PROGRESSIVE DECLINE OF HBSAG SEROPREVALANCE IN BLOOD DONORS IN NORTHERN TURKEY: THE TWENTY ONE-YEAR EXPERIENCE
(Abstract release date: 05/21/15)
EHA Library. Albayrak D. 06/12/15; 102826; PB2067
Disclosure(s): Samsun Ondokuz Mayis University Faculty Of MedicinePediatric Hematology Department
Davut Albayrak
Contributions
Contributions
Abstract
Abstract: PB2067
Type: Publication Only
Background
The high prevalence of HBV, HCV, HIV-1/2 and treponema pallidum carriers among blood donors has the unpleasant results for cost- effective, transfusion security and contagious disease.
Aims
The aim of this study was to determine the seroprevalence of HBV, HCV, HIV-1/2 and treponema pallidum in blood donors who applied to our Blood Bank in an twenty one –year period retrospectively.
Methods
The single donations and first time donation of repeat donors entered statistical analysis. HBsAg, anti-HCV treponema pallidum and anti-HIV-1/2 screening tests were performed using ELISA kits.
Results
Between 1994 and 2015, total 267,242 blood donation records at the Blood Banks of University were retrieved. Of them 206,027 were first time donors. HBV, HCV, HIV-1/2 and treponema pallidum seroprevalences among these first time donors were analyzed. The mean seroprevalence of HBsAg was 3.6% between 1994 and 2000 years. The rate of HBsAg positivity was unchanged in these seven years. But prevalence began to decrease in 2001. The positivity rates were 3.7% in 2000 and 3.1% in 2001. This difference was significant statistically. This declining continued progressively in later years and the rate dropped to 0.5 % in 2014.
Summary
This retrospective study showed a significant and progressive decline in the HBsAg seropositivity while no apparent change were those of HCV, HIV and T. Pallidum among blood donors in Northern Turkey at last thirteen years. The drop in HBsAg seroprevalence is probably multifactorial such as public education activities and use of mandatory disposable injectors.
Keyword(s): Blood transfusion, Donor, Hepatitis B virus, Transfusion
Session topic: Publication Only
Type: Publication Only
Background
The high prevalence of HBV, HCV, HIV-1/2 and treponema pallidum carriers among blood donors has the unpleasant results for cost- effective, transfusion security and contagious disease.
Aims
The aim of this study was to determine the seroprevalence of HBV, HCV, HIV-1/2 and treponema pallidum in blood donors who applied to our Blood Bank in an twenty one –year period retrospectively.
Methods
The single donations and first time donation of repeat donors entered statistical analysis. HBsAg, anti-HCV treponema pallidum and anti-HIV-1/2 screening tests were performed using ELISA kits.
Results
Between 1994 and 2015, total 267,242 blood donation records at the Blood Banks of University were retrieved. Of them 206,027 were first time donors. HBV, HCV, HIV-1/2 and treponema pallidum seroprevalences among these first time donors were analyzed. The mean seroprevalence of HBsAg was 3.6% between 1994 and 2000 years. The rate of HBsAg positivity was unchanged in these seven years. But prevalence began to decrease in 2001. The positivity rates were 3.7% in 2000 and 3.1% in 2001. This difference was significant statistically. This declining continued progressively in later years and the rate dropped to 0.5 % in 2014.
Summary
This retrospective study showed a significant and progressive decline in the HBsAg seropositivity while no apparent change were those of HCV, HIV and T. Pallidum among blood donors in Northern Turkey at last thirteen years. The drop in HBsAg seroprevalence is probably multifactorial such as public education activities and use of mandatory disposable injectors.
Keyword(s): Blood transfusion, Donor, Hepatitis B virus, Transfusion
Session topic: Publication Only
Abstract: PB2067
Type: Publication Only
Background
The high prevalence of HBV, HCV, HIV-1/2 and treponema pallidum carriers among blood donors has the unpleasant results for cost- effective, transfusion security and contagious disease.
Aims
The aim of this study was to determine the seroprevalence of HBV, HCV, HIV-1/2 and treponema pallidum in blood donors who applied to our Blood Bank in an twenty one –year period retrospectively.
Methods
The single donations and first time donation of repeat donors entered statistical analysis. HBsAg, anti-HCV treponema pallidum and anti-HIV-1/2 screening tests were performed using ELISA kits.
Results
Between 1994 and 2015, total 267,242 blood donation records at the Blood Banks of University were retrieved. Of them 206,027 were first time donors. HBV, HCV, HIV-1/2 and treponema pallidum seroprevalences among these first time donors were analyzed. The mean seroprevalence of HBsAg was 3.6% between 1994 and 2000 years. The rate of HBsAg positivity was unchanged in these seven years. But prevalence began to decrease in 2001. The positivity rates were 3.7% in 2000 and 3.1% in 2001. This difference was significant statistically. This declining continued progressively in later years and the rate dropped to 0.5 % in 2014.
Summary
This retrospective study showed a significant and progressive decline in the HBsAg seropositivity while no apparent change were those of HCV, HIV and T. Pallidum among blood donors in Northern Turkey at last thirteen years. The drop in HBsAg seroprevalence is probably multifactorial such as public education activities and use of mandatory disposable injectors.
Keyword(s): Blood transfusion, Donor, Hepatitis B virus, Transfusion
Session topic: Publication Only
Type: Publication Only
Background
The high prevalence of HBV, HCV, HIV-1/2 and treponema pallidum carriers among blood donors has the unpleasant results for cost- effective, transfusion security and contagious disease.
Aims
The aim of this study was to determine the seroprevalence of HBV, HCV, HIV-1/2 and treponema pallidum in blood donors who applied to our Blood Bank in an twenty one –year period retrospectively.
Methods
The single donations and first time donation of repeat donors entered statistical analysis. HBsAg, anti-HCV treponema pallidum and anti-HIV-1/2 screening tests were performed using ELISA kits.
Results
Between 1994 and 2015, total 267,242 blood donation records at the Blood Banks of University were retrieved. Of them 206,027 were first time donors. HBV, HCV, HIV-1/2 and treponema pallidum seroprevalences among these first time donors were analyzed. The mean seroprevalence of HBsAg was 3.6% between 1994 and 2000 years. The rate of HBsAg positivity was unchanged in these seven years. But prevalence began to decrease in 2001. The positivity rates were 3.7% in 2000 and 3.1% in 2001. This difference was significant statistically. This declining continued progressively in later years and the rate dropped to 0.5 % in 2014.
Summary
This retrospective study showed a significant and progressive decline in the HBsAg seropositivity while no apparent change were those of HCV, HIV and T. Pallidum among blood donors in Northern Turkey at last thirteen years. The drop in HBsAg seroprevalence is probably multifactorial such as public education activities and use of mandatory disposable injectors.
Keyword(s): Blood transfusion, Donor, Hepatitis B virus, Transfusion
Session topic: Publication Only
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