ANALYSIS OF THERAPY RESULTS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKAEMIA. A SINGLE CENTER EXPERIENCE IN TURKEY
(Abstract release date: 05/21/15)
EHA Library. Patıroglu T. 06/12/15; 102854; PB1618
Disclosure(s): Erciyes University Medical FacultyPediatric Hematology
Prof. Dr. Turkan Patıroglu
Contributions
Contributions
Abstract
Abstract: PB1618
Type: Publication Only
Background
Prognosis of children with acute lymphoblastic leukemia (ALL) which the most common cancer in childhood, has improved in the last years.
Aims
Methods
The patients diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014 were evaluated retrospectively. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster). Patients were classified into standart-risk (SR), medium-risk (MR) and high-risk (HR) group according to initial leukaemic burden, early treatment response, genotype of leukemia.
Results
A total number of 341 children aged 4 monts -17 years (median age 5.45 years) were diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster).Duration of the chemotherapy was two years. Treatment results were evaluated in 341 children. With a median follow-up of 7 years, event-free-survival (EFS) was 85.4 % and overall survival 86.4 %. Relapse was diagnosed in 14.6 % of the patients.
Summary
Large progress has been made in the treatment of acute lymphoblastic leukaemia of childhood and adolescence over the analyzed period of 14 years. Our results for children with acute lymphoblastic leukaemia are similar to the results in the other BFM study-Group.
Keyword(s): Acute lymphoblastic leukemia, Children, Survival, Treatment
Session topic: Publication Only
Type: Publication Only
Background
Prognosis of children with acute lymphoblastic leukemia (ALL) which the most common cancer in childhood, has improved in the last years.
Aims
Analysis of treatment outcome and identification of prognostic factors in children treated for acute lymphoblastic leukaemia (ALL).
Methods
The patients diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014 were evaluated retrospectively. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster). Patients were classified into standart-risk (SR), medium-risk (MR) and high-risk (HR) group according to initial leukaemic burden, early treatment response, genotype of leukemia.
Results
A total number of 341 children aged 4 monts -17 years (median age 5.45 years) were diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster).Duration of the chemotherapy was two years. Treatment results were evaluated in 341 children. With a median follow-up of 7 years, event-free-survival (EFS) was 85.4 % and overall survival 86.4 %. Relapse was diagnosed in 14.6 % of the patients.
Summary
Large progress has been made in the treatment of acute lymphoblastic leukaemia of childhood and adolescence over the analyzed period of 14 years. Our results for children with acute lymphoblastic leukaemia are similar to the results in the other BFM study-Group.
Keyword(s): Acute lymphoblastic leukemia, Children, Survival, Treatment
Session topic: Publication Only
Abstract: PB1618
Type: Publication Only
Background
Prognosis of children with acute lymphoblastic leukemia (ALL) which the most common cancer in childhood, has improved in the last years.
Aims
Methods
The patients diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014 were evaluated retrospectively. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster). Patients were classified into standart-risk (SR), medium-risk (MR) and high-risk (HR) group according to initial leukaemic burden, early treatment response, genotype of leukemia.
Results
A total number of 341 children aged 4 monts -17 years (median age 5.45 years) were diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster).Duration of the chemotherapy was two years. Treatment results were evaluated in 341 children. With a median follow-up of 7 years, event-free-survival (EFS) was 85.4 % and overall survival 86.4 %. Relapse was diagnosed in 14.6 % of the patients.
Summary
Large progress has been made in the treatment of acute lymphoblastic leukaemia of childhood and adolescence over the analyzed period of 14 years. Our results for children with acute lymphoblastic leukaemia are similar to the results in the other BFM study-Group.
Keyword(s): Acute lymphoblastic leukemia, Children, Survival, Treatment
Session topic: Publication Only
Type: Publication Only
Background
Prognosis of children with acute lymphoblastic leukemia (ALL) which the most common cancer in childhood, has improved in the last years.
Aims
Analysis of treatment outcome and identification of prognostic factors in children treated for acute lymphoblastic leukaemia (ALL).
Methods
The patients diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014 were evaluated retrospectively. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster). Patients were classified into standart-risk (SR), medium-risk (MR) and high-risk (HR) group according to initial leukaemic burden, early treatment response, genotype of leukemia.
Results
A total number of 341 children aged 4 monts -17 years (median age 5.45 years) were diagnosed for ALL in our Hospital of Kayseri-Turkey between 2000-2014. Children were treated according to the protocol of BFM-90 (Berlin-Frankfurt-Münster).Duration of the chemotherapy was two years. Treatment results were evaluated in 341 children. With a median follow-up of 7 years, event-free-survival (EFS) was 85.4 % and overall survival 86.4 %. Relapse was diagnosed in 14.6 % of the patients.
Summary
Large progress has been made in the treatment of acute lymphoblastic leukaemia of childhood and adolescence over the analyzed period of 14 years. Our results for children with acute lymphoblastic leukaemia are similar to the results in the other BFM study-Group.
Keyword(s): Acute lymphoblastic leukemia, Children, Survival, Treatment
Session topic: Publication Only
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