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SEXUAL DYSFUNCTION AMONG FEMALE LYMPHOMA PATIENTS IN MALAYSIA
Author(s): ,
Diana Leh Ching Ng
Affiliations:
Medicine,University Malaysia Sarawak,Samarahan,Malaysia
,
Gin Gin Gan
Affiliations:
Medicine,University Malaya,Kuala Lumpur,Malaysia
Leong Yeh Chwan
Affiliations:
Medicine,University Malaya,Kuala Lumpur,Malaysia
(Abstract release date: 05/19/16) EHA Library. Gin Gin G. 06/09/16; 132998; E1449
Prof. Dr. Gan Gin Gin
Prof. Dr. Gan Gin Gin
Contributions
Abstract
Abstract: E1449

Type: Eposter Presentation

Background
Sexual dysfunction is a recognized long-term consequence among cancer patients who had received cytotoxic chemotherapy.  Previous studies on female dysfunction were mainly on patients with breast cancer or gynecological malignancies. This is the first study of sexual dysfunction among lymphoma patients in this region.

Aims
To study the prevalence of sexual dysfunction among lymphoma patients and its association factors.

Methods
This is a cross sectional survey which was conducted among female lymphoma patients who attend haematology clinic at University Malaya Medical Centre, Kuala Lumpur, Malaysia. Patients age 18 years and above were recruited and patients with previous gynecological surgery, other previous malignancy and those who are newly diagnosed were excluded. Demographic data and medical history were obtained from patients and medical notes. Patients were interviewed using the validated Female Sexual Function Index (FSFI), European Organization for Research and Treatment of Cancer (EORTC QLQ C30) and Hospital Anxiety and Depression Scale (HADS). Presence of anxiety and/ or depression symptoms were identified with cut off score of 8/21 for each subset. Data were analyzed using SPSS version 21.0. Total sum of FSFI scores were dichotomized into 2 categories; presence and absence of sexual dysfunction based on cut off value of 26.55. Associations between the demographic / clinical factors, HADS groups, and quality of life scores with sexual dysfunction were tested using Pearson Chi-Square or Fischer Exact Test where applicable. 

Results
A total of 107 women aged 51.71 ± 17.48 years (18-89) participated, of which 72 % (n=77) were not sexually active for more than 4 weeks. The main reasons for non-sexually active were 1) no partner, 63.6% (n=49), followed by 2) problems suffered by partners, 24.7% (n=19) and 3) physical problem suffered by patients, 18.2% (n=14). Among those with partners, 70% (n=21) had sexual dysfunction despite being sexually active. Mean score of FSFI for patients with partner was 16.27 (± 10.28). All of these patients had lack of sexual desire. The sexual dysfunction was not significantly associated with demographic characteristics (age group, ethnicity, religion, education levels) or clinical characteristics (presence of comorbidity, remission status, treatment received, progress of treatment). However it was associated with menopausal state X2(1) = 7.366, p=0.007. Presence of anxiety (22.4%) and depression (8.2%) symptoms was not significantly associated with sexual dysfunction. There was no significant association between sexual dysfunction and quality of life.

Conclusion
The prevalence of sexual dysfunction among lymphoma patients were higher than in general populations and unreported by most of our patients. Further study on association of sexual dysfunction and quality of life is needed. Partners' problem should not be neglected in assessment of female patients with sexual dysfunction.



Session topic: E-poster

Keyword(s): Lymphoma
Abstract: E1449

Type: Eposter Presentation

Background
Sexual dysfunction is a recognized long-term consequence among cancer patients who had received cytotoxic chemotherapy.  Previous studies on female dysfunction were mainly on patients with breast cancer or gynecological malignancies. This is the first study of sexual dysfunction among lymphoma patients in this region.

Aims
To study the prevalence of sexual dysfunction among lymphoma patients and its association factors.

Methods
This is a cross sectional survey which was conducted among female lymphoma patients who attend haematology clinic at University Malaya Medical Centre, Kuala Lumpur, Malaysia. Patients age 18 years and above were recruited and patients with previous gynecological surgery, other previous malignancy and those who are newly diagnosed were excluded. Demographic data and medical history were obtained from patients and medical notes. Patients were interviewed using the validated Female Sexual Function Index (FSFI), European Organization for Research and Treatment of Cancer (EORTC QLQ C30) and Hospital Anxiety and Depression Scale (HADS). Presence of anxiety and/ or depression symptoms were identified with cut off score of 8/21 for each subset. Data were analyzed using SPSS version 21.0. Total sum of FSFI scores were dichotomized into 2 categories; presence and absence of sexual dysfunction based on cut off value of 26.55. Associations between the demographic / clinical factors, HADS groups, and quality of life scores with sexual dysfunction were tested using Pearson Chi-Square or Fischer Exact Test where applicable. 

Results
A total of 107 women aged 51.71 ± 17.48 years (18-89) participated, of which 72 % (n=77) were not sexually active for more than 4 weeks. The main reasons for non-sexually active were 1) no partner, 63.6% (n=49), followed by 2) problems suffered by partners, 24.7% (n=19) and 3) physical problem suffered by patients, 18.2% (n=14). Among those with partners, 70% (n=21) had sexual dysfunction despite being sexually active. Mean score of FSFI for patients with partner was 16.27 (± 10.28). All of these patients had lack of sexual desire. The sexual dysfunction was not significantly associated with demographic characteristics (age group, ethnicity, religion, education levels) or clinical characteristics (presence of comorbidity, remission status, treatment received, progress of treatment). However it was associated with menopausal state X2(1) = 7.366, p=0.007. Presence of anxiety (22.4%) and depression (8.2%) symptoms was not significantly associated with sexual dysfunction. There was no significant association between sexual dysfunction and quality of life.

Conclusion
The prevalence of sexual dysfunction among lymphoma patients were higher than in general populations and unreported by most of our patients. Further study on association of sexual dysfunction and quality of life is needed. Partners' problem should not be neglected in assessment of female patients with sexual dysfunction.



Session topic: E-poster

Keyword(s): Lymphoma

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