PREOPERATIVE SCREENING FOR BLEEDING DISORDERS: OUTCOME OF EVALUATION IN CHILDREN WITH ABNORMAL TESTS
(Abstract release date: 05/21/15)
EHA Library. Rajendran A. 06/12/15; 102987; PB1692
Disclosure(s): Sri Ramachandra Medical College and Research InstitutePediatric Hematology Oncology
Aruna Rajendran
Contributions
Contributions
Abstract
Abstract: PB1692
Type: Publication Only
Background
Children prior to invasive procedures undergo screening tests with platelet count and basic ciagulation studies like prothrombin time (PT), Partial Thromboplastin Time (PTT) to identity children with bleeding disorders
Aims
This study aims at studying the outcome of these children with abnormal screening tests or positive bleeding history
Methods
Case records of children who satisfy the inclusion criteria and evaluated in the last 5 years (2009 - 2014) were analyzed for the final diagnosis and surgery details.
Results
Twenty seven children were evaluated during this five years period due to abnormal screening tests or positive bleeding history. Twenty three children tested to have a bleeding disorder with variable severity. Three children did not have any bleeding disorder on evaluation. Two had positive lupus anticoagulant and therefore prolonged PTT. The above five children underwentrequired surgery without excess bleeds. Te diseases picked up during evaluation of children with abnormal screening tests or positive bleeding history were hemophilia (5), von Willebrand disease (type3> type1) (5), mild factor 7 deficiency, mild platelet function disorder(2), Bernard Soulier syndrome (2) and Glanzmann's thrombasthenia. One third of these cjildren underwent surgery with appropriate component replacement.
Summary
These inexpensive screening tests coupled with a good bleeding history is an essential tool to screen children for bleeding risk. This is especially important in children who would have never been challenged till date and this will definitely prevent critical bleeding which might be life threatening
Session topic: Publication Only
Type: Publication Only
Background
Children prior to invasive procedures undergo screening tests with platelet count and basic ciagulation studies like prothrombin time (PT), Partial Thromboplastin Time (PTT) to identity children with bleeding disorders
Aims
This study aims at studying the outcome of these children with abnormal screening tests or positive bleeding history
Methods
Case records of children who satisfy the inclusion criteria and evaluated in the last 5 years (2009 - 2014) were analyzed for the final diagnosis and surgery details.
Results
Twenty seven children were evaluated during this five years period due to abnormal screening tests or positive bleeding history. Twenty three children tested to have a bleeding disorder with variable severity. Three children did not have any bleeding disorder on evaluation. Two had positive lupus anticoagulant and therefore prolonged PTT. The above five children underwentrequired surgery without excess bleeds. Te diseases picked up during evaluation of children with abnormal screening tests or positive bleeding history were hemophilia (5), von Willebrand disease (type3> type1) (5), mild factor 7 deficiency, mild platelet function disorder(2), Bernard Soulier syndrome (2) and Glanzmann's thrombasthenia. One third of these cjildren underwent surgery with appropriate component replacement.
Summary
These inexpensive screening tests coupled with a good bleeding history is an essential tool to screen children for bleeding risk. This is especially important in children who would have never been challenged till date and this will definitely prevent critical bleeding which might be life threatening
Session topic: Publication Only
Abstract: PB1692
Type: Publication Only
Background
Children prior to invasive procedures undergo screening tests with platelet count and basic ciagulation studies like prothrombin time (PT), Partial Thromboplastin Time (PTT) to identity children with bleeding disorders
Aims
This study aims at studying the outcome of these children with abnormal screening tests or positive bleeding history
Methods
Case records of children who satisfy the inclusion criteria and evaluated in the last 5 years (2009 - 2014) were analyzed for the final diagnosis and surgery details.
Results
Twenty seven children were evaluated during this five years period due to abnormal screening tests or positive bleeding history. Twenty three children tested to have a bleeding disorder with variable severity. Three children did not have any bleeding disorder on evaluation. Two had positive lupus anticoagulant and therefore prolonged PTT. The above five children underwentrequired surgery without excess bleeds. Te diseases picked up during evaluation of children with abnormal screening tests or positive bleeding history were hemophilia (5), von Willebrand disease (type3> type1) (5), mild factor 7 deficiency, mild platelet function disorder(2), Bernard Soulier syndrome (2) and Glanzmann's thrombasthenia. One third of these cjildren underwent surgery with appropriate component replacement.
Summary
These inexpensive screening tests coupled with a good bleeding history is an essential tool to screen children for bleeding risk. This is especially important in children who would have never been challenged till date and this will definitely prevent critical bleeding which might be life threatening
Session topic: Publication Only
Type: Publication Only
Background
Children prior to invasive procedures undergo screening tests with platelet count and basic ciagulation studies like prothrombin time (PT), Partial Thromboplastin Time (PTT) to identity children with bleeding disorders
Aims
This study aims at studying the outcome of these children with abnormal screening tests or positive bleeding history
Methods
Case records of children who satisfy the inclusion criteria and evaluated in the last 5 years (2009 - 2014) were analyzed for the final diagnosis and surgery details.
Results
Twenty seven children were evaluated during this five years period due to abnormal screening tests or positive bleeding history. Twenty three children tested to have a bleeding disorder with variable severity. Three children did not have any bleeding disorder on evaluation. Two had positive lupus anticoagulant and therefore prolonged PTT. The above five children underwentrequired surgery without excess bleeds. Te diseases picked up during evaluation of children with abnormal screening tests or positive bleeding history were hemophilia (5), von Willebrand disease (type3> type1) (5), mild factor 7 deficiency, mild platelet function disorder(2), Bernard Soulier syndrome (2) and Glanzmann's thrombasthenia. One third of these cjildren underwent surgery with appropriate component replacement.
Summary
These inexpensive screening tests coupled with a good bleeding history is an essential tool to screen children for bleeding risk. This is especially important in children who would have never been challenged till date and this will definitely prevent critical bleeding which might be life threatening
Session topic: Publication Only
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