative transfusion is needed and the optimum regimen for different surgical types.
Session topic: E-poster
Keyword(s): Outcome, Sickle cell disease, Surgery, Transfusion
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