Contributions
Type: Publication Only
Background
The incidence of acute leukemia (AL) in US and European countries is about 5 per 100000 according data from cancer registries. Russian Federal ?ancer Register reported AL incidence rate across the country as about 3 per 100000.
Russian Hematology Society in 2013 initiated the AL population based registry study in which participated 8 regions of Russia Federation. The primary goal was to pre-registry patients for clinical studies, and secondary - to evaluate the epidemiology of AL. 5 regions were included into analysis of epidemiology statistics. The criteria were the fullness and reliability of AL cases registration. Also, only regions with one big hematological center accumulating all AL cases were chosen. All new cases were recorded on-line into special Web based data capture system.
Aims
To evaluate the age-gender specific incidence, profile and other epidemiologic characteristics AL in Russian regions.
Methods
The registry was started at 1st April of 2013 and is ongoing.
Results
169 new ALL cases from Kirov, Ryazan, Kaluga, Tambov regions and Mordovia republic (4,7 M of population) were included into analysis. The distribution by AL subtypes was following: AML - 109 (74,6%), ALL - 31 (21,2%), APL - 5 (3,4%), other - 1 (0,7%). Median age was for AML - 59 (17-85), ALL - 38 (18-80), APL 54 (38-60) years. Gender female/male proportions in AML were – 18/13, in ALL - 54/55, in APL - 4/1. 105 (62,5%) patients are alive; 58(34,5%) - died, 5 (3%) were withdrawn.
The incidence rate estimates by region are listed in table1.
Two regions (Kirov region and Mordovia) with longest duration of registration were taken for age specific incidence calculations. Incidence of AL by age is following: in 15-19 age group – 0.90; in 20-39 age group – 1.13; in 40-59 age group – 2.45; in 60-79 age group – 3.54; in 80-99 age group – 2.18. Total crude incidence in this two regions is 2.09, standardized by WHO population – 1.87.
Summary
The first estimations of AL epidemiology in selected Russian regions was made based on direct registration data from hematological centers. The incidence rate estimations are less than expected. Some explanations may be: incomplete registration of cases, under -diagnostics of AL, non-admission of AL patients to hematological center.
Keyword(s): Acute leukemia
Session topic: Publication Only
Type: Publication Only
Background
The incidence of acute leukemia (AL) in US and European countries is about 5 per 100000 according data from cancer registries. Russian Federal ?ancer Register reported AL incidence rate across the country as about 3 per 100000.
Russian Hematology Society in 2013 initiated the AL population based registry study in which participated 8 regions of Russia Federation. The primary goal was to pre-registry patients for clinical studies, and secondary - to evaluate the epidemiology of AL. 5 regions were included into analysis of epidemiology statistics. The criteria were the fullness and reliability of AL cases registration. Also, only regions with one big hematological center accumulating all AL cases were chosen. All new cases were recorded on-line into special Web based data capture system.
Aims
To evaluate the age-gender specific incidence, profile and other epidemiologic characteristics AL in Russian regions.
Methods
The registry was started at 1st April of 2013 and is ongoing.
Results
169 new ALL cases from Kirov, Ryazan, Kaluga, Tambov regions and Mordovia republic (4,7 M of population) were included into analysis. The distribution by AL subtypes was following: AML - 109 (74,6%), ALL - 31 (21,2%), APL - 5 (3,4%), other - 1 (0,7%). Median age was for AML - 59 (17-85), ALL - 38 (18-80), APL 54 (38-60) years. Gender female/male proportions in AML were – 18/13, in ALL - 54/55, in APL - 4/1. 105 (62,5%) patients are alive; 58(34,5%) - died, 5 (3%) were withdrawn.
The incidence rate estimates by region are listed in table1.
Two regions (Kirov region and Mordovia) with longest duration of registration were taken for age specific incidence calculations. Incidence of AL by age is following: in 15-19 age group – 0.90; in 20-39 age group – 1.13; in 40-59 age group – 2.45; in 60-79 age group – 3.54; in 80-99 age group – 2.18. Total crude incidence in this two regions is 2.09, standardized by WHO population – 1.87.
Summary
The first estimations of AL epidemiology in selected Russian regions was made based on direct registration data from hematological centers. The incidence rate estimations are less than expected. Some explanations may be: incomplete registration of cases, under -diagnostics of AL, non-admission of AL patients to hematological center.
Keyword(s): Acute leukemia
Session topic: Publication Only