ANALYSIS OF DATA CONCERNING PLATELET TRANSFUSIONS DURING A TWO-MONTH PERIOD IN A TERTIARY CARE HOSPITAL
(Abstract release date: 05/19/16)
EHA Library. Voulgaridou V. 06/09/16; 133129; E1580
Dr. Virginia Voulgaridou
Contributions
Contributions
Abstract
Abstract: E1580
Type: Eposter Presentation
Background
Blood Centers should constantly evaluate their policy, get informed about the impact it has in clinical practice and eventually reinforce or modify some attitudes. Platelet transfusions are a subject of controversy concerning the importance of ABO matching, of providing single donor platelets rather than random donor etc.
Aims
The purpose of our study was to analyze data on all platelet transfusions performed in our Institution, in order to draw information about the age of the patients, the type, the blood group and the age of the platelet units issued. We ultimately wanted to examine to what degree the current practice conformed to the principles of our Blood Center, concerning ABO and Rhesus blood group matching, administration of plateletpheresis units (SDPs) rather than random donor platelets (RDPs), issue of units as fresh as possible, avoiding outdating.
Methods
Having defined as one «transfusion event» the administration of one or more platelet units in a 24-hour period for each patient, we registered all platelet transfusion events in our Tertiary Care Hospital in the two month period May – June 2015. For each patient transfused, we registered the age (in order to separate to two categories: adults and pediatric) as well as the type (SDP or RDP) and the «age» of the units. Differences in the ABO and Rh group between the patients and the platelet units they received, were registered and analyzed.
Results
In the two-month period 258 platelet transfusions were performed, 198 in 38 adults (27 men and 11 women, aged 63±17 years) and 60 transfusions in 10 children (5 boys and 5 girls) aged 6,9±2,4 years. In total, 1482 platelet units were administered, of which 1438 RDPs and 44 SDPs. The adults were given SDPs in 9.09% of the transfusion events (18/198). In the remaining transfusion events 1285 platelet units from random donors were administered, in average 7.5±1.98 units per adult patient. The children were given SDPs in 43.33% of the transfusion events (26/60) and RDPs in the remaining transfusion events, with an average of 4.5±1.4 units per child. All SDPs were of ABO and Rh group identical to the patients’, while 31,7% of RDPs were of different ABO group. The following table shows how fresh the platelet units were. In the same 2-month period, disposal of 137 out of 1619 platelet units produced, was registered: 136 (8.4%) RDPs and 1SDP (0.061%).79/137 RDPs and 1 SDP were destroyed due to expiration, 14/137 due to positive serologic and/or molecular testing, 11/137 due to confidential unit exclusion (CUE) and 32/137 RDPs due to other reasons.
Conclusion
The strategy of the Blood Center to provide platelet units of identical ABO blood group to the patient’s, was accomplished 100% in the case of SDPs, but only in 68.2% of the transfusion events during which RDPs were administered.The already satisfactory percentage of «fresh» units (more than 2/3 of units administered, were less than 3 days old) can probably be further improved.It is advisable to investigate whether it would be helpful to increase the proportion of SDPs for adults, at least to the same extent as for pediatric patients.With better planning and better collaboration with the other Blood Centers, the number of units outdated could be minimized.
Session topic: E-poster
Keyword(s): Platelet transfusion
Type: Eposter Presentation
Background
Blood Centers should constantly evaluate their policy, get informed about the impact it has in clinical practice and eventually reinforce or modify some attitudes. Platelet transfusions are a subject of controversy concerning the importance of ABO matching, of providing single donor platelets rather than random donor etc.
Aims
The purpose of our study was to analyze data on all platelet transfusions performed in our Institution, in order to draw information about the age of the patients, the type, the blood group and the age of the platelet units issued. We ultimately wanted to examine to what degree the current practice conformed to the principles of our Blood Center, concerning ABO and Rhesus blood group matching, administration of plateletpheresis units (SDPs) rather than random donor platelets (RDPs), issue of units as fresh as possible, avoiding outdating.
Methods
Having defined as one «transfusion event» the administration of one or more platelet units in a 24-hour period for each patient, we registered all platelet transfusion events in our Tertiary Care Hospital in the two month period May – June 2015. For each patient transfused, we registered the age (in order to separate to two categories: adults and pediatric) as well as the type (SDP or RDP) and the «age» of the units. Differences in the ABO and Rh group between the patients and the platelet units they received, were registered and analyzed.
Results
In the two-month period 258 platelet transfusions were performed, 198 in 38 adults (27 men and 11 women, aged 63±17 years) and 60 transfusions in 10 children (5 boys and 5 girls) aged 6,9±2,4 years. In total, 1482 platelet units were administered, of which 1438 RDPs and 44 SDPs. The adults were given SDPs in 9.09% of the transfusion events (18/198). In the remaining transfusion events 1285 platelet units from random donors were administered, in average 7.5±1.98 units per adult patient. The children were given SDPs in 43.33% of the transfusion events (26/60) and RDPs in the remaining transfusion events, with an average of 4.5±1.4 units per child. All SDPs were of ABO and Rh group identical to the patients’, while 31,7% of RDPs were of different ABO group. The following table shows how fresh the platelet units were. In the same 2-month period, disposal of 137 out of 1619 platelet units produced, was registered: 136 (8.4%) RDPs and 1SDP (0.061%).79/137 RDPs and 1 SDP were destroyed due to expiration, 14/137 due to positive serologic and/or molecular testing, 11/137 due to confidential unit exclusion (CUE) and 32/137 RDPs due to other reasons.
| Day since the unit was produced | 1st day | 2nd day | 3rd day | 4th day | 5th day |
| Units from random donors (n=1482) | 475 (32.05%) | 446 (30.09%) | 256 (17.27%) | 222 (14.98%) | 83 (5.6%) |
| SDPs (n=44) | 15 (34.09%) | 10 (22.72%) | 6 (13.63%) | 7 (15.9%) | 6 (13.63%) |
Conclusion
The strategy of the Blood Center to provide platelet units of identical ABO blood group to the patient’s, was accomplished 100% in the case of SDPs, but only in 68.2% of the transfusion events during which RDPs were administered.The already satisfactory percentage of «fresh» units (more than 2/3 of units administered, were less than 3 days old) can probably be further improved.It is advisable to investigate whether it would be helpful to increase the proportion of SDPs for adults, at least to the same extent as for pediatric patients.With better planning and better collaboration with the other Blood Centers, the number of units outdated could be minimized.
Session topic: E-poster
Keyword(s): Platelet transfusion
Abstract: E1580
Type: Eposter Presentation
Background
Blood Centers should constantly evaluate their policy, get informed about the impact it has in clinical practice and eventually reinforce or modify some attitudes. Platelet transfusions are a subject of controversy concerning the importance of ABO matching, of providing single donor platelets rather than random donor etc.
Aims
The purpose of our study was to analyze data on all platelet transfusions performed in our Institution, in order to draw information about the age of the patients, the type, the blood group and the age of the platelet units issued. We ultimately wanted to examine to what degree the current practice conformed to the principles of our Blood Center, concerning ABO and Rhesus blood group matching, administration of plateletpheresis units (SDPs) rather than random donor platelets (RDPs), issue of units as fresh as possible, avoiding outdating.
Methods
Having defined as one «transfusion event» the administration of one or more platelet units in a 24-hour period for each patient, we registered all platelet transfusion events in our Tertiary Care Hospital in the two month period May – June 2015. For each patient transfused, we registered the age (in order to separate to two categories: adults and pediatric) as well as the type (SDP or RDP) and the «age» of the units. Differences in the ABO and Rh group between the patients and the platelet units they received, were registered and analyzed.
Results
In the two-month period 258 platelet transfusions were performed, 198 in 38 adults (27 men and 11 women, aged 63±17 years) and 60 transfusions in 10 children (5 boys and 5 girls) aged 6,9±2,4 years. In total, 1482 platelet units were administered, of which 1438 RDPs and 44 SDPs. The adults were given SDPs in 9.09% of the transfusion events (18/198). In the remaining transfusion events 1285 platelet units from random donors were administered, in average 7.5±1.98 units per adult patient. The children were given SDPs in 43.33% of the transfusion events (26/60) and RDPs in the remaining transfusion events, with an average of 4.5±1.4 units per child. All SDPs were of ABO and Rh group identical to the patients’, while 31,7% of RDPs were of different ABO group. The following table shows how fresh the platelet units were. In the same 2-month period, disposal of 137 out of 1619 platelet units produced, was registered: 136 (8.4%) RDPs and 1SDP (0.061%).79/137 RDPs and 1 SDP were destroyed due to expiration, 14/137 due to positive serologic and/or molecular testing, 11/137 due to confidential unit exclusion (CUE) and 32/137 RDPs due to other reasons.
Conclusion
The strategy of the Blood Center to provide platelet units of identical ABO blood group to the patient’s, was accomplished 100% in the case of SDPs, but only in 68.2% of the transfusion events during which RDPs were administered.The already satisfactory percentage of «fresh» units (more than 2/3 of units administered, were less than 3 days old) can probably be further improved.It is advisable to investigate whether it would be helpful to increase the proportion of SDPs for adults, at least to the same extent as for pediatric patients.With better planning and better collaboration with the other Blood Centers, the number of units outdated could be minimized.
Session topic: E-poster
Keyword(s): Platelet transfusion
Type: Eposter Presentation
Background
Blood Centers should constantly evaluate their policy, get informed about the impact it has in clinical practice and eventually reinforce or modify some attitudes. Platelet transfusions are a subject of controversy concerning the importance of ABO matching, of providing single donor platelets rather than random donor etc.
Aims
The purpose of our study was to analyze data on all platelet transfusions performed in our Institution, in order to draw information about the age of the patients, the type, the blood group and the age of the platelet units issued. We ultimately wanted to examine to what degree the current practice conformed to the principles of our Blood Center, concerning ABO and Rhesus blood group matching, administration of plateletpheresis units (SDPs) rather than random donor platelets (RDPs), issue of units as fresh as possible, avoiding outdating.
Methods
Having defined as one «transfusion event» the administration of one or more platelet units in a 24-hour period for each patient, we registered all platelet transfusion events in our Tertiary Care Hospital in the two month period May – June 2015. For each patient transfused, we registered the age (in order to separate to two categories: adults and pediatric) as well as the type (SDP or RDP) and the «age» of the units. Differences in the ABO and Rh group between the patients and the platelet units they received, were registered and analyzed.
Results
In the two-month period 258 platelet transfusions were performed, 198 in 38 adults (27 men and 11 women, aged 63±17 years) and 60 transfusions in 10 children (5 boys and 5 girls) aged 6,9±2,4 years. In total, 1482 platelet units were administered, of which 1438 RDPs and 44 SDPs. The adults were given SDPs in 9.09% of the transfusion events (18/198). In the remaining transfusion events 1285 platelet units from random donors were administered, in average 7.5±1.98 units per adult patient. The children were given SDPs in 43.33% of the transfusion events (26/60) and RDPs in the remaining transfusion events, with an average of 4.5±1.4 units per child. All SDPs were of ABO and Rh group identical to the patients’, while 31,7% of RDPs were of different ABO group. The following table shows how fresh the platelet units were. In the same 2-month period, disposal of 137 out of 1619 platelet units produced, was registered: 136 (8.4%) RDPs and 1SDP (0.061%).79/137 RDPs and 1 SDP were destroyed due to expiration, 14/137 due to positive serologic and/or molecular testing, 11/137 due to confidential unit exclusion (CUE) and 32/137 RDPs due to other reasons.
| Day since the unit was produced | 1st day | 2nd day | 3rd day | 4th day | 5th day |
| Units from random donors (n=1482) | 475 (32.05%) | 446 (30.09%) | 256 (17.27%) | 222 (14.98%) | 83 (5.6%) |
| SDPs (n=44) | 15 (34.09%) | 10 (22.72%) | 6 (13.63%) | 7 (15.9%) | 6 (13.63%) |
Conclusion
The strategy of the Blood Center to provide platelet units of identical ABO blood group to the patient’s, was accomplished 100% in the case of SDPs, but only in 68.2% of the transfusion events during which RDPs were administered.The already satisfactory percentage of «fresh» units (more than 2/3 of units administered, were less than 3 days old) can probably be further improved.It is advisable to investigate whether it would be helpful to increase the proportion of SDPs for adults, at least to the same extent as for pediatric patients.With better planning and better collaboration with the other Blood Centers, the number of units outdated could be minimized.
Session topic: E-poster
Keyword(s): Platelet transfusion
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