WERE THE MEASUREMENTS STANDARDIZED SUFFICIENTLY IN PUBLISHED PAPERS ABOUT MEAN PLATELET VOLUME?
(Abstract release date: 05/19/16)
EHA Library. Beyan C. 06/09/16; 132980; E1431
Prof. Cengiz Beyan
Contributions
Contributions
Abstract
Abstract: E1431
Type: Eposter Presentation
Background
Recently, mean platelet volume (MPV) aroused interest of the researchers and several studies about MPV changes in various pathological conditions were published.
Aims
The aim of this study was to evaluate the data accuracy of MPV measurements in these studies.
Methods
The study was performed using the data of 181 studies contain healthy control subjects within 1181 paper about mean platelet volume indexed by PubMed database since 2012.
Results
81 studies (%44.7) were performed retrospectively. Healthy control groups included 80.52 ± 70.51 subjects (mean ± standard deviation). The distributions of gender in 16 (8.8%) and age in 12 studies (6.6%), and platelet counts in 28 studies (15.5%) were not reported. The gender and age groups were not differing significantly by the means of platelet counts (r= -0.40; p >0.05). EDTA, low (1:9) and high concentrate (1:4) citrate were used as an anticoagulant in 112, 7 and 2 studies, respectively and type of anticoagulant was not noted in 60 studies (33.1%). There was no study to compare the different anticoagulants. The instruments of Beckman Coulter, Sysmex, Abbott Cell-Dyn, Siemens ADVIA, Mindray BC-6800, HORIBA ABX Micros 60 and Diatron Abacus Junior B were used for the measurements of MPV in 53, 46, 32, 9, 2, 2, and 1 studies, respectively and the used technology in automated blood cell counting was not specified in 36 studies (19.9%). The MPV values measured with Sysmex was higher significantly than the MPV values measured with Beckman Coulter, Abbott Cell-Dyn and Siemens ADVIA. The MPV measurements varied up to 17.8% by the instruments. The measurement times between 15 minutes-2 hours was significantly different from the measurement times <15 minutes and >2 hours. The MPV measurement times from venipuncture were not indicated in 86 studies (47.5%). The MPV measurements by the MPV measurement times and plus the used instruments varied up to 17.8% and 27.7%, respectively. Both the MPV measurement times and used instruments were not stated in 29 studies (16.0%). Only 47 prospective studies (26.0%) enlightened about type of anticoagulant, used instruments for MPV measurement, MPV measurement time, platelet counts and MPV values.
Conclusion
As a result, the measurements were not standardized sufficiently in published papers about MPV. It may be explained the differences between the results of studies made same pathological conditions.
Session topic: E-poster
Keyword(s): Platelet, Platelet count
Type: Eposter Presentation
Background
Recently, mean platelet volume (MPV) aroused interest of the researchers and several studies about MPV changes in various pathological conditions were published.
Aims
The aim of this study was to evaluate the data accuracy of MPV measurements in these studies.
Methods
The study was performed using the data of 181 studies contain healthy control subjects within 1181 paper about mean platelet volume indexed by PubMed database since 2012.
Results
81 studies (%44.7) were performed retrospectively. Healthy control groups included 80.52 ± 70.51 subjects (mean ± standard deviation). The distributions of gender in 16 (8.8%) and age in 12 studies (6.6%), and platelet counts in 28 studies (15.5%) were not reported. The gender and age groups were not differing significantly by the means of platelet counts (r= -0.40; p >0.05). EDTA, low (1:9) and high concentrate (1:4) citrate were used as an anticoagulant in 112, 7 and 2 studies, respectively and type of anticoagulant was not noted in 60 studies (33.1%). There was no study to compare the different anticoagulants. The instruments of Beckman Coulter, Sysmex, Abbott Cell-Dyn, Siemens ADVIA, Mindray BC-6800, HORIBA ABX Micros 60 and Diatron Abacus Junior B were used for the measurements of MPV in 53, 46, 32, 9, 2, 2, and 1 studies, respectively and the used technology in automated blood cell counting was not specified in 36 studies (19.9%). The MPV values measured with Sysmex was higher significantly than the MPV values measured with Beckman Coulter, Abbott Cell-Dyn and Siemens ADVIA. The MPV measurements varied up to 17.8% by the instruments. The measurement times between 15 minutes-2 hours was significantly different from the measurement times <15 minutes and >2 hours. The MPV measurement times from venipuncture were not indicated in 86 studies (47.5%). The MPV measurements by the MPV measurement times and plus the used instruments varied up to 17.8% and 27.7%, respectively. Both the MPV measurement times and used instruments were not stated in 29 studies (16.0%). Only 47 prospective studies (26.0%) enlightened about type of anticoagulant, used instruments for MPV measurement, MPV measurement time, platelet counts and MPV values.
Conclusion
As a result, the measurements were not standardized sufficiently in published papers about MPV. It may be explained the differences between the results of studies made same pathological conditions.
Session topic: E-poster
Keyword(s): Platelet, Platelet count
Abstract: E1431
Type: Eposter Presentation
Background
Recently, mean platelet volume (MPV) aroused interest of the researchers and several studies about MPV changes in various pathological conditions were published.
Aims
The aim of this study was to evaluate the data accuracy of MPV measurements in these studies.
Methods
The study was performed using the data of 181 studies contain healthy control subjects within 1181 paper about mean platelet volume indexed by PubMed database since 2012.
Results
81 studies (%44.7) were performed retrospectively. Healthy control groups included 80.52 ± 70.51 subjects (mean ± standard deviation). The distributions of gender in 16 (8.8%) and age in 12 studies (6.6%), and platelet counts in 28 studies (15.5%) were not reported. The gender and age groups were not differing significantly by the means of platelet counts (r= -0.40; p >0.05). EDTA, low (1:9) and high concentrate (1:4) citrate were used as an anticoagulant in 112, 7 and 2 studies, respectively and type of anticoagulant was not noted in 60 studies (33.1%). There was no study to compare the different anticoagulants. The instruments of Beckman Coulter, Sysmex, Abbott Cell-Dyn, Siemens ADVIA, Mindray BC-6800, HORIBA ABX Micros 60 and Diatron Abacus Junior B were used for the measurements of MPV in 53, 46, 32, 9, 2, 2, and 1 studies, respectively and the used technology in automated blood cell counting was not specified in 36 studies (19.9%). The MPV values measured with Sysmex was higher significantly than the MPV values measured with Beckman Coulter, Abbott Cell-Dyn and Siemens ADVIA. The MPV measurements varied up to 17.8% by the instruments. The measurement times between 15 minutes-2 hours was significantly different from the measurement times <15 minutes and >2 hours. The MPV measurement times from venipuncture were not indicated in 86 studies (47.5%). The MPV measurements by the MPV measurement times and plus the used instruments varied up to 17.8% and 27.7%, respectively. Both the MPV measurement times and used instruments were not stated in 29 studies (16.0%). Only 47 prospective studies (26.0%) enlightened about type of anticoagulant, used instruments for MPV measurement, MPV measurement time, platelet counts and MPV values.
Conclusion
As a result, the measurements were not standardized sufficiently in published papers about MPV. It may be explained the differences between the results of studies made same pathological conditions.
Session topic: E-poster
Keyword(s): Platelet, Platelet count
Type: Eposter Presentation
Background
Recently, mean platelet volume (MPV) aroused interest of the researchers and several studies about MPV changes in various pathological conditions were published.
Aims
The aim of this study was to evaluate the data accuracy of MPV measurements in these studies.
Methods
The study was performed using the data of 181 studies contain healthy control subjects within 1181 paper about mean platelet volume indexed by PubMed database since 2012.
Results
81 studies (%44.7) were performed retrospectively. Healthy control groups included 80.52 ± 70.51 subjects (mean ± standard deviation). The distributions of gender in 16 (8.8%) and age in 12 studies (6.6%), and platelet counts in 28 studies (15.5%) were not reported. The gender and age groups were not differing significantly by the means of platelet counts (r= -0.40; p >0.05). EDTA, low (1:9) and high concentrate (1:4) citrate were used as an anticoagulant in 112, 7 and 2 studies, respectively and type of anticoagulant was not noted in 60 studies (33.1%). There was no study to compare the different anticoagulants. The instruments of Beckman Coulter, Sysmex, Abbott Cell-Dyn, Siemens ADVIA, Mindray BC-6800, HORIBA ABX Micros 60 and Diatron Abacus Junior B were used for the measurements of MPV in 53, 46, 32, 9, 2, 2, and 1 studies, respectively and the used technology in automated blood cell counting was not specified in 36 studies (19.9%). The MPV values measured with Sysmex was higher significantly than the MPV values measured with Beckman Coulter, Abbott Cell-Dyn and Siemens ADVIA. The MPV measurements varied up to 17.8% by the instruments. The measurement times between 15 minutes-2 hours was significantly different from the measurement times <15 minutes and >2 hours. The MPV measurement times from venipuncture were not indicated in 86 studies (47.5%). The MPV measurements by the MPV measurement times and plus the used instruments varied up to 17.8% and 27.7%, respectively. Both the MPV measurement times and used instruments were not stated in 29 studies (16.0%). Only 47 prospective studies (26.0%) enlightened about type of anticoagulant, used instruments for MPV measurement, MPV measurement time, platelet counts and MPV values.
Conclusion
As a result, the measurements were not standardized sufficiently in published papers about MPV. It may be explained the differences between the results of studies made same pathological conditions.
Session topic: E-poster
Keyword(s): Platelet, Platelet count
{{ help_message }}
{{filter}}